WFRF:(Shepherd L)
Sökning: WFRF:(Shepherd L) > (2020-2024) > SARS-CoV-2 entry fa...
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| Fältnamn | Indikatorer | Metadata |
|---|---|---|
| 000 | 06889naa a2202065 4500 | |
| 001 | oai:DiVA.org:kth-273986 | |
| 003 | SwePub | |
| 008 | 200625s2020 | |||||||||||000 ||eng| | |
| 024 | 7 | a https://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-2739862 URI |
| 024 | 7 | a https://doi.org/10.1038/s41591-020-0868-62 DOI |
| 040 | a (SwePub)kth | |
| 041 | a engb eng | |
| 042 | 9 SwePub | |
| 072 | 7 | a ref2 swepub-contenttype |
| 072 | 7 | a art2 swepub-publicationtype |
| 100 | 1 | a Sungnak, W.4 aut |
| 245 | 1 0 | a SARS-CoV-2 entry factors are highly expressed in nasal epithelial cells together with innate immune genes |
| 264 | c 2020-04-23 | |
| 264 | 1 | b Nature Research,c 2020 |
| 338 | a print2 rdacarrier | |
| 500 | a QC 20200625 | |
| 520 | a We investigated SARS-CoV-2 potential tropism by surveying expression of viral entry-associated genes in single-cell RNA-sequencing data from multiple tissues from healthy human donors. We co-detected these transcripts in specific respiratory, corneal and intestinal epithelial cells, potentially explaining the high efficiency of SARS-CoV-2 transmission. These genes are co-expressed in nasal epithelial cells with genes involved in innate immunity, highlighting the cells’ potential role in initial viral infection, spread and clearance. The study offers a useful resource for further lines of inquiry with valuable clinical samples from COVID-19 patients and we provide our data in a comprehensive, open and user-friendly fashion at www.covid19cellatlas.org. | |
| 653 | a angiotensin converting enzyme 2 | |
| 653 | a atp10b protein | |
| 653 | a c15orf48 protein | |
| 653 | a cathepsin B | |
| 653 | a cathepsin L | |
| 653 | a cdc42ep5 protein | |
| 653 | a crym protein | |
| 653 | a cyp2f1 protein | |
| 653 | a duoxa2 protein | |
| 653 | a fam3d protein | |
| 653 | a fcgbp protein | |
| 653 | a ido1 protein | |
| 653 | a lypd2 protein | |
| 653 | a messenger RNA | |
| 653 | a mx1 protein | |
| 653 | a oas1 protein | |
| 653 | a prkar2b protein | |
| 653 | a prostate stem cell antigen | |
| 653 | a protein | |
| 653 | a protein S 100 | |
| 653 | a proteinase | |
| 653 | a rarres1 protein | |
| 653 | a slc5a8 protein | |
| 653 | a spdef protein | |
| 653 | a st3gal4 enzyme | |
| 653 | a st6gal1 enzyme | |
| 653 | a tmprss2 protein | |
| 653 | a ube2l6 protein | |
| 653 | a unclassified drug | |
| 653 | a virus enzyme | |
| 653 | a vitronectin | |
| 653 | a Article | |
| 653 | a colon tissue | |
| 653 | a comparative study | |
| 653 | a cornea epithelium | |
| 653 | a cornea tissue | |
| 653 | a coronavirus disease 2019 | |
| 653 | a epithelium cell | |
| 653 | a esophagus tissue | |
| 653 | a fetus | |
| 653 | a fetus tissue | |
| 653 | a gene expression | |
| 653 | a gene expression level | |
| 653 | a heart tissue | |
| 653 | a human | |
| 653 | a human cell | |
| 653 | a human tissue | |
| 653 | a ileum tissue | |
| 653 | a immune response gene | |
| 653 | a innate immunity | |
| 653 | a kidney tissue | |
| 653 | a liver tissue | |
| 653 | a marker gene | |
| 653 | a muscle tissue | |
| 653 | a nose epithelium | |
| 653 | a pancreas tissue | |
| 653 | a priority journal | |
| 653 | a prostate tissue | |
| 653 | a retina tissue | |
| 653 | a Severe acute respiratory syndrome coronavirus 2 | |
| 653 | a single cell RNA seq | |
| 653 | a skeletal muscle | |
| 653 | a spleen tissue | |
| 653 | a testis tissue | |
| 653 | a viral tropism | |
| 653 | a virus entry | |
| 653 | a virus transmission | |
| 700 | 1 | a Huang, N.4 aut |
| 700 | 1 | a Bécavin, C.4 aut |
| 700 | 1 | a Berg, M.4 aut |
| 700 | 1 | a Queen, R.4 aut |
| 700 | 1 | a Litvinukova, M.4 aut |
| 700 | 1 | a Talavera-López, C.4 aut |
| 700 | 1 | a Maatz, H.4 aut |
| 700 | 1 | a Reichart, D.4 aut |
| 700 | 1 | a Sampaziotis, F.4 aut |
| 700 | 1 | a Worlock, K. B.4 aut |
| 700 | 1 | a Yoshida, M.4 aut |
| 700 | 1 | a Barnes, J. L.4 aut |
| 700 | 1 | a Banovich, N. E.4 aut |
| 700 | 1 | a Barbry, P.4 aut |
| 700 | 1 | a Brazma, A.4 aut |
| 700 | 1 | a Collin, J.4 aut |
| 700 | 1 | a Desai, T. J.4 aut |
| 700 | 1 | a Duong, T. E.4 aut |
| 700 | 1 | a Eickelberg, O.4 aut |
| 700 | 1 | a Falk, C.4 aut |
| 700 | 1 | a Farzan, M.4 aut |
| 700 | 1 | a Glass, I.4 aut |
| 700 | 1 | a Gupta, R. K.4 aut |
| 700 | 1 | a Haniffa, M.4 aut |
| 700 | 1 | a Horvath, P.4 aut |
| 700 | 1 | a Hubner, N.4 aut |
| 700 | 1 | a Hung, D.4 aut |
| 700 | 1 | a Kaminski, N.4 aut |
| 700 | 1 | a Krasnow, M.4 aut |
| 700 | 1 | a Kropski, J. A.4 aut |
| 700 | 1 | a Kuhnemund, M.4 aut |
| 700 | 1 | a Lako, M.4 aut |
| 700 | 1 | a Lee, H.4 aut |
| 700 | 1 | a Leroy, S.4 aut |
| 700 | 1 | a Linnarson, S.4 aut |
| 700 | 1 | a Lundeberg, Joakimu KTH,Science for Life Laboratory, SciLifeLab,Genteknologi4 aut0 (Swepub:kth)u1qkn9kw |
| 700 | 1 | a Meyer, K. B.4 aut |
| 700 | 1 | a Miao, Z.4 aut |
| 700 | 1 | a Misharin, A. V.4 aut |
| 700 | 1 | a Nawijn, M. C.4 aut |
| 700 | 1 | a Nikolic, M. Z.4 aut |
| 700 | 1 | a Noseda, M.4 aut |
| 700 | 1 | a Ordovas-Montanes, J.4 aut |
| 700 | 1 | a Oudit, G. Y.4 aut |
| 700 | 1 | a Pe’er, D.4 aut |
| 700 | 1 | a Powell, J.4 aut |
| 700 | 1 | a Quake, S.4 aut |
| 700 | 1 | a Rajagopal, J.4 aut |
| 700 | 1 | a Tata, P. R.4 aut |
| 700 | 1 | a Rawlins, E. L.4 aut |
| 700 | 1 | a Regev, A.4 aut |
| 700 | 1 | a Reyfman, P. A.4 aut |
| 700 | 1 | a Rozenblatt-Rosen, O.4 aut |
| 700 | 1 | a Saeb-Parsy, K.4 aut |
| 700 | 1 | a Samakovlis, Christosu KTH4 aut0 (Swepub:kth)PI000000 |
| 700 | 1 | a Schiller, H. B.4 aut |
| 700 | 1 | a Schultze, J. L.4 aut |
| 700 | 1 | a Seibold, M. A.4 aut |
| 700 | 1 | a Seidman, C. E.4 aut |
| 700 | 1 | a Seidman, J. G.4 aut |
| 700 | 1 | a Shalek, A. K.4 aut |
| 700 | 1 | a Shepherd, D.4 aut |
| 700 | 1 | a Spence, J.4 aut |
| 700 | 1 | a Spira, A.4 aut |
| 700 | 1 | a Sun, X.4 aut |
| 700 | 1 | a Teichmann, S. A.4 aut |
| 700 | 1 | a Theis, F. J.4 aut |
| 700 | 1 | a Tsankov, A. M.4 aut |
| 700 | 1 | a Vallier, L.4 aut |
| 700 | 1 | a van den Berge, M.4 aut |
| 700 | 1 | a Whitsett, J.4 aut |
| 700 | 1 | a Xavier, R.4 aut |
| 700 | 1 | a Xu, Y.4 aut |
| 700 | 1 | a Zaragosi, L. -E4 aut |
| 700 | 1 | a Zerti, D.4 aut |
| 700 | 1 | a Zhang, H.4 aut |
| 700 | 1 | a Zhang, K.4 aut |
| 700 | 1 | a Rojas, M.4 aut |
| 700 | 1 | a Figueiredo, F.4 aut |
| 700 | 1 | a Network, HCA Lung Biological4 aut |
| 710 | 2 | a KTHb Science for Life Laboratory, SciLifeLab4 org |
| 773 | 0 | t Nature Medicined : Nature Researchg 26:5, s. 681-687q 26:5<681-687x 1078-8956x 1546-170X |
| 856 | 4 | u https://doi.org/10.1038/s41591-020-0868-6y Fulltext |
| 856 | 4 | u https://www.nature.com/articles/s41591-020-0868-6.pdf |
| 856 | 4 8 | u https://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-273986 |
| 856 | 4 8 | u https://doi.org/10.1038/s41591-020-0868-6 |
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- Sungnak, W.
- Huang, N.
- Bécavin, C.
- Berg, M.
- Queen, R.
- Litvinukova, M.
- visa fler...
- Talavera-López, ...
- Maatz, H.
- Reichart, D.
- Sampaziotis, F.
- Worlock, K. B.
- Yoshida, M.
- Barnes, J. L.
- Banovich, N. E.
- Barbry, P.
- Brazma, A.
- Collin, J.
- Desai, T. J.
- Duong, T. E.
- Eickelberg, O.
- Falk, C.
- Farzan, M.
- Glass, I.
- Gupta, R. K.
- Haniffa, M.
- Horvath, P.
- Hubner, N.
- Hung, D.
- Kaminski, N.
- Krasnow, M.
- Kropski, J. A.
- Kuhnemund, M.
- Lako, M.
- Lee, H.
- Leroy, S.
- Linnarson, S.
- Lundeberg, Joaki ...
- Meyer, K. B.
- Miao, Z.
- Misharin, A. V.
- Nawijn, M. C.
- Nikolic, M. Z.
- Noseda, M.
- Ordovas-Montanes ...
- Oudit, G. Y.
- Pe’er, D.
- Powell, J.
- Quake, S.
- Rajagopal, J.
- Tata, P. R.
- Rawlins, E. L.
- Regev, A.
- Reyfman, P. A.
- Rozenblatt-Rosen ...
- Saeb-Parsy, K.
- Samakovlis, Chri ...
- Schiller, H. B.
- Schultze, J. L.
- Seibold, M. A.
- Seidman, C. E.
- Seidman, J. G.
- Shalek, A. K.
- Shepherd, D.
- Spence, J.
- Spira, A.
- Sun, X.
- Teichmann, S. A.
- Theis, F. J.
- Tsankov, A. M.
- Vallier, L.
- van den Berge, M ...
- Whitsett, J.
- Xavier, R.
- Xu, Y.
- Zaragosi, L. -E
- Zerti, D.
- Zhang, H.
- Zhang, K.
- Rojas, M.
- Figueiredo, F.
- Network, HCA Lun ...
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