WFRF:(Skoda Maximilian W.A.)
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| Fältnamn | Indikatorer | Metadata |
|---|---|---|
| 000 | 04533naa a2200493 4500 | |
| 001 | oai:DiVA.org:mau-3971 | |
| 003 | SwePub | |
| 008 | 200228s2015 | |||||||||||000 ||eng| | |
| 009 | oai:lup.lub.lu.se:07f3ee91-0562-47db-b61f-43abd063e27a | |
| 024 | 7 | a https://urn.kb.se/resolve?urn=urn:nbn:se:mau:diva-39712 URI |
| 024 | 7 | a https://doi.org/10.1039/c4sm02296c2 DOI |
| 024 | 7 | a https://lup.lub.lu.se/record/49057842 URI |
| 040 | a (SwePub)maud (SwePub)lu | |
| 041 | a engb eng | |
| 042 | 9 SwePub | |
| 072 | 7 | a ref2 swepub-contenttype |
| 072 | 7 | a art2 swepub-publicationtype |
| 100 | 1 | a Wadsäter, Mariau Lund University,Lunds universitet,Fysikalisk kemi,Enheten för fysikalisk och teoretisk kemi,Kemiska institutionen,Institutioner vid LTH,Lunds Tekniska Högskola,Physical Chemistry,Physical and theoretical chemistry,Department of Chemistry,Departments at LTH,Faculty of Engineering, LTH4 aut0 (Swepub:lu)fkem-mrw |
| 245 | 1 0 | a Structural effects of the dispersing agent polysorbate 80 on liquid crystalline nanoparticles of soy phosphatidylcholine and glycerol dioleate |
| 264 | c 2015 | |
| 264 | 1 | b Royal Society of Chemistry,c 2015 |
| 338 | a print2 rdacarrier | |
| 520 | a Well-defined, stable and highly structured I-2 (Fd (3) over barm) liquid crystalline nanoparticles (LCNP) of 50/50 (wt/wt) soy phosphatidylcholine (SPC)/glycerol dioleate (GDO), can be formed by using a low fraction (5-10 wt%) of the dispersing polymeric surfactant polyoxyethylene (20) sorbitan monooleate (polysorbate 80 or P80). In the present study we used small angle neutron scattering (SANS) and deuterated P80 (d-P80) to determine the location and concentration of P80 within the LCNP and small angle X-ray scattering (SAXS) to reveal the internal structure. SANS data suggests that some d-P80 already penetrates the particle core at 5%. However, the content of d-P80 is still low enough not to significantly change the internal Fd (3) over barm structure of the LCNP. At higher fractions of P80 a phase separation occurs, in which a SPC and P80 rich phase is formed at the particle surface. The surface layer becomes gradually richer in both solvent and d-P80 when the surfactant concentration is increased from 5 to 15%, while the core of the particle is enriched by GDO, resulting in loss of internal structure and reduced hydration. We have used neutron reflectometry to reveal the location of the stabiliser within the adsorbed layer on an anionic silica and cationic (aminopropyltriethoxysilane (APTES) silanized) surface. d-P80 is enriched closest to the supporting surface and slightly more so for the cationic APTES surface. The results are relevant not only for the capability of LCNPs as drug delivery vehicles but also as means of preparing functional surface coatings. | |
| 650 | 7 | a NATURVETENSKAPx Kemix Fysikalisk kemi0 (SwePub)104022 hsv//swe |
| 650 | 7 | a NATURAL SCIENCESx Chemical Sciencesx Physical Chemistry0 (SwePub)104022 hsv//eng |
| 653 | a Chemistry | |
| 653 | a Physical | |
| 653 | a Materials Science | |
| 653 | a Multidisciplinary | |
| 653 | a Physics | |
| 653 | a Multidisciplinary | |
| 653 | a Polymer Science | |
| 700 | 1 | a Barauskas, Justasu Malmö högskola,Institutionen för biomedicinsk vetenskap (BMV)4 aut0 (Swepub:mau)hsjuba |
| 700 | 1 | a Rogers, Sarah4 aut |
| 700 | 1 | a Skoda, Maximilian W. A.4 aut |
| 700 | 1 | a Thomas, Robert K.4 aut |
| 700 | 1 | a Tiberg, Fredriku Lund University,Lunds universitet,Fysikalisk kemi,Enheten för fysikalisk och teoretisk kemi,Kemiska institutionen,Institutioner vid LTH,Lunds Tekniska Högskola,Physical Chemistry,Physical and theoretical chemistry,Department of Chemistry,Departments at LTH,Faculty of Engineering, LTH4 aut0 (Swepub:lu)fk1-fti |
| 700 | 1 | a Nylander, Tommyu Lund University,Lunds universitet,Fysikalisk kemi,Enheten för fysikalisk och teoretisk kemi,Kemiska institutionen,Institutioner vid LTH,Lunds Tekniska Högskola,Physical Chemistry,Physical and theoretical chemistry,Department of Chemistry,Departments at LTH,Faculty of Engineering, LTH4 aut0 (Swepub:lu)fk1-tny |
| 710 | 2 | a Fysikalisk kemib Enheten för fysikalisk och teoretisk kemi4 org |
| 773 | 0 | t Soft Matterd : Royal Society of Chemistryg 11:6, s. 1140-1150q 11:6<1140-1150x 1744-683Xx 1744-6848 |
| 856 | 4 | u http://dx.doi.org/10.1039/c4sm02296cy FULLTEXT |
| 856 | 4 8 | u https://urn.kb.se/resolve?urn=urn:nbn:se:mau:diva-3971 |
| 856 | 4 8 | u https://doi.org/10.1039/c4sm02296c |
| 856 | 4 8 | u https://lup.lub.lu.se/record/4905784 |
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