Sökning: WFRF:(Stark André) >
Comparison of metal...
Comparison of metal ion concentrations and implant survival after total hip arthroplasty with metal-on-metal versus metal-on-polyethylene articulations : a 16-year follow-up of a prospective randomized study
-
- Dahlstrand, Henrik (författare)
- Karolinska Univ Hosp, Karolinska Inst, Sect Orthopaed & Sports Med, Dept Mol Med & Surg, Stockholm, Sweden.
-
- Stark, Andre (författare)
- Karolinska Inst, Danderyd Hosp, Dept Clin Sci, Stockholm, Sweden.
-
- Wick, Marius C. (författare)
- Karolinska Univ Hosp, Karolinska Inst Stockholm, Funct Unit Musculoskeletal Radiol Funct Imaging &, Stockholm, Sweden.
-
visa fler...
-
- Anissian, Lucas (författare)
- Oregon Hlth & Sci Univ, Dept Orthopaed Surg, Portland, OR USA.
-
- Hailer, Nils (författare)
- Uppsala universitet,Ortopedi
-
- Weiss, Rudiger J. (författare)
- Karolinska Univ Hosp, Karolinska Inst, Sect Orthopaed & Sports Med, Dept Mol Med & Surg, Stockholm, Sweden.
-
visa färre...
-
Karolinska Univ Hosp, Karolinska Inst, Sect Orthopaed & Sports Med, Dept Mol Med & Surg, Stockholm, Sweden Karolinska Inst, Danderyd Hosp, Dept Clin Sci, Stockholm, Sweden. (creator_code:org_t)
- 2017-07-12
- 2017
- Engelska.
-
Ingår i: Acta Orthopaedica. - : Medical Journals Sweden AB. - 1745-3674 .- 1745-3682. ; 88:5, s. 490-495
- Relaterad länk:
-
https://www.tandfonl...
-
visa fler...
-
https://urn.kb.se/re...
-
https://doi.org/10.1...
-
visa färre...
Abstract
Ämnesord
Stäng
- Background and purpose - Large metal-on-metal (MoM) articulations are associated with metal wear and corrosion, leading to increased metal ion concentrations and unacceptable revision rates. There are few comparative studies of 28-mm MoM articulations with conventional metal-on-polyethylene (MoP) couplings. We present a long-term follow-up of a randomized controlled trial comparing MoM versus MoP 28-mm articulations, focused on metal ions and implant survival. Patients and methods - 85 patients with a mean age of 65 years at surgery were randomized to a MoM (Metasul) or a MoP (Protasul) bearing. After 16 years, 38 patients had died and 4 had undergone revision surgery. 13 patients were unavailable for clinical follow-up, leaving 30 patients (n = 14 MoM and n = 16 MoP) for analysis of metal ion concentrations and clinical outcome. Results - 15-year implant survival was similar in both groups (MoM 96% [95% CI 88-100] versus MoP 97% [95% CI 91-100]). The mean serum cobalt concentration was 4-fold higher in the MoM (1.5 mu g/L) compared with the MoP cohort (0.4 mu g/L, p < 0.001) and the mean chromium concentration was double in the MoM (2.2 mu g/L) compared with the MoP cohort (1.0 mu g/L, p = 0.05). Mean creatinine levels were similar in both groups (MoM 93 mu mol/L versus MoP 92 mu mol/L). Harris hip scores differed only marginally between the MoM and MoP cohorts. Interpretation - This is the longest follow-up of a randomized trial on 28-mm MoM articulations, and although implant survival in the 2 groups was similar, metal ion concentrations remained elevated in the MoM cohort even in the long term.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Ortopedi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Orthopaedics (hsv//eng)
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
Hitta via bibliotek
Till lärosätets databas