Sökning: WFRF:(Svensson Lola 1948) > The structural basi...
Fältnamn | Indikatorer | Metadata |
---|---|---|
000 | 04161naa a2200421 4500 | |
001 | oai:gup.ub.gu.se/154608 | |
003 | SwePub | |
008 | 240528s2011 | |||||||||||000 ||eng| | |
024 | 7 | a https://gup.ub.gu.se/publication/1546082 URI |
024 | 7 | a https://doi.org/10.1093/glycob/cwq1432 DOI |
040 | a (SwePub)gu | |
041 | a eng | |
042 | 9 SwePub | |
072 | 7 | a ref2 swepub-contenttype |
072 | 7 | a art2 swepub-publicationtype |
100 | 1 | a Svensson, Lola,d 1948u Gothenburg University,Göteborgs universitet,Institutionen för biomedicin, avdelningen för klinisk kemi och transfusionsmedicin,Institute of Biomedicine, Department of Clinical Chemistry and Transfusion Medicine4 aut0 (Swepub:gu)xsvelo |
245 | 1 0 | a The structural basis of blood group A-related glycolipids in an A3 red cell phenotype and potential explanation to a serological phenomenon |
264 | c 2010-10-06 | |
264 | 1 | b Oxford University Press (OUP),c 2011 |
520 | a Glycolipids from the red cells of a rare blood group A subgroup individual, expressing the blood group A(3) phenotype with the classical mixed-field agglutination phenomenon, A(2(539G>A))/O(1) genotype, and an unusual blood group A glycolipid profile, were submitted to a comprehensive biochemical and structural analysis. To determine the nature of blood group A glycolipids in this A(3) phenotype, structural determination was carried out with complementary techniques including proton nuclear magnetic resonance (1D and 2D), mass spectrometry (MS) (nano-electrospray ionization/quadrupole time-of-flight and tandem mass spectrometry) and thin layer chromatography with immunostaining detection. As expected, total blood group A structures were of low abundance, but contrary to expectations extended-A type 2 and A type 3 glycolipids were more dominant than A hexaglycosylceramides based on type 2 chain (A-6-2 glycolipids), which normally is the major A glycolipid. Several para-Forssman (GalNAcbeta3GbO(4)) structures, including extended forms, were identified but surmised not to contribute to the classic mixed-field agglutination of the A(3) phenotype. It is proposed that the low level of A antigen combined with an absence of extended branched glycolipids may be the factor determining the mixed-field agglutination phenomenon in this individual. | |
650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Medicinska och farmaceutiska grundvetenskaperx Andra medicinska och farmaceutiska grundvetenskaper0 (SwePub)301992 hsv//swe |
650 | 7 | a MEDICAL AND HEALTH SCIENCESx Basic Medicinex Other Basic Medicine0 (SwePub)301992 hsv//eng |
653 | a blood group ABO | |
653 | a glycolipid | |
653 | a immunochemistry | |
653 | a mass spectrometry | |
653 | a para-Forssman | |
700 | 1 | a Bindila, Laura4 aut |
700 | 1 | a Ångström, Jonas,d 1950u Gothenburg University,Göteborgs universitet,Institutionen för kliniska vetenskaper,Institute of Clinical Sciences4 aut0 (Swepub:gu)xangjo |
700 | 1 | a Samuelsson, Bo,d 1942u Gothenburg University,Göteborgs universitet,Institutionen för biomedicin, avdelningen för klinisk kemi och transfusionsmedicin,Institute of Biomedicine, Department of Clinical Chemistry and Transfusion Medicine4 aut0 (Swepub:gu)xsamub |
700 | 1 | a Breimer, Michael,d 1951u Gothenburg University,Göteborgs universitet,Institutionen för kliniska vetenskaper,Institute of Clinical Sciences4 aut0 (Swepub:gu)xbremi |
700 | 1 | a Rydberg, Lennart,d 1944u Gothenburg University,Göteborgs universitet,Institutionen för biomedicin, avdelningen för klinisk kemi och transfusionsmedicin,Institute of Biomedicine, Department of Clinical Chemistry and Transfusion Medicine4 aut0 (Swepub:gu)xrydle |
700 | 1 | a Henry, Stephan4 aut |
710 | 2 | a Göteborgs universitetb Institutionen för biomedicin, avdelningen för klinisk kemi och transfusionsmedicin4 org |
773 | 0 | t Glycobiologyd : Oxford University Press (OUP)g 21:2, s. 162-174q 21:2<162-174x 1460-2423x 0959-6658 |
856 | 4 | u https://academic.oup.com/glycob/article-pdf/21/2/162/5844970/cwq143.pdf |
856 | 4 8 | u https://gup.ub.gu.se/publication/154608 |
856 | 4 8 | u https://doi.org/10.1093/glycob/cwq143 |
Kungliga biblioteket hanterar dina personuppgifter i enlighet med EU:s dataskyddsförordning (2018), GDPR. Läs mer om hur det funkar här.
Så här hanterar KB dina uppgifter vid användning av denna tjänst.