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Sökning: WFRF:(Thorvaldsson Valgeir 1976) > Overweight in midli...

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FältnamnIndikatorerMetadata
00004905naa a2200601 4500
001oai:gup.ub.gu.se/96211
003SwePub
008240910s2009 | |||||||||||000 ||eng|
009oai:DiVA.org:hj-9494
009oai:prod.swepub.kib.ki.se:119195387
0247 a https://gup.ub.gu.se/publication/962112 URI
0247 a https://urn.kb.se/resolve?urn=urn:nbn:se:hj:diva-94942 URI
0247 a https://doi.org/10.1038/ijo.2009.1042 DOI
0247 a http://kipublications.ki.se/Default.aspx?queryparsed=id:1191953872 URI
040 a (SwePub)gud (SwePub)hjd (SwePub)ki
041 a eng
042 9 SwePub
072 7a ref2 swepub-contenttype
072 7a art2 swepub-publicationtype
1001 a Hassing, Linda,d 1967u Gothenburg University,Göteborgs universitet,Psykologiska institutionen,Department of Psychology4 aut0 (Swepub:gu)xhasli
2451 0a Overweight in midlife and risk of dementia: a 40-year follow-up study
264 1b Springer,c 2009
520 a Objective: This study examines whether overweight in midlife increases dementia risk later in life. Methods: In 1963 body mass index was assessed in 1152 participants of The Swedish Twin Registry, at the age of 45–65 years. These participants were later screened for dementia in a prospective study with up to 40 years follow-up. A total of 312 participants were diagnosed with dementia. Results: Logistic regression analyses adjusted for demographic factors, smoking and alcohol habits, indicated that men and women categorized as overweight in their midlife had an elevated risk of dementia (OR=1.59; 95% CI: 1.21–2.07, P=0.002), Alzheimer's disease (OR=1.71; 95% CI: 1.24–2.35, P=0.003), and vascular dementia (OR=1.55; 95% CI: 0.98–2.47, P=0.059). Further adjustments for diabetes and vascular diseases did not substantially affect the associations, except for vascular dementia (OR=1.36; 95% CI: 0.82–2.56, P=0.116), reflecting the significance of diabetes and vascular diseases in the etiology of vascular dementia. There was no significant interaction between overweight and APOE alt epsilon4 status, indicating that having both risk factors does not have a multiplicative effect with regard to dementia risk. Conclusions: This study gives further support to the notion that overweight in midlife increases later risk of dementia. The risk is increased for both Alzheimer's disease and vascular dementia, and follows the same pattern for men and women. Keywords: BMI, alzheimer's disease, vascular dementia, dementia, overweight, obesity
650 7a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Psykiatri0 (SwePub)302152 hsv//swe
650 7a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Psychiatry0 (SwePub)302152 hsv//eng
650 7a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Geriatrik0 (SwePub)302222 hsv//swe
650 7a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Geriatrics0 (SwePub)302222 hsv//eng
650 7a SAMHÄLLSVETENSKAPx Annan samhällsvetenskapx Övrig annan samhällsvetenskap0 (SwePub)509992 hsv//swe
650 7a SOCIAL SCIENCESx Other Social Sciencesx Other Social Sciences not elsewhere specified0 (SwePub)509992 hsv//eng
653 a BMI
653 a alzheimer's disease
653 a vascular dementia
653 a dementia
653 a overweight
653 a obesity
653 a body mass index alzheimer's disease vascular dementia dementia overweight obesity
653 a Geriatrics and medical gerontology
653 a Older people and ageing
7001 a Dahl, Anna,d 1975-u Jönköping University,HHJ, Institutet för gerontologi,HHJ. Åldrande - livsvillkor och hälsa4 aut0 (Swepub:hj)daan
7001 a Thorvaldsson, Valgeir,d 1976u Gothenburg University,Göteborgs universitet,Psykologiska institutionen,Department of Psychology4 aut0 (Swepub:gu)xthova
7001 a Berg, Stig,d 1947u Jönköping University,HHJ, Institutet för gerontologi,HHJ. Åldrande - livsvillkor och hälsa4 aut
7001 a Gatz, Maragaret4 aut
7001 a Pedersen, Nancy Lu Karolinska Institutet4 aut
7001 a Johansson, Boou Gothenburg University,Göteborgs universitet,Psykologiska institutionen,Department of Psychology4 aut0 (Swepub:gu)xjoboo
7102 a Göteborgs universitetb Psykologiska institutionen4 org
7730 t International Journal of Obesityd : Springerg 33:8, s. 893-898q 33<893-898
7730 t International Journal of Obesityd : Springerg 33:8, s. 893-898q 33:8<893-898x 0307-0565x 1476-5497
8564 u https://doi.org/10.1038/ijo.2009.104y Fulltext
8564 u https://europepmc.org/articles/pmc3025291?pdf=render
8564 8u https://gup.ub.gu.se/publication/96211
8564 8u https://urn.kb.se/resolve?urn=urn:nbn:se:hj:diva-9494
8564 8u https://doi.org/10.1038/ijo.2009.104
8564 8u http://kipublications.ki.se/Default.aspx?queryparsed=id:119195387

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