Sökning: WFRF:(Bennet C.) > Potential neuroprot...
Fältnamn | Indikatorer | Metadata |
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000 | 03483naa a2200649 4500 | |
001 | oai:gup.ub.gu.se/224369 | |
003 | SwePub | |
008 | 240910s2015 | |||||||||||000 ||eng| | |
024 | 7 | a https://gup.ub.gu.se/publication/2243692 URI |
024 | 7 | a https://doi.org/10.1016/j.ijdevneu.2015.02.0062 DOI |
040 | a (SwePub)gu | |
041 | a eng | |
042 | 9 SwePub | |
072 | 7 | a ref2 swepub-contenttype |
072 | 7 | a art2 swepub-publicationtype |
100 | 1 | a Ranchhod, S. M.4 aut |
245 | 1 0 | a Potential neuroprotective strategies for perinatal infection and inflammation |
264 | c 2015-02-19 | |
264 | 1 | b Wiley,c 2015 |
520 | a Preterm born infants have high rates of brain injury, leading to motor and neurocognitive problems in later life. Infection and resulting inflammation of the fetus and newborn are highly associated with these disabilities. However, there are no established neuroprotective therapies. Microglial activation and expression of many cytokines play a key role in normal brain function and development, as well as being deleterious. Thus, treatment must achieve a delicate balance between possible beneficial and harmful effects. In this review, we discuss potential neuroprotective strategies targeting systemic infection or the resulting systemic and central inflammatory responses. We highlight the central importance of timing of treatment and the critical lack of studies of delayed treatment of infection/inflammation. (C) 2015 Elsevier Ltd. All rights reserved. | |
650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Neurologi0 (SwePub)302072 hsv//swe |
650 | 7 | a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Neurology0 (SwePub)302072 hsv//eng |
650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Medicinska och farmaceutiska grundvetenskaperx Neurovetenskaper0 (SwePub)301052 hsv//swe |
650 | 7 | a MEDICAL AND HEALTH SCIENCESx Basic Medicinex Neurosciences0 (SwePub)301052 hsv//eng |
653 | a Perinatal | |
653 | a Infection | |
653 | a Inflammation | |
653 | a Cytokines | |
653 | a Brain injury | |
653 | a White matter | |
653 | a Lipopolysaccharide | |
653 | a white-matter injury | |
653 | a low-birth-weight | |
653 | a extremely preterm infants | |
653 | a neonatal-rat brain | |
653 | a oligodendrocyte lineage progression | |
653 | a hypoxic-ischemic encephalopathy | |
653 | a necrosis-factor-alpha | |
653 | a periventricular | |
653 | a leukomalacia | |
653 | a systemic inflammation | |
653 | a cerebral-palsy | |
653 | a Developmental Biology | |
653 | a Neurosciences & Neurology | |
700 | 1 | a Gunn, K. C.4 aut |
700 | 1 | a Fowke, T. M.4 aut |
700 | 1 | a Davidson, J. O.4 aut |
700 | 1 | a Lear, C. A.4 aut |
700 | 1 | a Bai, J.4 aut |
700 | 1 | a Bennet, L.4 aut |
700 | 1 | a Mallard, Carina,d 1963u Gothenburg University,Göteborgs universitet,Institutionen för neurovetenskap och fysiologi, sektionen för fysiologi,Institute of Neuroscience and Physiology, Department of Physiology4 aut0 (Swepub:gu)xmallc |
700 | 1 | a Gunn, A. J.4 aut |
700 | 1 | a Dean, J. M.4 aut |
710 | 2 | a Göteborgs universitetb Institutionen för neurovetenskap och fysiologi, sektionen för fysiologi4 org |
773 | 0 | t International Journal of Developmental Neuroscienced : Wileyg 45, s. 44-54q 45<44-54x 0736-5748x 1873-474X |
856 | 4 8 | u https://gup.ub.gu.se/publication/224369 |
856 | 4 8 | u https://doi.org/10.1016/j.ijdevneu.2015.02.006 |
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