WFRF:(Guy Lionel PhD Docent 1980 )
Sökning: WFRF:(Guy Lionel PhD Docent 1980 ) > Genomes of two arch...
- 16 av 26
- Föregående post
- Nästa post
- Till träfflistan
| Fältnamn | Indikatorer | Metadata |
|---|---|---|
| 000 | 03728naa a2200361 4500 | |
| 001 | oai:DiVA.org:uu-364073 | |
| 003 | SwePub | |
| 008 | 181023s2018 | |||||||||||000 ||eng| | |
| 024 | 7 | a https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-3640732 URI |
| 024 | 7 | a https://doi.org/10.1038/s41396-018-0207-92 DOI |
| 040 | a (SwePub)uu | |
| 041 | a engb eng | |
| 042 | 9 SwePub | |
| 072 | 7 | a ref2 swepub-contenttype |
| 072 | 7 | a art2 swepub-publicationtype |
| 100 | 1 | a Lind, Anders E.u Uppsala universitet,Molekylär evolution,Science for Life Laboratory, SciLifeLab4 aut0 (Swepub:uu)andli580 |
| 245 | 1 0 | a Genomes of two archaeal endosymbionts show convergent adaptations to an intracellular lifestyle. |
| 264 | c 2018-07-10 | |
| 264 | 1 | b Springer Science and Business Media LLC,c 2018 |
| 338 | a print2 rdacarrier | |
| 520 | a Endosymbiosis is a widespread phenomenon in the microbial world and can be based on diverse interactions between endosymbiont and host cell. The vast majority of the known endosymbiotic interactions involve bacteria that have invaded eukaryotic host cells. However, methanogenic archaea have been found to thrive in anaerobic, hydrogenosome-containing protists and it was suggested that this symbiosis is based on the transfer of hydrogen. Here, we used culture-independent genomics approaches to sequence the genomes of two distantly related methanogenic endosymbionts that have been acquired in two independent events by closely related anaerobic ciliate hosts Nyctotherus ovalis and Metopus contortus, respectively. The sequences obtained were then validated as originating from the ciliate endosymbionts by in situ probing experiments. Comparative analyses of these genomes and their closest free-living counterparts reveal that the genomes of both endosymbionts are in an early stage of adaptation towards endosymbiosis as evidenced by the large number of genes undergoing pseudogenization. For instance, the observed loss of genes involved in amino acid biosynthesis in both endosymbiont genomes indicates that the endosymbionts rely on their hosts for obtaining several essential nutrients. Furthermore, the endosymbionts appear to have gained significant amounts of genes of potentially secreted proteins, providing targets for future studies aiming to elucidate possible mechanisms underpinning host-interactions. Altogether, our results provide the first genomic insights into prokaryotic endosymbioses from the archaeal domain of life. | |
| 650 | 7 | a NATURVETENSKAPx Biologix Evolutionsbiologi0 (SwePub)106152 hsv//swe |
| 650 | 7 | a NATURAL SCIENCESx Biological Sciencesx Evolutionary Biology0 (SwePub)106152 hsv//eng |
| 700 | 1 | a Lewis, William Hu Uppsala universitet,Molekylär evolution,Science for Life Laboratory, SciLifeLab4 aut0 (Swepub:uu)wille450 |
| 700 | 1 | a Spang, Anjau Uppsala universitet,Molekylär evolution,Science for Life Laboratory, SciLifeLab4 aut0 (Swepub:uu)anjsp250 |
| 700 | 1 | a Guy, Lionel,c PhD, Docent,d 1980-u Uppsala universitet,Molekylär evolution,Science for Life Laboratory, SciLifeLab,Institutionen för medicinsk biokemi och mikrobiologi4 aut0 (Swepub:uu)liogu139 |
| 700 | 1 | a Embley, T Martin4 aut |
| 700 | 1 | a Ettema, Thijs J. G.u Uppsala universitet,Molekylär evolution,Science for Life Laboratory, SciLifeLab4 aut0 (Swepub:uu)thiet468 |
| 710 | 2 | a Uppsala universitetb Molekylär evolution4 org |
| 773 | 0 | t The ISME Journald : Springer Science and Business Media LLCg 12:11, s. 2655-2667q 12:11<2655-2667x 1751-7362x 1751-7370 |
| 856 | 4 | u https://www.nature.com/articles/s41396-018-0207-9.pdf |
| 856 | 4 8 | u https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-364073 |
| 856 | 4 8 | u https://doi.org/10.1038/s41396-018-0207-9 |
- 16 av 26
- Föregående post
- Nästa post
- Till träfflistan
Hitta mer i SwePub
- Av författaren/redakt...
- Lind, Anders E.
- Lewis, William H
- Spang, Anja
- Guy, Lionel, PhD ...
- Embley, T Martin
- Ettema, Thijs J. ...
- Om ämnet
-
- NATURVETENSKAP
- NATURVETENSKAP
- och Biologi
- och Evolutionsbiolog ...
- Artiklar i publikationen
- The ISME Journal
- Av lärosätet
- Uppsala universitet
Sök utanför SwePub
- Sök vidare i:
- Google Book Search
- Google Scholar
Kungliga biblioteket hanterar dina personuppgifter i enlighet med EU:s dataskyddsförordning (2018), GDPR. Läs mer om hur det funkar här.
Så här hanterar KB dina uppgifter vid användning av denna tjänst.
- Copyright © LIBRIS - Nationella bibliotekssystem
- LIBRIS.kb.se
