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Genomic surveillance of omicron B.1.1.529 SARS‐CoV‐2 and its variants between December 2021 and March 2023 in Tamil Nadu, India—A state‐wide prospective longitudinal study

Selvavinayagam, Sivaprakasam T. (författare)
State Public Health Laboratory, Directorate of Public Health and Preventive Medicine DMS Campus, Teynampet Chennai Tamil Nadu India
Suvaithenamudhan, Suvaiyarasan (författare)
Infection and Inflammation, Department of Biotechnology Central University of Tamil Nadu Thiruvarur Tamil Nadu India;School of Biomedical Sciences, Sri Balaji Vidyapeeth (Deemed to be University) Pondicherry India
Yong, Yean K. (författare)
Laboratory Centre Xiamen University Malaysia Sepang Selangor Malaysia;Kelip‐kelip! Center of Excellence for Light Enabling Technologies Xiamen University Malaysia Sepang Selangor Malaysia
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Hemashree, Kannan (författare)
State Public Health Laboratory, Directorate of Public Health and Preventive Medicine DMS Campus, Teynampet Chennai Tamil Nadu India
Rajeshkumar, Manivannan (författare)
State Public Health Laboratory, Directorate of Public Health and Preventive Medicine DMS Campus, Teynampet Chennai Tamil Nadu India
Kumaresan, Anandhazhvar (författare)
State Public Health Laboratory, Directorate of Public Health and Preventive Medicine DMS Campus, Teynampet Chennai Tamil Nadu India
Arthydevi, Parthiban (författare)
State Public Health Laboratory, Directorate of Public Health and Preventive Medicine DMS Campus, Teynampet Chennai Tamil Nadu India
Kannan, Meganathan (författare)
Blood and Vascular Biology, Department of Biotechnology Central University of Tamil Nadu Thiruvarur Tamil Nadu India
Gopalan, Natarajan (författare)
Department of Epidemiology and Public Health Central University of Tamil Nadu Thiruvarur Tamil Nadu India
Vignesh, Ramachandran (författare)
Preclinical Department, Faculty of Medicine, Royal College of Medicine Perak Universiti Kuala Lumpur Ipoh Perak Malaysia
Murugesan, Amudhan (författare)
Department of Microbiology The Government Theni Medical College and Hospital Theni Tamil Nadu India
Sivasankaran, Munusamy P. (författare)
Seattle Children's Research Institute Seattle Washington USA
Sankar, Sathish (författare)
Department of Microbiology, Saveetha Dental College and Hospitals Saveetha Institute of Medical and Technical Science Chennai Tamil Nadu India
Cheedarla, Narayanaiah (författare)
Division of Microbiology and Immunology, Department of Pathology and Laboratory Medicine, Emory University School of Medicine, Emory National Primate Research Center Emory Vaccine Center Atlanta Georgia USA
Anshad, Abdul R. (författare)
Infection and Inflammation, Department of Biotechnology Central University of Tamil Nadu Thiruvarur Tamil Nadu India
Govindaraj, Sakthivel (författare)
Division of Microbiology and Immunology, Department of Pathology and Laboratory Medicine, Emory University School of Medicine, Emory National Primate Research Center Emory Vaccine Center Atlanta Georgia USA
Zhang, Ying (författare)
Kelip‐kelip! Center of Excellence for Light Enabling Technologies Xiamen University Malaysia Sepang Selangor Malaysia;Chemical Engineering Xiamen University Malaysia Sepang Malaysia
Tan, Hong Y. (författare)
Laboratory Centre Xiamen University Malaysia Sepang Selangor Malaysia;School of Traditional Chinese Medicine Xiamen University Malaysia Sepang Malaysia
Larsson, Marie, 1966- (författare)
Linköpings universitet,Avdelningen för molekylär medicin och virologi,Medicinska fakulteten
Saravanan, Shanmugam (författare)
Center for Infectious Diseases, Saveetha Medical College and Hospital, Saveetha Institute of Medical and Technical Sciences (SIMATS) Saveetha University Chennai Tamil Nadu India
Balakrishnan, Pachamuthu (författare)
Center for Infectious Diseases, Saveetha Medical College and Hospital, Saveetha Institute of Medical and Technical Sciences (SIMATS) Saveetha University Chennai Tamil Nadu India
Kulanthaivel, Langeswaran (författare)
Department of Biomedical Science, Science Campus Alagappa University Karaikudi Tamil Nadu India
Singh, Kamalendra (författare)
Bond Life Sciences Center, Department of Veterinary Pathobiology University of Missouri Columbia Missouri USA
Joseph, Narcisse (författare)
Department of Medical Microbiology Universiti Putra Malaysia Kuala Lumpur Malaysia
Velu, Vijayakumar (författare)
Division of Microbiology and Immunology, Department of Pathology and Laboratory Medicine, Emory University School of Medicine, Emory National Primate Research Center Emory Vaccine Center Atlanta Georgia USA
Byrareddy, Siddappa N. (författare)
Department of Pharmacology and Experimental Neuroscience University of Nebraska Medical Center Omaha Nebraska USA
Shankar, Esaki M. (författare)
Infection and Inflammation, Department of Biotechnology Central University of Tamil Nadu Thiruvarur Tamil Nadu India
Raju, Sivadoss (författare)
State Public Health Laboratory, Directorate of Public Health and Preventive Medicine DMS Campus, Teynampet Chennai Tamil Nadu India
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 (creator_code:org_t)
John Wiley & Sons, 2024
2024
Engelska.
Ingår i: Journal of Medical Virology. - : John Wiley & Sons. - 0146-6615 .- 1096-9071. ; 96:2
  • Tidskriftsartikel (refereegranskat)
Abstract Ämnesord
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  • A state-wide prospective longitudinal investigation of the genomic surveillance of the omicron B.1.1.529 SARS-CoV-2 variant and its sublineages in Tamil Nadu, India, was conducted between December 2021 and March 2023. The study aimed to elucidate their mutational patterns and their genetic interrelationship in the Indian population. The study identified several unique mutations at different time-points, which likely could attribute to the changing disease characteristics, transmission, and pathogenicity attributes of omicron variants. The study found that the omicron variant is highly competent in its mutating potentials, and that it continues to evolve in the general population, likely escaping from natural as well as vaccine-induced immune responses. Our findings suggest that continuous surveillance of viral variants at the global scenario is warranted to undertake intervention measures against potentially precarious SARS-CoV-2 variants and their evolution.

Ämnesord

NATURVETENSKAP  -- Biologi -- Mikrobiologi (hsv//swe)
NATURAL SCIENCES  -- Biological Sciences -- Microbiology (hsv//eng)

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