World Workshop on Oral Medicine VI: a systematic review of medication-induced salivary gland dysfunction: prevalence, diagnosis, and treatment

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Fältnamn	Indikatorer	Metadata
000		04322naa a2200637 4500
001		oai:gup.ub.gu.se/223145
003		SwePub
008		240528s2015 \| \|\|\|\|\|\|\|\|\|\|\|000 \|\|eng\|
024	7	a https://gup.ub.gu.se/publication/2231452 URI
024	7	a https://doi.org/10.1007/s00784-015-1488-22 DOI
040		a (SwePub)gu
041		a eng
042		9 SwePub
072	7	a ref2 swepub-contenttype
072	7	a art2 swepub-publicationtype
100	1	a Villa, A.4 aut
245	1 0	a World Workshop on Oral Medicine VI: a systematic review of medication-induced salivary gland dysfunction: prevalence, diagnosis, and treatment
264		c 2015-05-22
264	1	b Springer Science and Business Media LLC,c 2015
520		a Objectives Medication-induced salivary gland dysfunction (MISGD) causes significant morbidity resulting in decreased quality of life. This systematic review assessed the literature on the prevalence, diagnosis, treatment, and prevention of MISGD. Materials and methods Electronic databases were searched for articles related to MISGD through June 2013. Four independent reviewers extracted information regarding study design, study population, interventions, outcomes, and conclusions for each article. Only papers with acceptable degree of relevance, quality of methodology, and strength of evidence were retained for further analysis. Results There were limited data on the epidemiology of MISGD. Furthermore, various methods were used to assess salivary flow rate or xerostomia. Preventive and therapeutic strategies included substitution of medications, oral, or systemic therapy with sialogogues, use of saliva substitutes or of electro-stimulating devices. Although there are promising approaches to improve salivary gland function, most studies are characterized by small numbers and heterogeneous methods. Conclusions Physicians and dentists should identify the medications associated with xerostomia and salivary gland dysfunction through a thorough medical history. Preferably, health care providers should measure the unstimulated and stimulated whole salivary flow rates of all their patients so that these values can be used as a baseline to rate the complaints of patients who subsequently claim to experience xerostomia or salivary gland dysfunction as well as the possibilities of effectively treating this condition. Clinical relevance MISGD remains a major burden for the population. This systematic review provides a contemporary in-depth description of the diagnosis and treatment of MISGD.
650	7	a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Odontologi0 (SwePub)302162 hsv//swe
650	7	a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Dentistry0 (SwePub)302162 hsv//eng
653		a Xerostomia
653		a Saliva
653		a Medications
653		a Salivary gland dysfunction
653		a PRIMARY SJOGRENS-SYNDROME
653		a DRUG-INDUCED XEROSTOMIA
653		a RAT PAROTID-GLAND
653		a INDUCED DRY MOUTH
653		a FLOW-RATES
653		a DOUBLE-BLIND
653		a PILOCARPINE TREATMENT
653		a CLINICAL-TRIAL
653		a PSYCHIATRIC-PATIENTS
653		a SUBJECTIVE REPORTS
653		a Dentistry
653		a Oral Surgery & Medicine
700	1	a Wolff, A.4 aut
700	1	a Aframian, D.4 aut
700	1	a Vissink, A.4 aut
700	1	a Ekström, Jörgen,d 1944u Gothenburg University,Göteborgs universitet,Institutionen för neurovetenskap och fysiologi, sektionen för farmakologi,Institute of Neuroscience and Physiology, Department of Pharmacology4 aut0 (Swepub:gu)xeksjo
700	1	a Proctor, G.4 aut
700	1	a McGowan, R.4 aut
700	1	a Narayana, N.4 aut
700	1	a Aliko, A.4 aut
700	1	a Sia, Y. W.4 aut
700	1	a Joshi, R. K.4 aut
700	1	a Jensen, S. B.4 aut
700	1	a Kerr, A. R.4 aut
700	1	a Dawes, C.4 aut
700	1	a Pedersen, A. M. L.4 aut
710	2	a Göteborgs universitetb Institutionen för neurovetenskap och fysiologi, sektionen för farmakologi4 org
773	0	t Clinical Oral Investigationsd : Springer Science and Business Media LLCg 19:7, s. 1563-1580q 19:7<1563-1580x 1432-6981x 1436-3771
856	4 8	u https://gup.ub.gu.se/publication/223145
856	4 8	u https://doi.org/10.1007/s00784-015-1488-2

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Av författaren/redakt...: Villa, A.; Wolff, A.; Aframian, D.; Vissink, A.; Ekström, Jörgen, ...; Proctor, G.; visa fler...; McGowan, R.; Narayana, N.; Aliko, A.; Sia, Y. W.; Joshi, R. K.; Jensen, S. B.; Kerr, A. R.; Dawes, C.; Pedersen, A. M. ...; visa färre...

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