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Sökning: WFRF:(Skoda Maximilian W.A.) > Lipoprotein ability...

LIBRIS Formathandbok  (Information om MARC21)
FältnamnIndikatorerMetadata
00007296naa a2200697 4500
001oai:DiVA.org:mau-18012
003SwePub
008200817s2020 | |||||||||||000 ||eng|
009oai:lup.lub.lu.se:71f6e14f-5153-48b6-9a7a-396cbc6a2358
0247 a https://urn.kb.se/resolve?urn=urn:nbn:se:mau:diva-180122 URI
0247 a https://doi.org/10.1016/j.bbalip.2020.1587692 DOI
0247 a https://lup.lub.lu.se/record/71f6e14f-5153-48b6-9a7a-396cbc6a23582 URI
040 a (SwePub)maud (SwePub)lu
041 a engb eng
042 9 SwePub
072 7a ref2 swepub-contenttype
072 7a art2 swepub-publicationtype
1001 a Waldie, Sarahu Malmö University,Malmö universitet,Institutionen för biomedicinsk vetenskap (BMV),Biofilms Research Center for Biointerfaces,Institut Laue-Langevin, 71 Avenue des Martyrs, 38042 Grenoble, Cedex 9, France4 aut0 (Swepub:mau)AI6416
2451 0a Lipoprotein ability to exchange and remove lipids from model membranes as a function of fatty acid saturation and presence of cholesterol.
264 1b Elsevier,c 2020
338 a electronic2 rdacarrier
520 a Lipoproteins play a central role in the development of atherosclerosis. High and low-density lipoproteins (HDL and LDL), known as 'good' and 'bad' cholesterol, respectively, remove and/or deposit lipids into the artery wall. Hence, insight into lipid exchange processes between lipoproteins and cell membranes is of particular importance in understanding the onset and development of cardiovascular disease. In order to elucidate the impact of phospholipid tail saturation and the presence of cholesterol in cell membranes on these processes, neutron reflection was employed in the present investigation to follow lipid exchange with both HDL and LDL against model membranes. Mirroring clinical risk factors for the development of atherosclerosis, lower exchange was observed in the presence of cholesterol, as well as for an unsaturated phospholipid, compared to faster exchange when using a fully saturated phospholipid. These results highlight the importance of membrane composition on the interaction with lipoproteins, chiefly the saturation level of the lipids and presence of cholesterol, and provide novel insight into factors of importance for build-up and reversibility of atherosclerotic plaque. In addition, the correlation between the results and well-established clinical risk factors suggests that the approach taken can be employed also for understanding a broader set of risk factors including, e.g., effects of triglycerides and oxidative stress, as well as local effects of drugs on atherosclerotic plaque formation.
650 7a NATURVETENSKAPx Biologix Biokemi och molekylärbiologi0 (SwePub)106022 hsv//swe
650 7a NATURAL SCIENCESx Biological Sciencesx Biochemistry and Molecular Biology0 (SwePub)106022 hsv//eng
650 7a MEDICIN OCH HÄLSOVETENSKAPx Medicinska och farmaceutiska grundvetenskaperx Cell- och molekylärbiologi0 (SwePub)301082 hsv//swe
650 7a MEDICAL AND HEALTH SCIENCESx Basic Medicinex Cell and Molecular Biology0 (SwePub)301082 hsv//eng
653 a Cholesterol
653 a Lipid removal
653 a Lipoproteins
653 a Neutron reflection
653 a Saturated fats
653 a Cholesterol
653 a Lipid removal
653 a Lipoproteins
653 a Neutron reflection
653 a Saturated fats
7001 a Sebastiani, Federicau Malmö University,Malmö universitet,Institutionen för biomedicinsk vetenskap (BMV),Biofilms Research Center for Biointerfaces4 aut0 (Swepub:mau)ai3677
7001 a Browning, Kathrynu Department of Pharmacy, Copenhagen University, Universitetsparken 2, 2100 Copenhagen, Denmark4 aut
7001 a Maric, Selmau Lund University,Lunds universitet,MAX IV-laboratoriet,MAX IV Laboratory4 aut0 (Swepub:lu)se5447ma
7001 a Lind, Tania Ku Malmö University,Malmö universitet,Institutionen för biomedicinsk vetenskap (BMV),Biofilms Research Center for Biointerfaces4 aut0 (Swepub:lu)extLU-82
7001 a Yepuri, Nageshwaru National Deuteration Facility, Australian Nuclear Science and Technology Organisation, New Illawarra Road, Lucas Heights, NSW 2234, Australia4 aut
7001 a Darwish, Tamim Au National Deuteration Facility, Australian Nuclear Science and Technology Organisation, New Illawarra Road, Lucas Heights, NSW 2234, Australia4 aut
7001 a Moulin, Martineu Institut Laue-Langevin, 71 Avenue des Martyrs, 38042 Grenoble, Cedex 9, France4 aut
7001 a Strohmeier, Gernotu Austrian Centre of Industrial Biotechnology, Petersgasse 14, 8010 Graz, Austria; Graz University of Technology, Institute of Organic Chemistry, NAWI Graz, Stremayrgasse 9, 8010 Graz, Austria,Austrian Center of Industrial Biotechnology GmbH4 aut
7001 a Pichler, Haraldu Austrian Centre of Industrial Biotechnology, Petersgasse 14, 8010 Graz, Austria; Graz University of Technology, Institute of Molecular Biotechnology, NAWI Graz, BioTechMed Graz, Petersgasse 14, 8010 Graz, Austria,Austrian Center of Industrial Biotechnology GmbH4 aut
7001 a Skoda, Maximilian W Au STFC, Rutherford Appleton Laboratory, ISIS, Harwell, Didcot OX11 0QX, UK4 aut
7001 a Maestro, Armandou Institut Laue-Langevin, 71 Avenue des Martyrs, 38042 Grenoble, Cedex 9, France4 aut
7001 a Haertlein, Michaelu Institut Laue-Langevin, 71 Avenue des Martyrs, 38042 Grenoble, Cedex 9, France4 aut
7001 a Forsyth, V Trevoru Institut Laue-Langevin, 71 Avenue des Martyrs, 38042 Grenoble, Cedex 9, France; Faculty of Natural Sciences, Keele University, Staffordshire ST5 5BG, UK4 aut
7001 a Bengtsson, Evau Lund University,Lunds universitet,Kardiovaskulär forskning - matrix och inflammation i ateroskleros,Forskargrupper vid Lunds universitet,Cardiovascular Research - Matrix and Inflammation in Atherosclerosis,Lund University Research Groups4 aut0 (Swepub:lu)medf-eb0
7001 a Malmsten, Martinu Lund University,Lunds universitet,Fysikalisk kemi,Enheten för fysikalisk och teoretisk kemi,Kemiska institutionen,Institutioner vid LTH,Lunds Tekniska Högskola,Physical Chemistry,Physical and theoretical chemistry,Department of Chemistry,Departments at LTH,Faculty of Engineering, LTH,University of Copenhagen4 aut0 (Swepub:lu)ma1014ma
7001 a Cárdenas, Maritéu Malmö University,Malmö universitet,Institutionen för biomedicinsk vetenskap (BMV),Biofilms Research Center for Biointerfaces4 aut0 (Swepub:lu)fk1-mca
7102 a Malmö universitetb Institutionen för biomedicinsk vetenskap (BMV)4 org
7730 t Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipidsd : Elsevierg 1865:10q 1865:10x 1388-1981x 1879-2618
8564 u https://doi.org/10.1016/j.bbalip.2020.158769y Fulltext
8564 u https://mau.diva-portal.org/smash/get/diva2:1458633/FULLTEXT01.pdfx primaryx Raw objecty fulltext:print
8564 u https://doi.org/10.1016/j.bbalip.2020.158769
8564 u http://dx.doi.org/10.1016/j.bbalip.2020.158769x freey FULLTEXT
8564 8u https://urn.kb.se/resolve?urn=urn:nbn:se:mau:diva-18012
8564 8u https://doi.org/10.1016/j.bbalip.2020.158769
8564 8u https://lup.lub.lu.se/record/71f6e14f-5153-48b6-9a7a-396cbc6a2358

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