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Adherence to lifestyle advice and its related cardiovascular disease risk among US adults with high cholesterol

Guo, Jie (författare)
Stockholms universitet,Centrum för forskning om äldre och åldrande (ARC), (tills m KI)
Sun, Qing (författare)
Wu, Chaohui (författare)
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Wu, Jin (författare)
Karolinska Institutet,Stockholms universitet,Centrum för forskning om äldre och åldrande (ARC), (tills m KI)
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 (creator_code:org_t)
Elsevier BV, 2022
2022
Engelska.
Ingår i: Clinical Nutrition ESPEN. - : Elsevier BV. - 2405-4577. ; 51, s. 267-273
  • Tidskriftsartikel (refereegranskat)
Abstract Ämnesord
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  • Background & aims: Little is known about adherence to lifestyle advice from health professionals among people with high blood cholesterol, and its relationship with cardiovascular disease (CVD). We aimed to examine the proportion of adherence to lifestyle advice and its effect on lipid profile and CVD among people with high cholesterol. Methods: Within the National Health and Nutrition Examination Survey 1999–2010, the study included adults aged ≥20 years who were recommended to improve lifestyles in diet (N = 6645), bodyweight (N = 4797), or exercise (N = 5594) due to their high cholesterol. Adherent status was self-reported through questionnaires. Lipid measurements were collected from laboratory tests. 10-year Atherosclerotic CVD (ASCVD) risk was estimated by using pooled cohort risk equations for participants aged 40–79 years. CVD mortality up to December 31, 2019 was obtained from the National Death Index. Results: The percentages of adherents were 80.9%, 80.7%, and 72.7% for eating less fat, controlling weight, and increasing exercise, respectively. The percentages of adherents for controlling weight and increasing exercise significantly increased from 1999 to 2000 to 2009–2010 (both P trend <0.05). Adherents had a higher high-density lipoprotein cholesterol (HDL-C) and lower total cholesterol/HDL-C ratio than non-adherents (P for difference <0.05 for all). Participants adhering to increasing exercise had a lower odds ratio of 10-year intermediate-to-high ASCVD risk (Odd ratio 0.73, 95% confidence interval [CI] 0.56–0.95) and a lower CVD mortality (Hazard ratio 0.70, 95% CI 0.51–0.97) than non-adherents. Conclusions: Lifestyle advice from health staff obtained relatively high and increasing acceptability. Given the better lipid profile and lower CVD risk of adherents, health professionals should be encouraged to recommend lifestyle modifications for adults with high cholesterol in clinical practice. 

Ämnesord

MEDICIN OCH HÄLSOVETENSKAP  -- Hälsovetenskap -- Folkhälsovetenskap, global hälsa, socialmedicin och epidemiologi (hsv//swe)
MEDICAL AND HEALTH SCIENCES  -- Health Sciences -- Public Health, Global Health, Social Medicine and Epidemiology (hsv//eng)

Nyckelord

Adherence
Cholesterol
CVD mortality
Lifestyle modification
high density lipoprotein cholesterol
low density lipoprotein cholesterol
adult
cardiovascular disease
human
hypercholesterolemia
lifestyle
nutrition
primary prevention
Cardiovascular Diseases
Cholesterol
HDL
Cholesterol
LDL
Humans
Life Style
Nutrition Surveys

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Av författaren/redakt...
Guo, Jie
Sun, Qing
Wu, Chaohui
Wu, Jin
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MEDICIN OCH HÄLSOVETENSKAP
MEDICIN OCH HÄLS ...
och Hälsovetenskap
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Av lärosätet
Stockholms universitet
Karolinska Institutet

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