SwePub
Sök i LIBRIS databas

  Utökad sökning

WFRF:(De Bellis A)
 

Sökning: WFRF:(De Bellis A) > Management of cardi...

Management of cardiovascular complications in Klinefelter syndrome patients

Accardo, G. (författare)
Amoresano Paglionico, V. (författare)
Di Fraia, R. (författare)
visa fler...
Cittadini, A. (författare)
Salzano, A. (författare)
Esposito, Daniela (författare)
Gothenburg University,Göteborgs universitet,Institutionen för medicin, avdelningen för invärtesmedicin och klinisk nutrition,Institute of Medicine, Department of Internal Medicine and Clinical Nutrition
De Bellis, A. (författare)
Pasquali, D. (författare)
visa färre...
 (creator_code:org_t)
2019-02-22
2019
Engelska.
Ingår i: Expert Review of Endocrinology and Metabolism. - : Informa UK Limited. - 1744-6651 .- 1744-8417. ; 14:2, s. 145-152
Relaterad länk:
https://gup.ub.gu.se...
visa fler...
https://doi.org/10.1...
visa färre...
  • Tidskriftsartikel (refereegranskat)
Abstract Ämnesord
Stäng  
  • Introduction: Klinefelter syndrome (KS), also known as 47, XXY, shows increased mortality when compared with mortality rates among the general population. Cardiovascular, hemostatic, metabolic diseases are implicated. Moreover, cardiac congenital anomalies in KS can contribute to the increase in mortality. Areas covered: In this study, we have systematically reviewed the relationships between KS and the cardiovascular system and the management of cardiovascular complication. In summary, patients with KS display increased cardiovascular risk profile, characterized by increased prevalence of metabolic alterations including dyslipidemia, diabetes mellitus (DM), and abnormalities in biomarkers of cardiovascular disease. KS subjects are characterized by subclinical abnormalities in endothelial function and in left ventricular (LV) systolic and diastolic function, which–when associated with chronotropic incompetence–may negatively influence cardiopulmonary performance. Moreover, KS patients appear to be at a higher risk for cardiovascular disease, due to thromboembolic events with high prevalence of recurrent venous ulcers, venous insufficiency, recurrent venous and arterial thromboembolism leading to deep venous thrombosis or pulmonary embolism. Expert opinion: Considering the unequivocal finding of increased mortality of KS patients, we suggest a periodic cardiovascular follow up in specialized centers with multidisciplinary care teams that comprise endocrinologists and cardiologists dedicated to KS syndrome. © 2019, © 2019 Informa UK Limited, trading as Taylor & Francis Group.

Ämnesord

MEDICIN OCH HÄLSOVETENSKAP  -- Klinisk medicin -- Endokrinologi och diabetes (hsv//swe)
MEDICAL AND HEALTH SCIENCES  -- Clinical Medicine -- Endocrinology and Diabetes (hsv//eng)

Nyckelord

cardiovascular disease
intima-media thickness
Klinefelter
metabolic syndrome
platelet reactivity
testosterone
biological marker
androgen therapy
arterial thromboembolism
arterial wall thickness
Article
cardiovascular malformation
cardiovascular risk
cardiovascular system
cerebrovascular disease
chronotropism
deep vein thrombosis
diabetes mellitus
dyslipidemia
endothelial progenitor cell
heart left ventricle
human
Klinefelter syndrome
leg ulcer
lung embolism
male
oxygen consumption
prevalence
priority journal
QTc interval
risk factor
thromboembolism
ulcer
vein insufficiency

Publikations- och innehållstyp

ref (ämneskategori)
art (ämneskategori)

Hitta via bibliotek

Till lärosätets databas

Kungliga biblioteket hanterar dina personuppgifter i enlighet med EU:s dataskyddsförordning (2018), GDPR. Läs mer om hur det funkar här.
Så här hanterar KB dina uppgifter vid användning av denna tjänst.

 
pil uppåt Stäng

Kopiera och spara länken för att återkomma till aktuell vy