WFRF:(Günther Torsten)
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| Fältnamn | Indikatorer | Metadata |
|---|---|---|
| 000 | 04094naa a2200481 4500 | |
| 001 | oai:DiVA.org:uu-207313 | |
| 003 | SwePub | |
| 008 | 130912s2010 | |||||||||||000 ||eng| | |
| 009 | oai:slubar.slu.se:59988 | |
| 024 | 7 | a https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-2073132 URI |
| 024 | 7 | a https://doi.org/10.1186/1471-2164-11-1882 DOI |
| 024 | 7 | a https://res.slu.se/id/publ/599882 URI |
| 040 | a (SwePub)uud (SwePub)slu | |
| 041 | a engb eng | |
| 042 | 9 SwePub | |
| 072 | 7 | a ref2 swepub-contenttype |
| 072 | 7 | a art2 swepub-publicationtype |
| 100 | 1 | a Childs, Liam H4 aut |
| 245 | 1 0 | a Single feature polymorphism (SFP)-based selective sweep identification and association mapping of growth-related metabolic traits in Arabidopsis thaliana. |
| 264 | 1 | b Springer Science and Business Media LLC,c 2010 |
| 338 | a print2 rdacarrier | |
| 520 | a BACKGROUND: Natural accessions of Arabidopsis thaliana are characterized by a high level of phenotypic variation that can be used to investigate the extent and mode of selection on the primary metabolic traits. A collection of 54 A. thaliana natural accession-derived lines were subjected to deep genotyping through Single Feature Polymorphism (SFP) detection via genomic DNA hybridization to Arabidopsis Tiling 1.0 Arrays for the detection of selective sweeps, and identification of associations between sweep regions and growth-related metabolic traits.RESULTS: A total of 1,072,557 high-quality SFPs were detected and indications for 3,943 deletions and 1,007 duplications were obtained. A significantly lower than expected SFP frequency was observed in protein-, rRNA-, and tRNA-coding regions and in non-repetitive intergenic regions, while pseudogenes, transposons, and non-coding RNA genes are enriched with SFPs. Gene families involved in plant defence or in signalling were identified as highly polymorphic, while several other families including transcription factors are depleted of SFPs. 198 significant associations between metabolic genes and 9 metabolic and growth-related phenotypic traits were detected with annotation hinting at the nature of the relationship. Five significant selective sweep regions were also detected of which one associated significantly with a metabolic trait.CONCLUSIONS: We generated a high density polymorphism map for 54 A. thaliana accessions that highlights the variability of resistance genes across geographic ranges and used it to identify selective sweeps and associations between metabolic genes and metabolic phenotypes. Several associations show a clear biological relationship, while many remain requiring further investigation. | |
| 650 | 7 | a NATURVETENSKAPx Biologix Evolutionsbiologi0 (SwePub)106152 hsv//swe |
| 650 | 7 | a NATURAL SCIENCESx Biological Sciencesx Evolutionary Biology0 (SwePub)106152 hsv//eng |
| 650 | 7 | a NATURVETENSKAPx Biologix Genetik0 (SwePub)106092 hsv//swe |
| 650 | 7 | a NATURAL SCIENCESx Biological Sciencesx Genetics0 (SwePub)106092 hsv//eng |
| 650 | 7 | a NATURVETENSKAPx Biologix Botanik0 (SwePub)106072 hsv//swe |
| 650 | 7 | a NATURAL SCIENCESx Biological Sciencesx Botany0 (SwePub)106072 hsv//eng |
| 700 | 1 | a Witucka-Wall, Hanna4 aut |
| 700 | 1 | a Günther, Torsten4 aut |
| 700 | 1 | a Sulpice, Ronan4 aut |
| 700 | 1 | a Korff, Maria V4 aut |
| 700 | 1 | a Stitt, Mark4 aut |
| 700 | 1 | a Walther, Dirk4 aut |
| 700 | 1 | a Schmid, Karlu Swedish University of Agricultural Sciences,Sveriges lantbruksuniversitet,Institutionen för växtbiologi,Department of Plant Biology4 aut0 (Swepub:slu)49773 |
| 700 | 1 | a Altmann, Thomas4 aut |
| 710 | 2 | a Sveriges lantbruksuniversitetb Institutionen för växtbiologi4 org |
| 710 | 2 | a Sveriges lantbruksuniversitet |
| 773 | 0 | t BMC Genomicsd : Springer Science and Business Media LLCg 11, s. 188-q 11<188-x 1471-2164 |
| 856 | 4 | u https://bmcgenomics.biomedcentral.com/track/pdf/10.1186/1471-2164-11-188 |
| 856 | 4 8 | u https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-207313 |
| 856 | 4 8 | u https://doi.org/10.1186/1471-2164-11-188 |
| 856 | 4 8 | u https://res.slu.se/id/publ/59988 |
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