Late-onset sepsis among extremely preterm infants of 24-28 weeks gestation: an international comparison in 10 high-income countries

↓ Direkt till sidans innehåll
↓ Direkt till sidans sekundära innehåll (sidomenyn)

Search: WFRF:(Lehtonen Liisa) > Late-onset sepsis a...

Late-onset sepsis among extremely preterm infants of 24-28 weeks gestation : an international comparison in 10 high-income countries

Klinger, Gil (author): Department of Neonatal Intensive Care, Schneider Children's Medical Center of Israel, Petah Tikva, Israel; School of Medicine, Tel Aviv University, Tel Aviv, Israel

Reichman, Brian (author): School of Medicine, Tel Aviv University, Tel Aviv, Israel; Women and Children's Health Research Unit, Gertner Institute, Chaim Sheba Medical Center, Tel Hashomer, Israel

Norman, Mikael (author): Karolinska Institutet, Department of Clinical Science, Intervention, and Technology, Stockholm, Sweden; Department of Neonatal Medicine, Karolinska University Hospital, Stockholm, Sweden

Kusuda, Satoshi (author): Department of Pediatrics, Kyorin University, Tokyo, Japan

Battin, Malcolm (author): Newborn Service, Te Whatu Ora, Te Toka Tumai, Auckland, New Zealand

Helenius, Kjell (author): Department of Paediatrics and Adolescent Medicine, Turku University Hospital, Turku, Finland; Department of Medicine, University of Turku, Turku, Finland

Isayama, Tetsuya (author): Division of Neonatology, National Center for Child Health and Development, Tokyo, Japan

Lui, Kei (author): Department of Newborn Care, Royal Hospital for Women and School of Women's and Children's Health, Faculty of Medicine, University of New South Wales, NSW, Sydney, Australia

Adams, Mark (author): Newborn Research, Department of Neonatology, University of Zurich, University Hospital Zurich, Zurich, Switzerland

Vento, Maximo (author): Instituto de Investigación Sanitaria (Health Research Institute) La Fe Valencia, Valencia, Spain

Håkansson, Stellan (author): Umeå universitet,Pediatrik

Beltempo, Marc (author): Department of Pediatrics, McGill University, QC, Montreal, Canada

Poggi, Chiara (author): Neonatal Intensive Care Unit, Department of Mother and Child Care, Careggi University Hospital, Florence, Italy

San Feliciano, Laura (author): Unidad de Neonatología, Hospital Universitario de Salamanca, Salamanca, Spain

Lehtonen, Liisa (author): Department of Paediatrics and Adolescent Medicine, Turku University Hospital, Turku, Finland; Department of Medicine, University of Turku, Turku, Finland

Bassler, Dirk (author): Department of Newborn Care, Royal Hospital for Women and School of Women's and Children's Health, Faculty of Medicine, University of New South Wales, NSW, Sydney, Australia

Yang, Junmin (author): Department of Pediatrics, Mount Sinai Hospital, University of Toronto, ON, Toronto, Canada

Shah, Prakesh S. (author): Department of Pediatrics, Mount Sinai Hospital, University of Toronto, ON, Toronto, Canada

show less...

(creator_code:org_t)

2024
2024
English.
In: Neonatology. - : S. Karger. - 1661-7800 .- 1661-7819.

Related links:: https://doi.org/10.1...; show more...; https://umu.diva-por... (primary) (Raw object); https://urn.kb.se/re...; https://doi.org/10.1...; show less...

Journal article (peer-reviewed)

Abstract Subject headings

Introduction: Despite advances in neonatal care, late-onset sepsis remains an important cause of preventable morbidity and mortality. Neonatal late-onset sepsis rates have decreased in some countries, while in others they have not. Our objective was to compare trends in late-onset sepsis rates in 9 population-based networks from 10 countries and to assess the associated mortality within 7 days of late-onset sepsis.Methods: We performed a retrospective populationbased cohort study. Infants born at 24-28 weeks' gestation between 2007 and 2019 were eligible for inclusion. Lateonset sepsis was defined as a positive blood or cerebrospinal fluid culture. Late-onset sepsis rates were calculated for 3 epochs (2007-11, 2012-15, and 2016-19). Adjusted risk ratios (aRRs) for late-onset sepsis were calculated for each network.Results: Of a total of 82,850 infants, 16,914 (20.4%) had late-onset sepsis, with Japan having the lowest rate (7.1%) and Spain the highest (44.6%). Late-onset sepsis rates decreased in most networks and remained unchanged in a few. Israel, Sweden, and Finland showed the largest decrease in late-onset sepsis rates. The aRRs for late-onset sepsis showed wide variations between networks. The rate of mortality temporally related to late-onset sepsis was 10.9%. The adjusted mean length of stay for infants with late-onset sepsis was increased by 5-18 days compared to infants with no late-onset sepsis.Conclusions: One in 5 neonates of 24-28 weeks' gestation develops late-onset sepsis. Wide variability in late-onset sepsis rates exists between networks with most networks exhibiting improvement. Late-onset sepsis was associated with increased mortality and length of stay.

Find in a library

Neonatology (Search for host publication in LIBRIS)

To the university's database

Find more in SwePub

About the subject

MEDICAL AND HEALTH SCIENCES: MEDICAL AND HEAL ...; and Clinical Medicin ...; and Pediatrics

Articles in the publication: Neonatology

By the university: Umeå University

Search outside SwePub

Extend your search to:: Google; Google Book Search; Google Scholar

Kungliga biblioteket hanterar dina personuppgifter i enlighet med EU:s dataskyddsförordning (2018), GDPR. Läs mer om hur det funkar här.
Så här hanterar KB dina uppgifter vid användning av denna tjänst.

LIBRIS.kb.se

Late-onset sepsis among extremely preterm infants of 24-28 weeks gestation : an international comparison in 10 high-income countries

Subject headings

Keyword

Publication and Content Type

Find in a library

To the university's database

Find more in SwePub

Search outside SwePub