Activation domain-mediated targeting of the SWI/SNF complex to promoters stimulates transcription from nucleosome arrays

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Fältnamn	Indikatorer	Metadata
000		02610naa a2200361 4500
001		oai:DiVA.org:sh-35663
003		SwePub
008		180625s1999 \| \|\|\|\|\|\|\|\|\|\|\|000 \|\|eng\|
024	7	a https://urn.kb.se/resolve?urn=urn:nbn:se:sh:diva-356632 URI
024	7	a https://doi.org/10.1016/S1097-2765(00)80216-62 DOI
040		a (SwePub)sh
041		a engb eng
042		9 SwePub
072	7	a ref2 swepub-contenttype
072	7	a art2 swepub-publicationtype
100	1	a Neely, K Eu Pennsylvania State University, Pennsylvania, USA4 aut
245	1 0	a Activation domain-mediated targeting of the SWI/SNF complex to promoters stimulates transcription from nucleosome arrays
264	1	c 1999
338		a print2 rdacarrier
520		a The yeast SWI/SNF complex is required for the transcription of several yeast genes and has been shown to alter nucleosome structure in an ATP-dependent reaction. In this study, we show that the complex stimulated in vitro transcription from nucleosome templates in an activation domain-dependent manner. Transcription stimulation by SWI/SNF required an activation domain with which it directly interacts. The acidic activation domains of VP16, Gcn4, Swi5, and Hap4 interacted directly with the purified SWI/SNF complex and with the SWI/SNF complex in whole-cell extracts. The similarity of activation domain interactions and transcriptional stimulation between SWI/SNF and the SAGA histone acetyltransferase complex may account for their apparent overlapping functions in vivo.
650	7	a NATURVETENSKAPx Biologi0 (SwePub)1062 hsv//swe
650	7	a NATURAL SCIENCESx Biological Sciences0 (SwePub)1062 hsv//eng
700	1	a Hassan, A Hu Pennsylvania State University, Pennsylvania, USA4 aut
700	1	a Wallberg, Annika Eu Södertörns högskola,Avdelning Naturvetenskap,Karolinska Institutet4 aut
700	1	a Steger, D Ju Pennsylvania State University, Pennsylvania, USA4 aut
700	1	a Cairns, B Ru University of Utah School of Medicine, Salt Lake City, USA4 aut
700	1	a Wright, Athony P Hu Södertörns högskola,Avdelning Naturvetenskap,Karolinska Institutet4 aut0 (Swepub:sh)SHAYWT
700	1	a Workman, J Lu Pennsylvania State University, Pennsylvania, USA4 aut
710	2	a Pennsylvania State University, Pennsylvania, USAb Avdelning Naturvetenskap4 org
773	0	t Molecular Cellg 4:4, s. 649-655q 4:4<649-655x 1097-2765x 1097-4164
856	4	u https://doi.org/10.1016/S1097-2765(00)80216-6y Fulltext
856	4 8	u https://urn.kb.se/resolve?urn=urn:nbn:se:sh:diva-35663
856	4 8	u https://doi.org/10.1016/S1097-2765(00)80216-6

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Av författaren/redakt...: Neely, K E; Hassan, A H; Wallberg, Annika ...; Steger, D J; Cairns, B R; Wright, Athony P ...; visa fler...; Workman, J L; visa färre...

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