A comprehensive 1000 Genomes-based genome-wide association meta-analysis of coronary artery disease

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Fältnamn	Indikatorer	Metadata
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024	7	a https://lup.lub.lu.se/record/82215732 URI
024	7	a https://doi.org/10.1038/ng.33962 DOI
024	7	a http://kipublications.ki.se/Default.aspx?queryparsed=id:1321129582 URI
024	7	a https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-2656942 URI
040		a (SwePub)lud (SwePub)kid (SwePub)uu
041		a engb eng
042		9 SwePub
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100	1	a Nikpay, Majidu Univ Ottawa, Inst Heart, Ruddy Canadian Cardiovasc Genet Ctr, Ottawa, ON, Canada.4 aut
245	1 0	a A comprehensive 1000 Genomes-based genome-wide association meta-analysis of coronary artery disease
264		c 2015-09-07
264	1	b Springer Science and Business Media LLC,c 2015
520		a Existing knowledge of genetic variants affecting risk of coronary artery disease (CAD) is largely based on genome-wide association study (GWAS) analysis of common SNPs. Leveraging phased haplotypes from the 1000 Genomes Project, we report a GWAS meta-analysis of similar to 185,000 CAD cases and controls, interrogating 6.7 million common (minor allele frequency (MAF) > 0.05) and 2.7 million low-frequency (0.005 < MAF < 0.05) variants. In addition to confirming most known CAD-associated loci, we identified ten new loci (eight additive and two recessive) that contain candidate causal genes newly implicating biological processes in vessel walls. We observed intralocus allelic heterogeneity but little evidence of low-frequency variants with larger effects and no evidence of synthetic association. Our analysis provides a comprehensive survey of the fine genetic architecture of CAD, showing that genetic susceptibility to this common disease is largely determined by common SNPs of small effect size.
650	7	a MEDICIN OCH HÄLSOVETENSKAPx Medicinska och farmaceutiska grundvetenskaperx Medicinsk genetik0 (SwePub)301072 hsv//swe
650	7	a MEDICAL AND HEALTH SCIENCESx Basic Medicinex Medical Genetics0 (SwePub)301072 hsv//eng
650	7	a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Kardiologi0 (SwePub)302062 hsv//swe
650	7	a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Cardiac and Cardiovascular Systems0 (SwePub)302062 hsv//eng
700	1	a Goel, Anuju Univ Oxford, Div Cardiovasc Med, Radcliffe Dept Med, Oxford, England.;Univ Oxford, Wellcome Trust Ctr Human Genet, Oxford, England.4 aut
700	1	a Won, Hong-Heeu Broad Inst MIT & Harvard Univ, Cambridge, MA USA.;Massachusetts Gen Hosp, Cardiovasc Res Ctr, Boston, MA 02114 USA.;Massachusetts Gen Hosp, Ctr Human Genet Res, Boston, MA 02114 USA.;Harvard Univ, Sch Med, Dept Med, Boston, MA USA.4 aut
700	1	a Hall, Leanne M.u Univ Leicester, Dept Cardiovasc Sci, Leicester, Leics, England.4 aut
700	1	a Willenborg, Christinau Univ Lubeck, Inst Integrat & Expt Genom, Lubeck, Germany.;DZHK German Res Ctr Cardiovasc Res, Lubeck, Germany.4 aut
700	1	a Kanoni, Stavroulau Queen Mary Univ London, Barts & London Sch Med & Dent, William Harvey Res Inst, London, England.4 aut
700	1	a Saleheen, Danishu Univ Penn, Perelman Sch Med, Philadelphia, PA 19104 USA.;Ctr Noncommunicable Dis, Karachi, Pakistan.4 aut
700	1	a Kyriakou, Theodosiosu Univ Oxford, Div Cardiovasc Med, Radcliffe Dept Med, Oxford, England.;Univ Oxford, Wellcome Trust Ctr Human Genet, Oxford, England.4 aut
700	1	a Nelson, Christopher P.u Univ Leicester, Dept Cardiovasc Sci, Leicester, Leics, England.;Glenfield Hosp, NIHR, Leicester Cardiovasc Biomed Res Unit, Leicester, Leics, England.4 aut
700	1	a Hopewell, Jemma C.u Univ Oxford, Nuffield Dept Populat Hlth, Clin Trial Serv Unit, Oxford, England.;Univ Oxford, Nuffield Dept Populat Hlth, Epidemiol Studies Unit CTSU, Oxford, England.4 aut
700	1	a Webb, Thomas R.u Univ Leicester, Dept Cardiovasc Sci, Leicester, Leics, England.;Glenfield Hosp, NIHR, Leicester Cardiovasc Biomed Res Unit, Leicester, Leics, England.,Univ Ottawa, Inst Heart, Ottawa, ON, Canada.4 aut
700	1	a Zeng, Lingyaou Tech Univ Munich, Deutsches Herzzentrum Munchen, D-80290 Munich, Germany.;DZHK German Ctr Cardiovasc Res, Munich, Germany.4 aut
700	1	a Dehghan, Abbasu Erasmus Univ, Med Ctr, Dept Epidemiol, Rotterdam, Netherlands.4 aut
700	1	a Alver, Marisu Univ Tartu, Estonian Genome Ctr, EE-50090 Tartu, Estonia.;Univ Tartu, Inst Mol & Cell Biol, EE-50090 Tartu, Estonia.4 aut
700	1	a Armasu, Sebastian M.u Mayo Clin, Dept Hlth Sci Res, Div Biomed Stat & Informat, Rochester, MN USA.4 aut
700	1	a Auro, Kirsiu Natl Inst Hlth & Welf, Dept Hlth, Helsinki, Finland.;Univ Helsinki, Inst Mol Med Finland FIMM, Helsinki, Finland.;Univ Helsinki, Diabet & Obes Res Program, Helsinki, Finland.4 aut
700	1	a Bjonnes, Andrewu Broad Inst MIT & Harvard Univ, Cambridge, MA USA.;Massachusetts Gen Hosp, Ctr Human Genet Res, Boston, MA 02114 USA.4 aut
700	1	a Chasman, Daniel I.u Brigham & Womens Hosp, Div Prevent Med, Boston, MA 02115 USA.;Harvard Univ, Sch Med, Boston, MA USA.4 aut
700	1	a Chen, Shufengu Chinese Acad Med Sci, Natl Ctr Cardiovasc Dis, Fuwai Hosp, State Key Lab Cardiovasc Dis, Beijing 100730, Peoples R China.;Peking Union Med Coll, Beijing 100021, Peoples R China.4 aut
700	1	a Ford, Ianu Univ Glasgow, Robertson Ctr Biostat, Glasgow, Lanark, Scotland.4 aut
700	1	a Franceschini, Norau Univ N Carolina, Dept Epidemiol, Gillings Sch Global Publ Hlth, Chapel Hill, NC USA.4 aut
700	1	a Gieger, Christianu DZHK German Ctr Cardiovasc Res, Munich, Germany.;German Res Ctr Environm Hlth, Helmholtz Zentrum Munchen, Inst Epidemiol 2, Neuherberg, Germany.;German Res Ctr Environm Hlth, Helmholtz Zentrum Munchen, Res Unit Mol Epidemiol, Neuherberg, Germany.4 aut
700	1	a Grace, Christopheru Univ Oxford, Div Cardiovasc Med, Radcliffe Dept Med, Oxford, England.;Univ Oxford, Wellcome Trust Ctr Human Genet, Oxford, England.4 aut
700	1	a Gustafsson, Stefanu Uppsala universitet,Molekylär epidemiologi,Science for Life Laboratory, SciLifeLab4 aut0 (Swepub:uu)stegu732
700	1	a Huang, Jieu Wellcome Trust Sanger Inst, Hinxton, England.4 aut
700	1	a Hwang, Shih-Jenu NHLBI, Framingham Heart Study, Framingham, MA USA.;Boston Univ, Sch Publ Hlth, Dept Biostat, Boston, MA USA.4 aut
700	1	a Kim, Yun Kyoungu Korea Natl Inst Hlth, Ctr Genome Sci, Chungcheongbuk Do, South Korea.4 aut
700	1	a Kleber, Marcus E.u Heidelberg Univ, Med Fac Mannheim, Vth Dept Med Nephrol Hypertensiol Endocrinol Diab, Mannheim, Germany.4 aut
700	1	a Lau, King Waiu Univ Oxford, Nuffield Dept Populat Hlth, Clin Trial Serv Unit, Oxford, England.;Univ Oxford, Nuffield Dept Populat Hlth, Epidemiol Studies Unit CTSU, Oxford, England.4 aut
700	1	a Lu, Xiangfengu Chinese Acad Med Sci, Natl Ctr Cardiovasc Dis, Fuwai Hosp, State Key Lab Cardiovasc Dis, Beijing 100730, Peoples R China.;Peking Union Med Coll, Beijing 100021, Peoples R China.4 aut
700	1	a Lu, Yingchangu Icahn Sch Med Mt Sinai, Charles Bronfman Inst Personalized Med, New York, NY 10029 USA.;Icahn Sch Med Mt Sinai, Genet Obes & Related Metab Traits Program, New York, NY 10029 USA.4 aut
700	1	a Lyytikainen, Leo-Pekkau Fimlab Labs, Dept Clin Chem, Tampere, Finland.;Univ Tampere, Sch Med, Dept Clin Chem, FIN-33101 Tampere, Finland.4 aut
700	1	a Mihailov, Evelinu Univ Tartu, Estonian Genome Ctr, EE-50090 Tartu, Estonia.4 aut
700	1	a Morrison, Alanna C.u Univ Texas Hlth Sci Ctr Houston, Human Genet Ctr, Sch Publ Hlth, Houston, TX 77030 USA.4 aut
700	1	a Pervjakova, Nataliau Univ Tartu, Estonian Genome Ctr, EE-50090 Tartu, Estonia.;Natl Inst Hlth & Welf, Dept Hlth, Helsinki, Finland.;Univ Helsinki, Inst Mol Med Finland FIMM, Helsinki, Finland.;Univ Helsinki, Diabet & Obes Res Program, Helsinki, Finland.4 aut
700	1	a Qu, Limingu Univ Penn, Dept Biostat & Epidemiol, Philadelphia, PA 19104 USA.4 aut
700	1	a Rose, Lynda M.u Brigham & Womens Hosp, Div Prevent Med, Boston, MA 02115 USA.4 aut
700	1	a Salfati, Eliasu Stanford Univ, Dept Med, Div Cardiovasc Med, Stanford, CA 94305 USA.4 aut
700	1	a Saxena, Richau Broad Inst MIT & Harvard Univ, Cambridge, MA USA.;Massachusetts Gen Hosp, Ctr Human Genet Res, Boston, MA 02114 USA.;Harvard Univ, Massachusetts Gen Hosp, Sch Med, Dept Anesthesia Crit Care & Pain Med, Boston, MA USA.4 aut
700	1	a Scholz, Markusu Univ Leipzig, Fac Med, Inst Med Informat Stat & Epidemiol, D-04109 Leipzig, Germany.;LIFE Res Ctr Civilizat Dis, Leipzig, Germany.,Univ Helsinki, Cent Hosp, Dept Med, Dept Cardiol, Helsinki, Finland.4 aut
700	1	a Smith, Albert V.u Iceland Heart Assoc, Kopavogur, Iceland.;Univ Iceland, Fac Med, Reykjavik, Iceland.4 aut
700	1	a Tikkanen, Emmiu Univ Helsinki, Inst Mol Med Finland FIMM, Helsinki, Finland.;Univ Helsinki, Dept Publ Hlth, Helsinki, Finland.4 aut
700	1	a Uitterlinden, Andreu Erasmus Univ, Med Ctr, Dept Epidemiol, Rotterdam, Netherlands.4 aut
700	1	a Yang, Xueliu Chinese Acad Med Sci, Natl Ctr Cardiovasc Dis, Fuwai Hosp, State Key Lab Cardiovasc Dis, Beijing 100730, Peoples R China.;Peking Union Med Coll, Beijing 100021, Peoples R China.4 aut
700	1	a Zhang, Weihuau Univ London Imperial Coll Sci Technol & Med, Dept Epidemiol & Biostat, London, England.;Ealing Hosp Natl Hlth Serv NHS Trust, Dept Cardiol, Southall, Middx, England.4 aut
700	1	a Zhao, Weiu Univ Penn, Perelman Sch Med, Philadelphia, PA 19104 USA.4 aut
700	1	a de Andrade, Marizau Mayo Clin, Dept Hlth Sci Res, Div Biomed Stat & Informat, Rochester, MN USA.4 aut
700	1	a de Vries, Paul S.u Erasmus Univ, Med Ctr, Dept Epidemiol, Rotterdam, Netherlands.4 aut
700	1	a van Zuydam, Natalie R.u Univ Oxford, Wellcome Trust Ctr Human Genet, Oxford, England.;Univ Dundee, Med Res Inst, Dundee, Scotland.4 aut
700	1	a Anand, Sonia S.u McMaster Univ, Dept Med, Populat Hlth Res Inst, Hamilton Hlth Sci, Hamilton, ON, Canada.4 aut
700	1	a Bertram, Larsu Univ Lubeck, Inst Neurogenet & Integrat, Platform Genome Analyt, Lubeck, Germany.;Univ Lubeck, Inst Expt Gen, Platform Genome Analyt, Lubeck, Germany.;Univ London Imperial Coll Sci Technol & Med, Fac Med, Sch Publ Hlth, Neuroepidemiol & Ageing Res Unit, London, England.4 aut
700	1	a Beutner, Franku LIFE Res Ctr Civilizat Dis, Leipzig, Germany.;Univ Leipzig, Heart Ctr Leipzig, Cardiol, D-04109 Leipzig, Germany.4 aut
700	1	a Dedoussis, Georgeu Harokopio Univ, Dept Dietet Nutr, Athens, Greece.4 aut
700	1	a Frossard, Philippeu Ctr Noncommunicable Dis, Karachi, Pakistan.4 aut
700	1	a Gauguier, Dominiqueu INSERM, Ctr Rech Cordeliers, UMRS 1138, Paris, France.4 aut
700	1	a Goodall, Alison H.u Karolinska Institutet,Glenfield Hosp, NIHR, Leicester Cardiovasc Biomed Res Unit, Leicester, Leics, England.;Univ Leicester, Glenfield Hosp, Dept Cardiovasc Sci, Leicester, Leics, England.4 aut
700	1	a Gottesman, Omriu Icahn Sch Med Mt Sinai, Charles Bronfman Inst Personalized Med, New York, NY 10029 USA.4 aut
700	1	a Haber, Marcu Lebanese Amer Univ, Sch Med, Beirut, Lebanon.4 aut
700	1	a Han, Bok-Gheeu Korea Natl Inst Hlth, Ctr Genome Sci, Chungcheongbuk Do, South Korea.4 aut
700	1	a Huang, Jianfengu Peking Union Med Coll, Beijing 100021, Peoples R China.;Chinese Acad Med Sci, Natl Ctr Cardiovasc Dis, Fuwai Hosp, Hypertens Div, Beijing 100730, Peoples R China.4 aut
700	1	a Jalilzadeh, Shapouru Univ Oxford, Div Cardiovasc Med, Radcliffe Dept Med, Oxford, England.;Univ Oxford, Wellcome Trust Ctr Human Genet, Oxford, England.4 aut
700	1	a Kessler, Thorstenu Tech Univ Munich, Deutsches Herzzentrum Munchen, D-80290 Munich, Germany.;Klinikum Rechts Der Isar, Munich, Germany.4 aut
700	1	a Koenig, Inke R.u DZHK German Res Ctr Cardiovasc Res, Lubeck, Germany.;Univ Lubeck, Inst Med Biometrie & Stat, Lubeck, Germany.4 aut
700	1	a Lannfelt, Larsu Uppsala universitet,Karolinska Institutet,Geriatrik,Karolinska Inst, Dept Med Epidemiol & Biostat, Stockholm, Sweden.,NHLBI, Framingham Heart Study, Framingham, MA USA.;Boston Univ, Sch Publ Hlth, Dept Biostat, Boston, MA USA.,Cleveland Clin, Dept Cellular & Mol Med, Cleveland, OH 44106 USA.,Stanford Univ, Dept Med, Div Cardiovasc Med, Stanford, CA 94305 USA.;Stanford Univ, Stanford Cardiovasc Inst, Stanford, CA 94305 USA.4 aut0 (Swepub:uu)lalan021
700	1	a Lieb, Wolfgangu Univ Kiel, Inst Epidemiol, Kiel, Germany.4 aut
700	1	a Lind, Larsu Uppsala universitet,Kardiovaskulär epidemiologi4 aut0 (Swepub:uu)larslind
700	1	a Lindgren, Cecilia M.u Univ Oxford, Wellcome Trust Ctr Human Genet, Oxford, England.;Broad Inst MIT & Harvard Univ, Cambridge, MA USA.4 aut
700	1	a Lokki, Marja-Liisau Univ Helsinki, Haartman Inst, Transplantat Lab, Helsinki, Finland.4 aut
700	1	a Magnusson, Patrik K.u Karolinska Institutet,Karolinska Inst, Dept Med Epidemiol & Biostat, Stockholm, Sweden.4 aut
700	1	a Mallick, Nadeem H.u Punjab Inst Cardiol, Lahore, Pakistan.4 aut
700	1	a Mehra, Narinderu All India Inst Med Sci, New Delhi, India.4 aut
700	1	a Meitinger, Thomasu DZHK German Ctr Cardiovasc Res, Munich, Germany.;German Res Ctr Environm Hlth, Helmholtz Zentrum Munchen, Inst Humangenet, Neuherberg, Germany.;Tech Univ Munich, Inst Human Genet, D-80290 Munich, Germany.4 aut
700	1	a Memon, Fazal-ur-Rehmanu Red Crescent Inst Cardiol, Hyderabad, Andhra Pradesh, Pakistan.4 aut
700	1	a Morris, Andrew P.u Univ Oxford, Wellcome Trust Ctr Human Genet, Oxford, England.;Univ Liverpool, Dept Biostat, Liverpool L69 3BX, Merseyside, England.4 aut
700	1	a Nieminen, Markku S.4 aut
700	1	a Pedersen, Nancy L.4 aut
700	1	a Peters, Annetteu DZHK German Ctr Cardiovasc Res, Munich, Germany.;German Res Ctr Environm Hlth, Helmholtz Zentrum Munchen, Inst Epidemiol 2, Neuherberg, Germany.4 aut
700	1	a Rallidis, Loukianos S.u Univ Athens, Sch Med, Attikon Hosp, Dept Cardiol 2, GR-11527 Athens, Greece.4 aut
700	1	a Rasheed, Asifu Ctr Noncommunicable Dis, Karachi, Pakistan.;Red Crescent Inst Cardiol, Hyderabad, Andhra Pradesh, Pakistan.4 aut
700	1	a Samuel, Mariau Ctr Noncommunicable Dis, Karachi, Pakistan.4 aut
700	1	a Shah, Svati H.u Duke Univ, Med Ctr, Dept Med, Durham, NC 27710 USA.,Univ Leeds, Leeds Inst Genet Hlth & Therapeut, Leeds, W Yorkshire, England.4 aut
700	1	a Sinisalo, Juhau Univ Helsinki, Cent Hosp, Dept Med, Dept Cardiol, Helsinki, Finland.4 aut
700	1	a Stirrups, Kathleen E.u Queen Mary Univ London, Barts & London Sch Med & Dent, William Harvey Res Inst, London, England.;Univ Cambridge, Dept Haematol, Cambridge, England.4 aut
700	1	a Trompet, Stellau Leiden Univ, Med Ctr, Dept Cardiol, Leiden, Netherlands.;Leiden Univ, Med Ctr, Dept Gerontol & Geriatr, Leiden, Netherlands.4 aut
700	1	a Wang, Laiyuanu Chinese Acad Med Sci, Natl Ctr Cardiovasc Dis, Fuwai Hosp, State Key Lab Cardiovasc Dis, Beijing 100730, Peoples R China.;Peking Union Med Coll, Beijing 100021, Peoples R China.;Natl Human Genome Ctr Beijing, Beijing, Peoples R China.4 aut
700	1	a Zaman, Khan S.u Natl Inst Cardiovasc Dis, Karachi, Pakistan.4 aut
700	1	a Ardissino, Diegou Univ Parma, Azienda Osped, Div Cardiol, I-43100 Parma, Italy.;Assoc Studio Trombosi Cardiol, Pavia, Italy.4 aut
700	1	a Boerwinkle, Ericu Univ Texas Hlth Sci Ctr Houston, Human Genet Ctr, Sch Publ Hlth, Houston, TX 77030 USA.;Baylor Coll Med, Human Genome Sequencing Ctr, Houston, TX 77030 USA.4 aut
700	1	a Borecki, Ingrid B.u Washington Univ, Sch Med, Dept Genet, St Louis, MO 63110 USA.4 aut
700	1	a Bottinger, Erwin P.u Icahn Sch Med Mt Sinai, Charles Bronfman Inst Personalized Med, New York, NY 10029 USA.4 aut
700	1	a Buring, Julie E.u Brigham & Womens Hosp, Div Prevent Med, Boston, MA 02115 USA.4 aut
700	1	a Chambers, John C.u Univ London Imperial Coll Sci Technol & Med, Dept Epidemiol & Biostat, London, England.;Ealing Hosp Natl Hlth Serv NHS Trust, Dept Cardiol, Southall, Middx, England.;Imperial Coll Healthcare NHS Trust, London, England.4 aut
700	1	a Collins, Roryu Univ Oxford, Nuffield Dept Populat Hlth, Clin Trial Serv Unit, Oxford, England.;Univ Oxford, Nuffield Dept Populat Hlth, Epidemiol Studies Unit CTSU, Oxford, England.4 aut
700	1	a Cupples, L. Adrienne4 aut
700	1	a Danesh, Johnu Wellcome Trust Sanger Inst, Hinxton, England.;Univ Cambridge, Dept Publ Hlth & Primary Care, Cambridge, England.4 aut
700	1	a Demuth, Iljau Berlin Aging Study 2, Berlin, Germany.;Charite, Res Grp Geriatr, D-13353 Berlin, Germany.;Charite, Inst Med & Human Genet, D-13353 Berlin, Germany.4 aut
700	1	a Elosua, Robertou Inst Hosp Mar Invest Med IMIM, Grp Epidemiol & Genet Cardiovasc, Barcelona, Spain.4 aut
700	1	a Epstein, Stephen E.u MedStar Washington Hosp Ctr, MedStar Heart & Vasc Inst, Washington, DC USA.4 aut
700	1	a Esko, Tonuu Broad Inst MIT & Harvard Univ, Cambridge, MA USA.;Univ Tartu, Estonian Genome Ctr, EE-50090 Tartu, Estonia.;Boston Childrens Hosp, Div Endocrinol & Basic & Translat Obes Res, Boston, MA USA.;Harvard Univ, Sch Med, Dept Genet, Boston, MA USA.4 aut
700	1	a Feitosa, Mary F.u Washington Univ, Sch Med, Dept Genet, St Louis, MO 63110 USA.4 aut
700	1	a Franco, Oscar H.u Erasmus Univ, Med Ctr, Dept Epidemiol, Rotterdam, Netherlands.4 aut
700	1	a Franzosi, Maria Graziau IRCCS Ist Ric Farmacol Mario Negri, Dept Cardiovasc Res, Milan, Italy.4 aut
700	1	a Granger, Christopher B.u Duke Univ, Med Ctr, Dept Med, Durham, NC 27710 USA.4 aut
700	1	a Gu, Dongfengu Chinese Acad Med Sci, Natl Ctr Cardiovasc Dis, Fuwai Hosp, State Key Lab Cardiovasc Dis, Beijing 100730, Peoples R China.;Peking Union Med Coll, Beijing 100021, Peoples R China.4 aut
700	1	a Gudnason, Vilmunduru Iceland Heart Assoc, Kopavogur, Iceland.;Univ Iceland, Fac Med, Reykjavik, Iceland.4 aut
700	1	a Hall, Alistair S.4 aut
700	1	a Hamsten, Andersu Karolinska Inst, Dept Med Solna, Atherosclerosis Res Unit, Cardiovasc Genet & Genom Grp, Stockholm, Sweden.4 aut
700	1	a Harris, Tamara B.u NIA, Lab Epidemiol Demog & Biometry, US Natl Inst Hlth, Bethesda, MD 20892 USA.4 aut
700	1	a Hazen, Stanley L.4 aut
700	1	a Hengstenberg, Christianu Tech Univ Munich, Deutsches Herzzentrum Munchen, D-80290 Munich, Germany.;DZHK German Ctr Cardiovasc Res, Munich, Germany.4 aut
700	1	a Hofman, Albertu Erasmus Univ, Med Ctr, Dept Epidemiol, Rotterdam, Netherlands.4 aut
700	1	a Ingelsson, Eriku Uppsala universitet,Molekylär epidemiologi,Science for Life Laboratory, SciLifeLab,Univ Oxford, Wellcome Trust Ctr Human Genet, Oxford, England.;Stanford Univ, Dept Med, Div Cardiovasc Med, Stanford, CA 94305 USA.4 aut0 (Swepub:uu)ering425
700	1	a Iribarren, Carlosu Kaiser Permanente Div Res, Oakland, CA USA.4 aut
700	1	a Jukema, J. Wouteru Leiden Univ, Med Ctr, Dept Cardiol, Leiden, Netherlands.;Durrer Ctr Cardiogenet Res, Amsterdam, Netherlands.;Interunivers Cardiol Inst Netherlands, Utrecht, Netherlands.4 aut
700	1	a Karhunen, Pekka J.u Fimlab Labs, Dept Clin Chem, Tampere, Finland.;Univ Tampere, Sch Med, Dept Forens Med, FIN-33101 Tampere, Finland.4 aut
700	1	a Kim, Bong-Jou Korea Natl Inst Hlth, Ctr Genome Sci, Chungcheongbuk Do, South Korea.4 aut
700	1	a Kooner, Jaspal S.u Ealing Hosp Natl Hlth Serv NHS Trust, Dept Cardiol, Southall, Middx, England.;Imperial Coll Healthcare NHS Trust, London, England.;Univ London Imperial Coll Sci Technol & Med, Natl Heart & Lung Inst, Cardiovasc Sci, London, England.4 aut
700	1	a Kullo, Iftikhar J.u Mayo Clin, Dept Med, Cardiovasc Dis, Rochester, MN USA.4 aut
700	1	a Lehtimaki, Terhou Fimlab Labs, Dept Clin Chem, Tampere, Finland.;Univ Tampere, Sch Med, Dept Clin Chem, FIN-33101 Tampere, Finland.4 aut
700	1	a Loos, Ruth J. F.u Icahn Sch Med Mt Sinai, Charles Bronfman Inst Personalized Med, New York, NY 10029 USA.;Icahn Sch Med Mt Sinai, Genet Obes & Related Metab Traits Program, New York, NY 10029 USA.;Icahn Sch Med Mt Sinai, Mindich Child Hlth & Dev Inst, New York, NY 10029 USA.4 aut
700	1	a Melander, Olleu Lund University,Lunds universitet,Kardiovaskulär forskning - hypertoni,Forskargrupper vid Lunds universitet,Cardiovascular Research - Hypertension,Lund University Research Groups,Lund Univ, Univ Hosp Malmo, Dept Clin Sci Hypertens & Cardiovasc Dis, Malmo, Sweden.4 aut0 (Swepub:lu)endo-ome
700	1	a Metspalu, Andresu Univ Tartu, Estonian Genome Ctr, EE-50090 Tartu, Estonia.;Univ Tartu, Inst Mol & Cell Biol, EE-50090 Tartu, Estonia.4 aut
700	1	a Maerz, Winfriedu Heidelberg Univ, Med Fac Mannheim, Vth Dept Med Nephrol Hypertensiol Endocrinol Diab, Mannheim, Germany.;Synlab Acad, Synlab Serv, Mannheim, Germany.;Med Univ Graz, Clin Inst Med & Chem Lab Diagnost, Graz, Austria.4 aut
700	1	a Palmer, Colin N.u Univ Dundee, Med Res Inst, Dundee, Scotland.4 aut
700	1	a Perola, Markusu Univ Tartu, Estonian Genome Ctr, EE-50090 Tartu, Estonia.;Natl Inst Hlth & Welf, Dept Hlth, Helsinki, Finland.;Univ Helsinki, Inst Mol Med Finland FIMM, Helsinki, Finland.;Univ Helsinki, Diabet & Obes Res Program, Helsinki, Finland.4 aut
700	1	a Quertermous, Thomasu Stanford Univ, Dept Med, Div Cardiovasc Med, Stanford, CA 94305 USA.;Stanford Univ, Stanford Cardiovasc Inst, Stanford, CA 94305 USA.4 aut
700	1	a Rader, Daniel J.u Univ Penn, Perelman Sch Med, Dept Genet, Philadelphia, PA 19104 USA.;Univ Penn, Perelman Sch Med, Cardiovasc Inst, Philadelphia, PA 19104 USA.4 aut
700	1	a Ridker, Paul M.u Brigham & Womens Hosp, Div Prevent Med, Boston, MA 02115 USA.;Harvard Univ, Sch Med, Boston, MA USA.4 aut
700	1	a Ripatti, Samuliu Univ Helsinki, Inst Mol Med Finland FIMM, Helsinki, Finland.;Wellcome Trust Sanger Inst, Hinxton, England.;Univ Helsinki, Dept Publ Hlth, Helsinki, Finland.4 aut
700	1	a Roberts, Robertu Univ Leicester, Dept Hlth Sci, Leicester, Leics, England.,Univ Oxford, Nuffield Dept Populat Hlth, Clin Trial Serv Unit, Oxford, England.;Univ Oxford, Nuffield Dept Populat Hlth, Epidemiol Studies Unit CTSU, Oxford, England.4 aut
700	1	a Salomaa, Veikkou Natl Inst Hlth & Welf, Dept Chron Dis Prevent, Helsinki, Finland.4 aut
700	1	a Sanghera, Dharambir K.u Univ Oklahoma, Hlth Sci Ctr, Dept Pediat, Coll Med, Oklahoma City, OK 73190 USA.;Univ Oklahoma, Hlth Sci Ctr, Coll Pharm, Dept Pharmaceut Sci, Oklahoma City, OK 73190 USA.;Oklahoma Ctr Neurosci, Oklahoma City, OK USA.4 aut
700	1	a Schwartz, Stephen M.u Fred Hutchinson Canc Res Ctr, Publ Hlth Sci Div, Seattle, WA 98104 USA.;Univ Washington, Dept Epidemiol, Seattle, WA 98195 USA.4 aut
700	1	a Seedorf, Udou Univ Med Ctr Hamburg Eppendorf, Ctr Dent & Oral Med, Dept Prosthet Dent, Hamburg, Germany.4 aut
700	1	a Stewart, Alexandre F.u Univ Ottawa, Inst Heart, Ruddy Canadian Cardiovasc Genet Ctr, Ottawa, ON, Canada.4 aut
700	1	a Stott, David J.u Univ Glasgow, Fac Med, Inst Cardiovasc & Med Sci, Glasgow, Lanark, Scotland.4 aut
700	1	a Thiery, Joachimu LIFE Res Ctr Civilizat Dis, Leipzig, Germany.;Univ Hosp Leipzig, Fac Med, Inst Lab Med Clin Chem & Mol Diagnost, Leipzig, Germany.4 aut
700	1	a Zalloua, Pierre A.u Lebanese Amer Univ, Sch Med, Beirut, Lebanon.;Harvard Univ, Sch Publ Hlth, Boston, MA 02115 USA.4 aut
700	1	a O'Donnell, Christopher J.u NHLBI, Framingham Heart Study, Framingham, MA USA.;NHLBI, Div Intramural Res, Bethesda, MD 20892 USA.;Massachusetts Gen Hosp, Cardiol Div, Boston, MA 02114 USA.4 aut
700	1	a Reilly, Muredach P.4 aut
700	1	a Assimes, Themistocles L.4 aut
700	1	a Thompson, John R.4 aut
700	1	a Erdmann, Jeanetteu Univ Lubeck, Inst Integrat & Expt Genom, Lubeck, Germany.;DZHK German Res Ctr Cardiovasc Res, Lubeck, Germany.4 aut
700	1	a Clarke, Robert4 aut
700	1	a Watkins, Hughu Univ Oxford, Div Cardiovasc Med, Radcliffe Dept Med, Oxford, England.;Univ Oxford, Wellcome Trust Ctr Human Genet, Oxford, England.4 aut
700	1	a Kathiresan, Sekaru Broad Inst MIT & Harvard Univ, Cambridge, MA USA.;Massachusetts Gen Hosp, Cardiovasc Res Ctr, Boston, MA 02114 USA.;Massachusetts Gen Hosp, Ctr Human Genet Res, Boston, MA 02114 USA.;Harvard Univ, Sch Med, Dept Med, Boston, MA USA.4 aut
700	1	a McPherson, Ruthu Univ Ottawa, Inst Heart, Ruddy Canadian Cardiovasc Genet Ctr, Ottawa, ON, Canada.4 aut
700	1	a Deloukas, Panosu Queen Mary Univ London, Barts & London Sch Med & Dent, William Harvey Res Inst, London, England.;King Abdulaziz Univ, Princess Al Jawhara Al Brahim Ctr Excellence Res, Jeddah 21413, Saudi Arabia.4 aut
700	1	a Schunkert, Heribertu Tech Univ Munich, Deutsches Herzzentrum Munchen, D-80290 Munich, Germany.;DZHK German Ctr Cardiovasc Res, Munich, Germany.4 aut
700	1	a Samani, Nilesh J.u Univ Leicester, Dept Cardiovasc Sci, Leicester, Leics, England.;Glenfield Hosp, NIHR, Leicester Cardiovasc Biomed Res Unit, Leicester, Leics, England.4 aut
700	1	a Farrall, Martinu Univ Oxford, Div Cardiovasc Med, Radcliffe Dept Med, Oxford, England.;Univ Oxford, Wellcome Trust Ctr Human Genet, Oxford, England.4 aut
710	2	a Univ Ottawa, Inst Heart, Ruddy Canadian Cardiovasc Genet Ctr, Ottawa, ON, Canada.b Univ Oxford, Div Cardiovasc Med, Radcliffe Dept Med, Oxford, England.;Univ Oxford, Wellcome Trust Ctr Human Genet, Oxford, England.4 org
773	0	t Nature Geneticsd : Springer Science and Business Media LLCg 47:10, s. 1121-1121q 47:10<1121-1121x 1546-1718x 1061-4036
856	4	u http://dx.doi.org/10.1038/ng.3396y FULLTEXT
856	4	u https://discovery.dundee.ac.uk/ws/files/7268983/CAD1000G2015.pdf
856	4 8	u https://lup.lub.lu.se/record/8221573
856	4 8	u https://doi.org/10.1038/ng.3396
856	4 8	u http://kipublications.ki.se/Default.aspx?queryparsed=id:132112958
856	4 8	u https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-265694

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By the author/editor: Nikpay, Majid; Goel, Anuj; Won, Hong-Hee; Hall, Leanne M.; Willenborg, Chri ...; Kanoni, Stavroul ...; show more...; Saleheen, Danish; Kyriakou, Theodo ...; Nelson, Christop ...; Hopewell, Jemma ...; Webb, Thomas R.; Zeng, Lingyao; Dehghan, Abbas; Alver, Maris; Armasu, Sebastia ...; Auro, Kirsi; Bjonnes, Andrew; Chasman, Daniel ...; Chen, Shufeng; Ford, Ian; Franceschini, No ...; Gieger, Christia ...; Grace, Christoph ...; Gustafsson, Stef ...; Huang, Jie; Hwang, Shih-Jen; Kim, Yun Kyoung; Kleber, Marcus E ...; Lau, King Wai; Lu, Xiangfeng; Lu, Yingchang; Lyytikainen, Leo ...; Mihailov, Evelin; Morrison, Alanna ...; Pervjakova, Nata ...; Qu, Liming; Rose, Lynda M.; Salfati, Elias; Saxena, Richa; Scholz, Markus; Smith, Albert V.; Tikkanen, Emmi; Uitterlinden, An ...; Yang, Xueli; Zhang, Weihua; Zhao, Wei; de Andrade, Mari ...; de Vries, Paul S ...; van Zuydam, Nata ...; Anand, Sonia S.; Bertram, Lars; Beutner, Frank; Dedoussis, Georg ...; Frossard, Philip ...; Gauguier, Domini ...; Goodall, Alison ...; Gottesman, Omri; Haber, Marc; Han, Bok-Ghee; Huang, Jianfeng; Jalilzadeh, Shap ...; Kessler, Thorste ...; Koenig, Inke R.; Lannfelt, Lars; Lieb, Wolfgang; Lind, Lars; Lindgren, Cecili ...; Lokki, Marja-Lii ...; Magnusson, Patri ...; Mallick, Nadeem ...; Mehra, Narinder; Meitinger, Thoma ...; Memon, Fazal-ur- ...; Morris, Andrew P ...; Nieminen, Markku ...; Pedersen, Nancy ...; Peters, Annette; Rallidis, Loukia ...; Rasheed, Asif; Samuel, Maria; Shah, Svati H.; Sinisalo, Juha; Stirrups, Kathle ...; Trompet, Stella; Wang, Laiyuan; Zaman, Khan S.; Ardissino, Diego; Boerwinkle, Eric; Borecki, Ingrid ...; Bottinger, Erwin ...; Buring, Julie E.; Chambers, John C ...; Collins, Rory; Cupples, L. Adri ...; Danesh, John; Demuth, Ilja; Elosua, Roberto; Epstein, Stephen ...; Esko, Tonu; Feitosa, Mary F.; Franco, Oscar H.; Franzosi, Maria ...; Granger, Christo ...; Gu, Dongfeng; Gudnason, Vilmun ...; Hall, Alistair S ...; Hamsten, Anders; Harris, Tamara B ...; Hazen, Stanley L ...; Hengstenberg, Ch ...; Hofman, Albert; Ingelsson, Erik; Iribarren, Carlo ...; Jukema, J. Woute ...; Karhunen, Pekka ...; Kim, Bong-Jo; Kooner, Jaspal S ...; Kullo, Iftikhar ...; Lehtimaki, Terho; Loos, Ruth J. F.; Melander, Olle; Metspalu, Andres; Maerz, Winfried; Palmer, Colin N.; Perola, Markus; Quertermous, Tho ...; Rader, Daniel J.; Ridker, Paul M.; Ripatti, Samuli; Roberts, Robert; Salomaa, Veikko; Sanghera, Dharam ...; Schwartz, Stephe ...; Seedorf, Udo; Stewart, Alexand ...; Stott, David J.; Thiery, Joachim; Zalloua, Pierre ...; O'Donnell, Chris ...; Reilly, Muredach ...; Assimes, Themist ...; Thompson, John R ...; Erdmann, Jeanett ...; Clarke, Robert; Watkins, Hugh; Kathiresan, Seka ...; McPherson, Ruth; Deloukas, Panos; Schunkert, Herib ...; Samani, Nilesh J ...; Farrall, Martin; show less...

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MEDICAL AND HEALTH SCIENCES: MEDICAL AND HEAL ...; and Basic Medicine; and Medical Genetics

MEDICAL AND HEALTH SCIENCES: MEDICAL AND HEAL ...; and Clinical Medicin ...; and Cardiac and Card ...

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