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WFRF:(Araujo Carlos M.)
 

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LIBRIS Formathandbok  (Information om MARC21)
FältnamnIndikatorerMetadata
00009903naa a2200925 4500
001oai:DiVA.org:uu-437450
003SwePub
008210312s2021 | |||||||||||000 ||eng|
0247 a https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-4374502 URI
0247 a https://doi.org/10.3390/ijerph180310152 DOI
040 a (SwePub)uu
041 a engb eng
042 9 SwePub
072 7a ref2 swepub-contenttype
072 7a art2 swepub-publicationtype
1001 a Amaral, Ritau Uppsala universitet,Pediatrisk inflammations- och metabolismforskning samt barnhälsa,Univ Porto, Fac Med, Ctr Hlth Technol & Serv Res CINTESIS, P-4200319 Porto, Portugal.;Univ Porto, Dept Community Med Informat & Hlth Decis Sci MEDC, Fac Med, P-4200319 Porto, Portugal.;Polytech Inst Porto, Porto Hlth Sch, Dept Cardiovasc & Resp Sci, P-4200072 Porto, Portugal.;Uppsala Univ, Dept Womens & Childrens Hlth, Paediat Res, SE-75105 Uppsala, Sweden.4 aut
2451 0a Profiling Persistent Asthma Phenotypes in Adolescents :b A Longitudinal Diagnostic Evaluation from the INSPIRERS Studies
264 c 2021-01-24
264 1b MDPI,c 2021
338 a electronic2 rdacarrier
520 a We aimed to identify persistent asthma phenotypes among adolescents and to evaluate longitudinally asthma-related outcomes across phenotypes. Adolescents (13-17 years) from the prospective, observational, and multicenter INSPIRERS studies, conducted in Portugal and Spain, were included (n = 162). Latent class analysis was applied to demographic, environmental, and clinical variables, collected at a baseline medical visit. Longitudinal differences in clinical variables were assessed at a 4-month follow-up telephone contact (n = 128). Three classes/phenotypes of persistent asthma were identified. Adolescents in class 1 (n = 87) were highly symptomatic at baseline and presented the highest number of unscheduled healthcare visits per month and exacerbations per month, both at baseline and follow-up. Class 2 (n = 32) was characterized by female predominance, more frequent obesity, and uncontrolled upper/lower airways symptoms at baseline. At follow-up, there was a significant increase in the proportion of controlled lower airway symptoms (p < 0.001). Class 3 (n = 43) included mostly males with controlled lower airways symptoms; at follow-up, while keeping symptom control, there was a significant increase in exacerbations/month (p = 0.015). We have identified distinct phenotypes of persistent asthma in adolescents with different patterns in longitudinal asthma-related outcomes, supporting the importance of profiling asthma phenotypes in predicting disease outcomes that might inform targeted interventions and reduce future risk.
650 7a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Lungmedicin och allergi0 (SwePub)302192 hsv//swe
650 7a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Respiratory Medicine and Allergy0 (SwePub)302192 hsv//eng
653 a asthma
653 a adolescents
653 a phenotypes
653 a clustering
653 a longitudinal studies
653 a latent class analysis
7001 a Jacome, Cristinau Univ Porto, Fac Med, Ctr Hlth Technol & Serv Res CINTESIS, P-4200319 Porto, Portugal.;Univ Porto, Dept Community Med Informat & Hlth Decis Sci MEDC, Fac Med, P-4200319 Porto, Portugal.4 aut
7001 a Almeida, Ruteu Univ Porto, Fac Med, Ctr Hlth Technol & Serv Res CINTESIS, P-4200319 Porto, Portugal.;Univ Porto, Dept Community Med Informat & Hlth Decis Sci MEDC, Fac Med, P-4200319 Porto, Portugal.4 aut
7001 a Pereira, Ana Margaridau Univ Porto, Fac Med, Ctr Hlth Technol & Serv Res CINTESIS, P-4200319 Porto, Portugal.;Univ Porto, Dept Community Med Informat & Hlth Decis Sci MEDC, Fac Med, P-4200319 Porto, Portugal.;CUF Porto Hosp & Inst, Allergy Unit, P-4100180 Porto, Portugal.4 aut
7001 a Alves-Correia, Magnau CUF Porto Hosp & Inst, Allergy Unit, P-4100180 Porto, Portugal.4 aut
7001 a Mendes, Sandrau Univ Porto, Fac Med, Ctr Hlth Technol & Serv Res CINTESIS, P-4200319 Porto, Portugal.4 aut
7001 a Rodrigues, Jose Carlos Cidraisu Hosp Pedro Hispano, Serv Pediat, Unidade Local Saude Matosinhos, P-4464513 Matosinhos, Portugal.4 aut
7001 a Carvalho, Joanau Hosp Pedro Hispano, Serv Pediat, Unidade Local Saude Matosinhos, P-4464513 Matosinhos, Portugal.4 aut
7001 a Araujo, Luisu CUF Porto Hosp & Inst, Allergy Unit, P-4100180 Porto, Portugal.4 aut
7001 a Costa, Albertou Hosp Senhora Oliveira, Serv Pediat, P-4835044 Guimaraes, Portugal.4 aut
7001 a Silva, Armandinau Hosp Senhora Oliveira, Serv Pediat, P-4835044 Guimaraes, Portugal.4 aut
7001 a Teixeira, Maria Fernandau Ctr Hosp Univ Porto, Ctr Materno Infantil Norte, Serv Pediat, P-4099001 Porto, Portugal.4 aut
7001 a Ferreira-Magalhaes, Manuelu Univ Porto, Dept Community Med Informat & Hlth Decis Sci MEDC, Fac Med, P-4200319 Porto, Portugal.;Ctr Hosp Univ Porto, Ctr Materno Infantil Norte, Serv Pediat, P-4099001 Porto, Portugal.4 aut
7001 a Alves, Rodrigo Rodriguesu Hosp Div Espirito Santo, Serv Imunoalergol, P-9500370 Ponta Delgada, Portugal.4 aut
7001 a Moreira, Ana Sofiau Hosp Divino Espirito Santo, Unidade Imunoalergol, P-9500370 Ponta Delgada, Portugal.4 aut
7001 a Fernandes, Ricardo M.u Ctr Hosp Lisboa Norte, Hosp Santa Maria, Dept Pediat, P-1649035 Lisbon, Portugal.4 aut
7001 a Ferreira, Rosariou Ctr Hosp Lisboa Norte, Hosp Santa Maria, Dept Pediat, P-1649035 Lisbon, Portugal.4 aut
7001 a Pinto, Paula Leiriau Ctr Hosp Univ Lisboa Cent, Hosp Dona Estefania, Serv Imunoalergol, P-1150199 Lisbon, Portugal.4 aut
7001 a Neuparth, Nunou Ctr Hosp Univ Lisboa Cent, Hosp Dona Estefania, Serv Imunoalergol, P-1150199 Lisbon, Portugal.;Nova Med Sch, CHRC CEDOC, Pathophysiol, P-1150190 Lisbon, Portugal.4 aut
7001 a Bordalo, Dianau Ctr Hosp Medio Ave, Unidade Hosp Famalicao, Serv Pediat, P-4780371 Vila Nova De Famalicao, Portugal.4 aut
7001 a Bom, Ana Todou Ctr Hosp & Univ Coimbra, Serv Imunoalergol, P-3000075 Coimbra, Portugal.4 aut
7001 a Calix, Maria Joseu Hosp Sao Teotonio, Ctr Hosp Tondela Viseu, Serv Pediat, P-3504509 Viseu, Portugal.4 aut
7001 a Ferreira, Taniau ACeS Baixo Mondego, Unidade Saude Familiar Progresso & Saude, P-3060716 Tocha, Portugal.4 aut
7001 a Gomes, Joanau Ctr Hosp Vila Nova Gaia Espinho, Unidade 1, Serv Imunoalergol, P-4434502 Vila Nova De Gaia, Portugal.4 aut
7001 a Vidal, Carmenu Complejo Hosp Univ Santiago, Serv Alergia, Santiago De Compostela 15706, Spain.4 aut
7001 a Mendes, Anau Ctr Hosp Lisboa Norte, Hosp Santa Maria, Dept Pediat, P-1649035 Lisbon, Portugal.4 aut
7001 a Vasconcelos, Maria Joaou Ctr Hosp Univ Sao Joao, Serv Imunoalergol, P-4200319 Porto, Portugal.4 aut
7001 a Silva, Pedro Moraisu Grp HPA Saude, Imunoalergol, P-8500322 Portimao, Portugal.4 aut
7001 a Ferraz, Joseu Hosp Privado Alfena, Imunoalergol, P-4445243 Trofa Saude, Alfena, Portugal.4 aut
7001 a Morete, Anau Hosp Infante D Pedro, Ctr Hosp Baixo Vouga, Serv Imunoalergol, P-3814501 Aveiro, Portugal.4 aut
7001 a Pinto, Claudia Sofiau Hosp Sao Pedro Vila Real, Ctr Hosp Tras Os Montes E Alto Douro, Serv Pneumol, P-5000508 Vila Real, Portugal.4 aut
7001 a Santos, Natachau Ctr Hosp Univ Algarve, Serv Imunoalergol, P-8000386 Portimao, Portugal.4 aut
7001 a Loureiro, Claudia Chavesu Hosp Univ Coimbra, Serv Pneumol, P-3000076 Coimbra, Portugal.4 aut
7001 a Arrobas, Anau Ctr Hosp & Univ Coimbra, Serv Pneumol, P-3000075 Coimbra, Portugal.4 aut
7001 a Marques, Maria Luisu Ctr Hosp Univ Porto, Serv Imunoalergol, P-4099001 Porto, Portugal.4 aut
7001 a Lozoya, Carlosu Hosp Amato Lusitano, Unidade Local Saude Castelo Branco, Serv Imunoalergol, P-6000085 Castelo Branco, Portugal.4 aut
7001 a Lopes, Cristinau Hosp Pedro Hispano, Serv Pediat, Unidade Local Saude Matosinhos, P-4464513 Matosinhos, Portugal.;Univ Porto, Fac Med, Imunol Basica & Clin, P-4200319 Porto, Portugal.4 aut
7001 a Cardia, Franciscau ACES Dao Lafoes, Unidade Saude Familiar Terras Azurara, P-3530113 Mangualde, Portugal.4 aut
7001 a Loureiro, Carla Chavesu Ctr Hosp & Univ Coimbra, Dept Pediat, Serv Pediat Ambulatoria, P-3000075 Coimbra, Portugal.4 aut
7001 a Camara, Raquelu Hosp Nossa Senhora Rosario, Ctr Hosp Barreiro Montijo, Serv Pneumol, P-2834003 Barreiro, Portugal.4 aut
7001 a Vieira, Inesu ACES Pinhal Litoral, UCSP Dr Arnaldo Sampaio, P-2419014 Leiria, Portugal.4 aut
7001 a da Silva, Sofiau USF Cuidarte, Unidade Local Saude Alto Minho, P-4925083 Portuzelo, Portugal.4 aut
7001 a Silva, Euricou ACeS Baixo Vouga, Unidade Saude Familiar Joao Semana, P-3880225 Ovar, Portugal.4 aut
7001 a Rodrigues, Natalinau ACES Baixo Mondego, Unidade Saude Familiar Mondego, P-3045059 Coimbra, Portugal.4 aut
7001 a Fonseca, Joao A.u Univ Porto, Fac Med, Ctr Hlth Technol & Serv Res CINTESIS, P-4200319 Porto, Portugal.;Univ Porto, Dept Community Med Informat & Hlth Decis Sci MEDC, Fac Med, P-4200319 Porto, Portugal.;CUF Porto Hosp & Inst, Allergy Unit, P-4100180 Porto, Portugal.4 aut
7102 a Uppsala universitetb Pediatrisk inflammations- och metabolismforskning samt barnhälsa4 org
7730 t International Journal of Environmental Research and Public Healthd : MDPIg 18:3q 18:3x 1661-7827x 1660-4601
8564 u https://doi.org/10.3390/ijerph18031015y Fulltext
8564 u https://uu.diva-portal.org/smash/get/diva2:1536774/FULLTEXT01.pdfx primaryx Raw objecty fulltext:print
8564 u https://www.mdpi.com/1660-4601/18/3/1015/pdf
8564 8u https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-437450
8564 8u https://doi.org/10.3390/ijerph18031015

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