SwePub
Sök i LIBRIS databas

  Utökad sökning

WFRF:(Lloyd Matthew T)
 

Sökning: WFRF:(Lloyd Matthew T) > Pathology reporting...

LIBRIS Formathandbok  (Information om MARC21)
FältnamnIndikatorerMetadata
00004233naa a2200529 4500
001oai:DiVA.org:uu-132769
003SwePub
008101026s2010 | |||||||||||000 ||eng|
0247 a https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-1327692 URI
0247 a https://doi.org/10.1097/PAS.0b013e3181ce14472 DOI
040 a (SwePub)uu
041 a engb eng
042 9 SwePub
072 7a ref2 swepub-contenttype
072 7a art2 swepub-publicationtype
1001 a Klimstra, David S.4 aut
2451 0a Pathology reporting of neuroendocrine tumors :b application of the Delphic consensus process to the development of a minimum pathology data set
264 1c 2010
338 a print2 rdacarrier
520 a Epithelial neuroendocrine tumors (NETs) have been the subject of much debate regarding their optimal classification. Although multiple systems of nomenclature, grading, and staging have been proposed, none has achieved universal acceptance. To help define the underlying common features of these classification systems and to identify the minimal pathology data that should be reported to ensure consistent clinical management and reproducibility of data from therapeutic trials, a multidisciplinary team of physicians interested in NETs was assembled. At a group meeting, the participants discussed a series of "yes" or "no" questions related to the pathology of NETs and the minimal data to be included in the reports. After discussion, anonymous votes were taken, using the Delphic principle that 80% agreement on a vote of either yes or no would define a consensus. Questions that failed to achieve a consensus were rephrased once or twice and discussed, and additional votes were taken. Of 108 questions, 91 were answerable either yes or no by more than 80% of the participants. There was agreement about the importance of proliferation rate for tumor grading, the landmarks to use for staging, the prognostic factors assessable by routine histology that should be reported, the potential for tumors to progress biologically with metastasis, and the current status of advanced immunohistochemical and molecular testing for treatment-related biomarkers. The lack of utility of a variety of immunohistochemical stains and pathologic findings was also agreed upon. A consensus could not be reached for the remaining 17 questions, which included both minor points related to extent of disease assessment and some major areas such as terminology, routine immunohistochemical staining for general neuroendocrine markers, use of Ki67 staining to assess proliferation, and the relationship of tumor grade to degree of differentiation. On the basis of the results of the Delphic voting, a minimum pathology data set was developed. Although there remains disagreement among experts about the specific classification system that should be used, there is agreement about the fundamental pathology data that should be reported. Examination of the areas of disagreement reveals significant opportunities for collaborative study to resolve unanswered questions.
653 a MEDICINE
653 a MEDICIN
7001 a Modlin, Irvin R.4 aut
7001 a Adsay, N. Volkan4 aut
7001 a Chetty, Runjan4 aut
7001 a Deshpande, Vikram4 aut
7001 a Gönen, Mithat4 aut
7001 a Jensen, Robert T.4 aut
7001 a Kidd, Mark4 aut
7001 a Kulke, Matthew H.4 aut
7001 a Lloyd, Ricardo V.4 aut
7001 a Moran, Cesar4 aut
7001 a Moss, Steven F.4 aut
7001 a Öberg, Kjellu Uppsala universitet,Medicin,Kjell Öberg4 aut0 (Swepub:uu)kjellob
7001 a O'Toole, Dermot4 aut
7001 a Rindi, Guido4 aut
7001 a Robert, Marie E.4 aut
7001 a Suster, Saul4 aut
7001 a Tang, Laura H.4 aut
7001 a Tzen, Chin-Yuan4 aut
7001 a Washington, Mary Kay4 aut
7001 a Wiedenmann, Betram4 aut
7001 a Yao, James4 aut
7102 a Uppsala universitetb Medicin4 org
7730 t American Journal of Surgical Pathologyg 34:3, s. 300-313q 34:3<300-313x 0147-5185x 1532-0979
8564 8u https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-132769
8564 8u https://doi.org/10.1097/PAS.0b013e3181ce1447

Hitta via bibliotek

Till lärosätets databas

Kungliga biblioteket hanterar dina personuppgifter i enlighet med EU:s dataskyddsförordning (2018), GDPR. Läs mer om hur det funkar här.
Så här hanterar KB dina uppgifter vid användning av denna tjänst.

 
pil uppåt Stäng

Kopiera och spara länken för att återkomma till aktuell vy