Sökning: WFRF:(B Carlborg) > Genome-Wide Effects...
Fältnamn | Indikatorer | Metadata |
---|---|---|
000 | 03448naa a2200457 4500 | |
001 | oai:DiVA.org:uu-147105 | |
003 | SwePub | |
008 | 110224s2010 | |||||||||||000 ||eng| | |
009 | oai:slubar.slu.se:60482 | |
024 | 7 | a https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-1471052 URI |
024 | 7 | a https://doi.org/10.1371/journal.pgen.10011882 DOI |
024 | 7 | a https://res.slu.se/id/publ/604822 URI |
040 | a (SwePub)uud (SwePub)slu | |
041 | a engb eng | |
042 | 9 SwePub | |
072 | 7 | a ref2 swepub-contenttype |
072 | 7 | a art2 swepub-publicationtype |
100 | 1 | a Johansson, Anna Mariau Swedish University of Agricultural Sciences,Sveriges lantbruksuniversitet,Institutionen för husdjursgenetik (HGEN),Department of Animal Breeding and Genetics4 aut0 (Swepub:slu)51108 |
245 | 1 0 | a Genome-Wide Effects of Long-Term Divergent Selection |
264 | c 2010-11-04 | |
264 | 1 | b Public Library of Science (PLoS),c 2010 |
338 | a print2 rdacarrier | |
520 | a To understand the genetic mechanisms leading to phenotypic differentiation, it is important to identify genomic regions under selection. We scanned the genome of two chicken lines from a single trait selection experiment, where 50 generations of selection have resulted in a 9-fold difference in body weight. Analyses of nearly 60,000 SNP markers showed that the effects of selection on the genome are dramatic. The lines were fixed for alternative alleles in more than 50 regions as a result of selection. Another 10 regions displayed strong evidence for ongoing differentiation during the last 10 generations. Many more regions across the genome showed large differences in allele frequency between the lines, indicating that the phenotypic evolution in the lines in 50 generations is the result of an exploitation of standing genetic variation at 100s of loci across the genome. | |
650 | 7 | a NATURVETENSKAPx Biologi0 (SwePub)1062 hsv//swe |
650 | 7 | a NATURAL SCIENCESx Biological Sciences0 (SwePub)1062 hsv//eng |
650 | 7 | a LANTBRUKSVETENSKAPERx Husdjursvetenskap0 (SwePub)4022 hsv//swe |
650 | 7 | a AGRICULTURAL SCIENCESx Animal and Dairy Sience0 (SwePub)4022 hsv//eng |
650 | 7 | a LANTBRUKSVETENSKAPERx Veterinärmedicin0 (SwePub)4032 hsv//swe |
650 | 7 | a AGRICULTURAL SCIENCESx Veterinary Science0 (SwePub)4032 hsv//eng |
653 | a Biology | |
653 | a Biologi | |
700 | 1 | a Pettersson, Matsu Swedish University of Agricultural Sciences,Sveriges lantbruksuniversitet,Institutionen för husdjursgenetik (HGEN),Department of Animal Breeding and Genetics4 aut0 (Swepub:slu)49767 |
700 | 1 | a Siegel, Paul B.4 aut |
700 | 1 | a Carlborg, Örjanu Swedish University of Agricultural Sciences,Sveriges lantbruksuniversitet,Uppsala universitet,Centrum för bioinformatik,Institutionen för kliniska vetenskaper (KV),Department of Clinical Sciences,Uppsala University4 aut0 (Swepub:slu)48083 |
710 | 2 | a Sveriges lantbruksuniversitetb Institutionen för husdjursgenetik (HGEN)4 org |
710 | 2 | a Sveriges lantbruksuniversitet |
773 | 0 | t PLoS Geneticsd : Public Library of Science (PLoS)g 6:11, s. e1001188-q 6:11<e1001188-x 1553-7390x 1553-7404 |
856 | 4 | u https://journals.plos.org/plosgenetics/article/file?id=10.1371/journal.pgen.1001188&type=printable |
856 | 4 8 | u https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-147105 |
856 | 4 8 | u https://doi.org/10.1371/journal.pgen.1001188 |
856 | 4 8 | u https://res.slu.se/id/publ/60482 |
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