Sökning: WFRF:(Lindkvist P.) > Helicobacter pylori...
Fältnamn | Indikatorer | Metadata |
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000 | 05095naa a2200985 4500 | |
001 | oai:lup.lub.lu.se:a5c05b9f-1603-4c2d-8f11-e90640884891 | |
003 | SwePub | |
008 | 160401s2012 | |||||||||||000 ||eng| | |
009 | oai:DiVA.org:umu-55667 | |
024 | 7 | a https://lup.lub.lu.se/record/25515692 URI |
024 | 7 | a https://doi.org/10.1093/annonc/mdr3842 DOI |
024 | 7 | a https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-556672 URI |
040 | a (SwePub)lud (SwePub)umu | |
041 | a engb eng | |
042 | 9 SwePub | |
072 | 7 | a art2 swepub-publicationtype |
072 | 7 | a ref2 swepub-contenttype |
100 | 1 | a Gonzalez, C. A.4 aut |
245 | 1 0 | a Helicobacter pylori infection assessed by ELISA and by immunoblot and noncardia gastric cancer risk in a prospective study: the Eurgast-EPIC project |
264 | 1 | b Elsevier BV,c 2012 |
520 | a In epidemiological studies, Helicobacter pylori infection is usually detected by enzyme-linked immunosorbent assay (ELISA). However, infection can spontaneously clear from the mucosa during the progression of atrophy and could lead to substantial under-detection of infection and underestimation of its effect on gastric cancer (GC) risk. Antibodies detected by western blot are known to persist longer after the loss of the infection. In a nested case-control study from the Eurogast-EPIC cohort, including 88 noncardia GC cases and 338 controls, we assessed the association between noncardia GC and H. pylori infection comparing antibodies detected by western blot (HELICOBLOT2.1) to those detected by ELISA (Pyloriset EIA-GIII((R))). By immunoblot, 82 cases (93.2%) were H. pylori positive, 10 of these cases (11.4%) were negative by ELISA and only 6 cases (6.8%) were negative by both ELISA and immunoblot. Multivariable odds ratio (OR) for noncardia GC comparing immunoglobulin G positive versus negative by ELISA was 6.8 [95% confidence interval (CI) 3.0-15.1], and by immunoblot, the OR was 21.4 (95% CI 7.1-64.4). Using a western blot assay, nearly all noncardia GC were classified as H. pylori positive and the OR was more than threefold higher than the OR assessed by ELISA, supporting the hypothesis that H. pylori infection is a necessary condition for noncardia GC. | |
650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Cancer och onkologi0 (SwePub)302032 hsv//swe |
650 | 7 | a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Cancer and Oncology0 (SwePub)302032 hsv//eng |
653 | a Helicobacter pylori | |
653 | a noncardia gastric cancer | |
653 | a prospective study | |
653 | a western blot | |
653 | a Helicobacter pylori | |
700 | 1 | a Megraud, F.4 aut |
700 | 1 | a Buissonniere, A.4 aut |
700 | 1 | a Lujan Barroso, L.4 aut |
700 | 1 | a Agudo, A.4 aut |
700 | 1 | a Duell, E. J.4 aut |
700 | 1 | a Boutron-Ruault, M. C.4 aut |
700 | 1 | a Clavel-Chapelon, F.4 aut |
700 | 1 | a Palli, D.4 aut |
700 | 1 | a Krogh, V.4 aut |
700 | 1 | a Mattiello, A.4 aut |
700 | 1 | a Tumino, R.4 aut |
700 | 1 | a Sacerdote, C.4 aut |
700 | 1 | a Quiros, J. R.4 aut |
700 | 1 | a Sanchez-Cantalejo, E.4 aut |
700 | 1 | a Navarro, C.4 aut |
700 | 1 | a Barricarte, A.4 aut |
700 | 1 | a Dorronsoro, M.4 aut |
700 | 1 | a Khaw, K. -T.4 aut |
700 | 1 | a Wareham, N.4 aut |
700 | 1 | a Allen, N. E.4 aut |
700 | 1 | a Tsilidis, K. K.4 aut |
700 | 1 | a Bueno-de-Mesquita, H. Bas4 aut |
700 | 1 | a Jeurnink, S. M.4 aut |
700 | 1 | a Numans, M. E.4 aut |
700 | 1 | a Peeters, P. H. M.4 aut |
700 | 1 | a Lagiou, P.4 aut |
700 | 1 | a Valanou, E.4 aut |
700 | 1 | a Trichopoulou, A.4 aut |
700 | 1 | a Kaaks, R.4 aut |
700 | 1 | a Lukanova-McGregor, A.4 aut |
700 | 1 | a Bergman, M. M.4 aut |
700 | 1 | a Boeing, H.4 aut |
700 | 1 | a Manjer, Jonasu Lund University,Lunds universitet,Kirurgi,Forskargrupper vid Lunds universitet,Surgery,Lund University Research Groups4 aut0 (Swepub:lu)smi-jma |
700 | 1 | a Lindkvist, B.4 aut |
700 | 1 | a Stenling, Rogeru Umeå universitet,Institutionen för medicinsk biovetenskap4 aut0 (Swepub:umu)rost0001 |
700 | 1 | a Hallmans, Göranu Umeå universitet,Näringsforskning4 aut0 (Swepub:umu)goha0001 |
700 | 1 | a Mortensen, L. M.4 aut |
700 | 1 | a Overvad, K.4 aut |
700 | 1 | a Olsen, A.4 aut |
700 | 1 | a Tjonneland, A.4 aut |
700 | 1 | a Bakken, K.4 aut |
700 | 1 | a Dumeaux, V.4 aut |
700 | 1 | a Lund, E.4 aut |
700 | 1 | a Jenab, M.4 aut |
700 | 1 | a Romieu, I.4 aut |
700 | 1 | a Michaud, D.4 aut |
700 | 1 | a Mouw, T.4 aut |
700 | 1 | a Carneiro, F.4 aut |
700 | 1 | a Fenge, C.4 aut |
700 | 1 | a Riboli, E.4 aut |
710 | 2 | a Kirurgib Forskargrupper vid Lunds universitet4 org |
773 | 0 | t Annals of Oncologyd : Elsevier BVg 23:5, s. 1320-1324q 23:5<1320-1324x 1569-8041x 0923-7534 |
856 | 4 | u http://dx.doi.org/10.1093/annonc/mdr384y FULLTEXT |
856 | 4 | u https://doi.org/10.1093/annonc/mdr384 |
856 | 4 8 | u https://lup.lub.lu.se/record/2551569 |
856 | 4 8 | u https://doi.org/10.1093/annonc/mdr384 |
856 | 4 8 | u https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-55667 |
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