Sökning: WFRF:(Belousova E.) > East-West gradient ...
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000 | 13130naa a2201045 4500 | |
001 | oai:DiVA.org:liu-107459 | |
003 | SwePub | |
008 | 140612s2014 | |||||||||||000 ||eng| | |
009 | oai:DiVA.org:oru-36004 | |
009 | oai:prod.swepub.kib.ki.se:128984961 | |
024 | 7 | a https://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-1074592 URI |
024 | 7 | a https://doi.org/10.1136/gutjnl-2013-3046362 DOI |
024 | 7 | a https://urn.kb.se/resolve?urn=urn:nbn:se:oru:diva-360042 URI |
024 | 7 | a http://kipublications.ki.se/Default.aspx?queryparsed=id:1289849612 URI |
040 | a (SwePub)liud (SwePub)orud (SwePub)ki | |
041 | a engb eng | |
042 | 9 SwePub | |
072 | 7 | a ref2 swepub-contenttype |
072 | 7 | a art2 swepub-publicationtype |
100 | 1 | a Burisch, J.u Digestive Disease Centre, Medical Section, Herlev University Hospital, Copenhagen, Denmark4 aut |
245 | 1 0 | a East-West gradient in the incidence of inflammatory bowel disease in Europe: the ECCO-EpiCom inception cohort |
264 | c 2013-04-20 | |
264 | 1 | b BMJ Publishing Group,c 2014 |
338 | a print2 rdacarrier | |
520 | a Objective The incidence of inflammatory bowel disease (IBD) is increasing in Eastern Europe. The reasons for these changes remain unknown. The aim of this study was to investigate whether an East–West gradient in the incidence of IBD in Europe exists.Design A prospective, uniformly diagnosed, population based inception cohort of IBD patients in 31 centres from 14 Western and eight Eastern European countries covering a total background population of approximately 10.1 million people was created. One-third of the centres had previous experience with inception cohorts. Patients were entered into a low cost, web based epidemiological database, making participation possible regardless of socioeconomic status and prior experience.Results 1515 patients aged 15 years or older were included, of whom 535 (35%) were diagnosed with Crohn's disease (CD), 813 (54%) with ulcerative colitis (UC) and 167 (11%) with IBD unclassified (IBDU). The overall incidence rate ratios in all Western European centres were 1.9 (95% CI 1.5 to 2.4) for CD and 2.1 (95% CI 1.8 to 2.6) for UC compared with Eastern European centres. The median crude annual incidence rates per 100 000 in 2010 for CD were 6.5 (range 0–10.7) in Western European centres and 3.1 (range 0.4–11.5) in Eastern European centres, for UC 10.8 (range 2.9–31.5) and 4.1 (range 2.4–10.3), respectively, and for IBDU 1.9 (range 0–39.4) and 0 (range 0–1.2), respectively. In Western Europe, 92% of CD, 78% of UC and 74% of IBDU patients had a colonoscopy performed as the diagnostic procedure compared with 90%, 100% and 96%, respectively, in Eastern Europe. 8% of CD and 1% of UC patients in both regions underwent surgery within the first 3 months of the onset of disease. 7% of CD patients and 3% of UC patients from Western Europe received biological treatment as rescue therapy. Of all European CD patients, 20% received only 5-aminosalicylates as induction therapy.Conclusions An East–West gradient in IBD incidence exists in Europe. Among this inception cohort—including indolent and aggressive cases—international guidelines for diagnosis and initial treatment are not being followed uniformly by physicians. | |
650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Gastroenterologi0 (SwePub)302132 hsv//swe |
650 | 7 | a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Gastroenterology and Hepatology0 (SwePub)302132 hsv//eng |
653 | a MEDICINE | |
653 | a MEDICIN | |
653 | a Invärtesmedicin | |
700 | 1 | a Pedersen, N.u Digestive Disease Centre, Medical Section, Herlev University Hospital, Copenhagen, Denmark4 aut |
700 | 1 | a Cukovic-Cavka, S.u Division of Gastroenterology and Hepatology, University Hospital Centre Zagreb, University of Zagreb School of Medicine, Zagreb, Croatia,Hull and East Yorkshire NHS Trust and Hull and York Medical School, Hull Royal Infirmary, Hull, UK,Hull and E Yorkshire NHS Trust and Hull and York, England4 aut |
700 | 1 | a Brinar, M.u Division of Gastroenterology and Hepatology, University Hospital Centre Zagreb, University of Zagreb School of Medicine, Zagreb, Croatia4 aut |
700 | 1 | a Kaimakliotis, I.u Nicosia private practice, Nicosia, Cyprus4 aut |
700 | 1 | a Duricova, D.u Charles University of Prague, Czech Republic,IBD Centre ISCARE, Charles University, Prague, Czech Republic,Department of Gastroenterology and Hepatology, Soroka Medical Centre and Ben Gurion University of the Negev, Beer Sheva, Israel,UO Gastroenterologia, Azienda Ospedaliera-Università di Padova, Padova, Italy,Clinic of Gastroenterology, University of Medicine ‘Victor Babes’, Timisoara, Romania,Gastroenterology Department, Complexo Hospitalario Universitario de Vigo, Vigo, Spain,University of Medical Victor Babes, Romania,Complexo Hospital University of Vigo, Spain4 aut |
700 | 1 | a Shonova, O.u Gastroenterology Department, Hospital České Budějovice, České Budějovice, Czech Republic,Department of Gastroenterology and Hepatology, Soroka Medical Centre and Ben Gurion University of the Negev, Beer Sheva, Israel4 aut |
700 | 1 | a Vind, I.u Department of Medicine, Amager Hospital, Amager, Denmark4 aut |
700 | 1 | a Avnstrom, S.u Department of Medicine, Amager Hospital, Amager, Denmark4 aut |
700 | 1 | a Thorsgaard, N.u Department of Medicine, Herning Central Hospital, Herning, Denmark4 aut |
700 | 1 | a Andersen, V.u Medical Department, Viborg Regional Hospital, Viborg, Denmark; Medical Department, Hospital of Southern Jutland, Aabenraa, Denmark; University of Southern Denmark, Odense, Denmark4 aut |
700 | 1 | a Krabbe, S.u Medical Department, Viborg Regional Hospital, Viborg, Denmark4 aut |
700 | 1 | a Dahlerup, J.F.u Department of Medicine V (Hepatology and Gastroenterology), Aarhus University Hospital, Arhus, Denmark4 aut |
700 | 1 | a Salupere, R.u Division of Endocrinology and Gastroenterology, Tartu University Hospital, Tartu, Estonia4 aut |
700 | 1 | a Nielsen, K.R.u National Hospital Faroe Isl, Denmark,Medical Department, The National Hospital of the Faroe Islands, Torshavn, Faroe Islands4 aut |
700 | 1 | a Olsen, J.u National Hospital Faroe Isl, Denmark,Medical Department, The National Hospital of the Faroe Islands, Torshavn, Faroe Islands4 aut |
700 | 1 | a Manninen, P.u Department of Gastroenterology and Alimentary Tract Surgery, Tampere University Hospital, Tampere, Finland4 aut |
700 | 1 | a Collin, P.u Department of Gastroenterology and Alimentary Tract Surgery, Tampere University Hospital, Tampere, Finland4 aut |
700 | 1 | a Tsianos, E.V.u 1st Division of Internal Medicine and Hepato-Gastroenterology Unit, University Hospital, Ioannina, Greece4 aut |
700 | 1 | a Katsanos, K.H.u 1st Division of Internal Medicine and Hepato-Gastroenterology Unit, University Hospital, Ioannina, Greece4 aut |
700 | 1 | a Ladefoged, K.u Medical Department, Dronning Ingrids Hospital, Nuuk, Greenland,Institute for Digestive Research, Lithuanian University of Health Sciences, Kaunas, Lithuania,Az Osped Osped Cremona, Italy Lithuanian University of Health Science, Lithuania4 aut |
700 | 1 | a Lakatos, L.u 1st Department of Medicine, Semmelweis University, Budapest, Hungary,Hospital de Vale de Sousa, Porto, Portugal4 aut |
700 | 1 | a Bjornsson, E.u Department of Internal Medicine, Section of Gastroenterology and Hepatology, The National University Hospital, Reykjavik, Iceland4 aut |
700 | 1 | a Ragnarsson, G.u Department of Internal Medicine, Section of Gastroenterology and Hepatology, The National University Hospital, Reykjavik, Iceland4 aut |
700 | 1 | a Bailey, Y.u Department of Gastroenterology, Adelaide and Meath Hospital, TCD, Dublin, Ireland4 aut |
700 | 1 | a Odes, S.u Ben Gurion University of Negev, Israel Ben Gurion University of Negev, Israel4 aut |
700 | 1 | a Schwartz, D.u Ben Gurion University of Negev, Israel Ben Gurion University of Negev, Israel4 aut |
700 | 1 | a Martinato, M.u UO Gastroenterologia, Azienda Ospedaliera—Università di Padova, Padova, Italy,Gastroenterology Unit, Careggi Hospital, Florence, Italy,UO Gastroenterologia ed Endoscopia Digestiva, Ospedale Morgagni-Pierantoni, Forlì, Italy,Azienda Osped Arcispedale S Maria Nuova, Italy4 aut |
700 | 1 | a Lupinacci, G.u UO Gastroenterol Endoscopia Digest, Italy,UO di Medicina e Gastroenterologia, Az Ospedaliera Ospedale di Cremona, Cremona, Italy; UO di Gastroenterologia e Endoscopia Digestiva, Az Ospedaliera Ospedale Maggiore di Crema, Crema, Italy4 aut |
700 | 1 | a Milla, M.u Careggi Hospital, Italy4 aut |
700 | 1 | a De Padova, A.u Osped Morgagni Pierantoni, Italy,UO Gastroenterologia ed Endoscopia Digestiva, Ospedale Morgagni-Pierantoni, Forlì, Italy4 aut |
700 | 1 | a D'lnca, R.u Azienda Ospedaliera—Università di Padova, Padova, Italy4 aut |
700 | 1 | a Beltrami, M.u Azienda Osped Arcispedale S Maria Nuova, Italy4 aut |
700 | 1 | a Kupcinskas, L.u Az Osped Osped Cremona, Italy Lithuanian University of Health Science, Lithuania4 aut |
700 | 1 | a Kiudelis, G.u Institute for Digestive Research, Lithuanian University of Health Sciences, Kaunas, Lithuania4 aut |
700 | 1 | a Turcan, S.u Department of Gastroenterology, State University of Medicine and Pharmacy of the Republic of Moldova, Chisinau, Republic of Moldova4 aut |
700 | 1 | a Tighineanu, O.u Department of Paediatric Gastroenterology, Centre of Mother and Child, Chisinau, Republic of Moldova4 aut |
700 | 1 | a Mihu, I.u Department of Paediatric Gastroenterology, Centre of Mother and Child, Chisinau, Republic of Moldova4 aut |
700 | 1 | a Magro, F.u Hospital Sao Joao, Portugal Oporto Medical Sch, Portugal University of Porto, Portugal,Department of Gastroenterology, Hospital de São João, Porto, Portugal; Institute of Pharmacology and Therapeutics, Oporto Medical School, Porto, Portugal; Hospital de Vale de Sousa, Porto, Portugal4 aut |
700 | 1 | a Barros, L.F.u Hospital Vale Sousa, Portugal4 aut |
700 | 1 | a Goldis, A.u University of Medical Victor Babes, Romania,Clinic of Gastroenterology, University of Medicine ‘Victor Babes’, Timisoara, Romania4 aut |
700 | 1 | a Lazar, D.u University of Medical Victor Babes, Romania4 aut |
700 | 1 | a Belousova, E.u Moscow Regional Research Clin Institute, Russia,Department of Gastroenterology, Moscow Regional Research Clinical Institute, Moscow, Russia4 aut |
700 | 1 | a Nikulina, I.u Moscow Regional Research Clin Institute, Russia,Department of Gastroenterology, Moscow Regional Research Clinical Institute, Moscow, Russia4 aut |
700 | 1 | a Hernandez, V.u Complexo Hospital University of Vigo, Spain,Gastroenterology Department, Complexo Hospitalario Universitario de Vigo, Vigo, Spain4 aut |
700 | 1 | a Martinez-Ares, D.u Complexo Hospital University of Vigo, Spain4 aut |
700 | 1 | a Almer, Svenu Karolinska Institutet,Östergötlands Läns Landsting,Linköpings universitet,Avdelningen för inflammationsmedicin,Hälsouniversitetet,Magtarmmedicinska kliniken,Division of Gastroenterology and Hepatology, Department of Clinical and Experimental Medicine, Linköping University, Linköping, Sweden; Department of Gastroenterology/UHL, County Council of Östergötland, Linköping, Sweden4 aut0 (Swepub:liu)sveal38 |
700 | 1 | a Zhulina, Yaroslava,d 1973-u Region Örebro län,Department of Medicine, Division of Gastroenterology, Örebro University Hospital, Örebro, Sweden4 aut0 (Swepub:oru)yza |
700 | 1 | a Halfvarson, Jonas,d 1970-u Region Örebro län,Örebro universitet, Institutionen för hälsovetenskap och medicin,Department of Medicine, Division of Gastroenterology, Örebro University Hospital, Örebro, Sweden4 aut0 (Swepub:oru)jshn |
700 | 1 | a Arebi, N.u University of London Imperial Coll Science Technology and Med, England,Sir Alan Park's Physiology Unit, St Mark's Hospital, Imperial College London, London, UK4 aut |
700 | 1 | a Sebastian, S.u Hull and E Yorkshire NHS Trust and Hull and York, England4 aut |
700 | 1 | a Lakatos, P.L.u Semmelweis University, Budapest, Hungary4 aut |
700 | 1 | a Langholz, E.u Gentofte University Hospital, Denmark,Department of Medical Gastroenterology, Gentofte Hospital, Copenhagen, Denmark4 aut |
700 | 1 | a Munkholm, P.u Digestive Disease Centre, Medical Section, Herlev University Hospital, Copenhagen, Denmark4 aut |
710 | 2 | a Digestive Disease Centre, Medical Section, Herlev University Hospital, Copenhagen, Denmarkb Division of Gastroenterology and Hepatology, University Hospital Centre Zagreb, University of Zagreb School of Medicine, Zagreb, Croatia4 org |
773 | 0 | t Gutd : BMJ Publishing Groupg 63:4, s. 588-597q 63:4<588-597x 0017-5749x 1468-3288 |
856 | 4 | u https://www.hirsla.lsh.is/bitstream/2336/325171/1/Gut-2014-Burisch-588-97.pdf |
856 | 4 8 | u https://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-107459 |
856 | 4 8 | u https://doi.org/10.1136/gutjnl-2013-304636 |
856 | 4 8 | u https://urn.kb.se/resolve?urn=urn:nbn:se:oru:diva-36004 |
856 | 4 8 | u http://kipublications.ki.se/Default.aspx?queryparsed=id:128984961 |
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