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FältnamnIndikatorerMetadata
00013130naa a2201045 4500
001oai:DiVA.org:liu-107459
003SwePub
008140612s2014 | |||||||||||000 ||eng|
009oai:DiVA.org:oru-36004
009oai:prod.swepub.kib.ki.se:128984961
024a https://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-1074592 URI
024a https://doi.org/10.1136/gutjnl-2013-3046362 DOI
024a https://urn.kb.se/resolve?urn=urn:nbn:se:oru:diva-360042 URI
024a http://kipublications.ki.se/Default.aspx?queryparsed=id:1289849612 URI
040 a (SwePub)liud (SwePub)orud (SwePub)ki
041 a engb eng
042 9 SwePub
072 7a ref2 swepub-contenttype
072 7a art2 swepub-publicationtype
100a Burisch, J.u Digestive Disease Centre, Medical Section, Herlev University Hospital, Copenhagen, Denmark4 aut
2451 0a East-West gradient in the incidence of inflammatory bowel disease in Europe: the ECCO-EpiCom inception cohort
264 c 2013-04-20
264 1b BMJ Publishing Group,c 2014
338 a print2 rdacarrier
520 a Objective The incidence of inflammatory bowel disease (IBD) is increasing in Eastern Europe. The reasons for these changes remain unknown. The aim of this study was to investigate whether an East–West gradient in the incidence of IBD in Europe exists.Design A prospective, uniformly diagnosed, population based inception cohort of IBD patients in 31 centres from 14 Western and eight Eastern European countries covering a total background population of approximately 10.1 million people was created. One-third of the centres had previous experience with inception cohorts. Patients were entered into a low cost, web based epidemiological database, making participation possible regardless of socioeconomic status and prior experience.Results 1515 patients aged 15 years or older were included, of whom 535 (35%) were diagnosed with Crohn's disease (CD), 813 (54%) with ulcerative colitis (UC) and 167 (11%) with IBD unclassified (IBDU). The overall incidence rate ratios in all Western European centres were 1.9 (95% CI 1.5 to 2.4) for CD and 2.1 (95% CI 1.8 to 2.6) for UC compared with Eastern European centres. The median crude annual incidence rates per 100 000 in 2010 for CD were 6.5 (range 0–10.7) in Western European centres and 3.1 (range 0.4–11.5) in Eastern European centres, for UC 10.8 (range 2.9–31.5) and 4.1 (range 2.4–10.3), respectively, and for IBDU 1.9 (range 0–39.4) and 0 (range 0–1.2), respectively. In Western Europe, 92% of CD, 78% of UC and 74% of IBDU patients had a colonoscopy performed as the diagnostic procedure compared with 90%, 100% and 96%, respectively, in Eastern Europe. 8% of CD and 1% of UC patients in both regions underwent surgery within the first 3 months of the onset of disease. 7% of CD patients and 3% of UC patients from Western Europe received biological treatment as rescue therapy. Of all European CD patients, 20% received only 5-aminosalicylates as induction therapy.Conclusions An East–West gradient in IBD incidence exists in Europe. Among this inception cohort—including indolent and aggressive cases—international guidelines for diagnosis and initial treatment are not being followed uniformly by physicians.
650 7a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Gastroenterologi0 (SwePub)302132 hsv//swe
650 7a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Gastroenterology and Hepatology0 (SwePub)302132 hsv//eng
653 a MEDICINE
653 a MEDICIN
653 a Invärtesmedicin
700a Pedersen, N.u Digestive Disease Centre, Medical Section, Herlev University Hospital, Copenhagen, Denmark4 aut
700a Cukovic-Cavka, S.u Division of Gastroenterology and Hepatology, University Hospital Centre Zagreb, University of Zagreb School of Medicine, Zagreb, Croatia,Hull and East Yorkshire NHS Trust and Hull and York Medical School, Hull Royal Infirmary, Hull, UK,Hull and E Yorkshire NHS Trust and Hull and York, England4 aut
700a Brinar, M.u Division of Gastroenterology and Hepatology, University Hospital Centre Zagreb, University of Zagreb School of Medicine, Zagreb, Croatia4 aut
700a Kaimakliotis, I.u Nicosia private practice, Nicosia, Cyprus4 aut
700a Duricova, D.u Charles University of Prague, Czech Republic,IBD Centre ISCARE, Charles University, Prague, Czech Republic,Department of Gastroenterology and Hepatology, Soroka Medical Centre and Ben Gurion University of the Negev, Beer Sheva, Israel,UO Gastroenterologia, Azienda Ospedaliera-Università di Padova, Padova, Italy,Clinic of Gastroenterology, University of Medicine ‘Victor Babes’, Timisoara, Romania,Gastroenterology Department, Complexo Hospitalario Universitario de Vigo, Vigo, Spain,University of Medical Victor Babes, Romania,Complexo Hospital University of Vigo, Spain4 aut
700a Shonova, O.u Gastroenterology Department, Hospital České Budějovice, České Budějovice, Czech Republic,Department of Gastroenterology and Hepatology, Soroka Medical Centre and Ben Gurion University of the Negev, Beer Sheva, Israel4 aut
700a Vind, I.u Department of Medicine, Amager Hospital, Amager, Denmark4 aut
700a Avnstrom, S.u Department of Medicine, Amager Hospital, Amager, Denmark4 aut
700a Thorsgaard, N.u Department of Medicine, Herning Central Hospital, Herning, Denmark4 aut
700a Andersen, V.u Medical Department, Viborg Regional Hospital, Viborg, Denmark; Medical Department, Hospital of Southern Jutland, Aabenraa, Denmark; University of Southern Denmark, Odense, Denmark4 aut
700a Krabbe, S.u Medical Department, Viborg Regional Hospital, Viborg, Denmark4 aut
700a Dahlerup, J.F.u Department of Medicine V (Hepatology and Gastroenterology), Aarhus University Hospital, Arhus, Denmark4 aut
700a Salupere, R.u Division of Endocrinology and Gastroenterology, Tartu University Hospital, Tartu, Estonia4 aut
700a Nielsen, K.R.u National Hospital Faroe Isl, Denmark,Medical Department, The National Hospital of the Faroe Islands, Torshavn, Faroe Islands4 aut
700a Olsen, J.u National Hospital Faroe Isl, Denmark,Medical Department, The National Hospital of the Faroe Islands, Torshavn, Faroe Islands4 aut
700a Manninen, P.u Department of Gastroenterology and Alimentary Tract Surgery, Tampere University Hospital, Tampere, Finland4 aut
700a Collin, P.u Department of Gastroenterology and Alimentary Tract Surgery, Tampere University Hospital, Tampere, Finland4 aut
700a Tsianos, E.V.u 1st Division of Internal Medicine and Hepato-Gastroenterology Unit, University Hospital, Ioannina, Greece4 aut
700a Katsanos, K.H.u 1st Division of Internal Medicine and Hepato-Gastroenterology Unit, University Hospital, Ioannina, Greece4 aut
700a Ladefoged, K.u Medical Department, Dronning Ingrids Hospital, Nuuk, Greenland,Institute for Digestive Research, Lithuanian University of Health Sciences, Kaunas, Lithuania,Az Osped Osped Cremona, Italy Lithuanian University of Health Science, Lithuania4 aut
700a Lakatos, L.u 1st Department of Medicine, Semmelweis University, Budapest, Hungary,Hospital de Vale de Sousa, Porto, Portugal4 aut
700a Bjornsson, E.u Department of Internal Medicine, Section of Gastroenterology and Hepatology, The National University Hospital, Reykjavik, Iceland4 aut
700a Ragnarsson, G.u Department of Internal Medicine, Section of Gastroenterology and Hepatology, The National University Hospital, Reykjavik, Iceland4 aut
700a Bailey, Y.u Department of Gastroenterology, Adelaide and Meath Hospital, TCD, Dublin, Ireland4 aut
700a Odes, S.u Ben Gurion University of Negev, Israel Ben Gurion University of Negev, Israel4 aut
700a Schwartz, D.u Ben Gurion University of Negev, Israel Ben Gurion University of Negev, Israel4 aut
700a Martinato, M.u UO Gastroenterologia, Azienda Ospedaliera—Università di Padova, Padova, Italy,Gastroenterology Unit, Careggi Hospital, Florence, Italy,UO Gastroenterologia ed Endoscopia Digestiva, Ospedale Morgagni-Pierantoni, Forlì, Italy,Azienda Osped Arcispedale S Maria Nuova, Italy4 aut
700a Lupinacci, G.u UO Gastroenterol Endoscopia Digest, Italy,UO di Medicina e Gastroenterologia, Az Ospedaliera Ospedale di Cremona, Cremona, Italy; UO di Gastroenterologia e Endoscopia Digestiva, Az Ospedaliera Ospedale Maggiore di Crema, Crema, Italy4 aut
700a Milla, M.u Careggi Hospital, Italy4 aut
700a De Padova, A.u Osped Morgagni Pierantoni, Italy,UO Gastroenterologia ed Endoscopia Digestiva, Ospedale Morgagni-Pierantoni, Forlì, Italy4 aut
700a D'lnca, R.u Azienda Ospedaliera—Università di Padova, Padova, Italy4 aut
700a Beltrami, M.u Azienda Osped Arcispedale S Maria Nuova, Italy4 aut
700a Kupcinskas, L.u Az Osped Osped Cremona, Italy Lithuanian University of Health Science, Lithuania4 aut
700a Kiudelis, G.u Institute for Digestive Research, Lithuanian University of Health Sciences, Kaunas, Lithuania4 aut
700a Turcan, S.u Department of Gastroenterology, State University of Medicine and Pharmacy of the Republic of Moldova, Chisinau, Republic of Moldova4 aut
700a Tighineanu, O.u Department of Paediatric Gastroenterology, Centre of Mother and Child, Chisinau, Republic of Moldova4 aut
700a Mihu, I.u Department of Paediatric Gastroenterology, Centre of Mother and Child, Chisinau, Republic of Moldova4 aut
700a Magro, F.u Hospital Sao Joao, Portugal Oporto Medical Sch, Portugal University of Porto, Portugal,Department of Gastroenterology, Hospital de São João, Porto, Portugal; Institute of Pharmacology and Therapeutics, Oporto Medical School, Porto, Portugal; Hospital de Vale de Sousa, Porto, Portugal4 aut
700a Barros, L.F.u Hospital Vale Sousa, Portugal4 aut
700a Goldis, A.u University of Medical Victor Babes, Romania,Clinic of Gastroenterology, University of Medicine ‘Victor Babes’, Timisoara, Romania4 aut
700a Lazar, D.u University of Medical Victor Babes, Romania4 aut
700a Belousova, E.u Moscow Regional Research Clin Institute, Russia,Department of Gastroenterology, Moscow Regional Research Clinical Institute, Moscow, Russia4 aut
700a Nikulina, I.u Moscow Regional Research Clin Institute, Russia,Department of Gastroenterology, Moscow Regional Research Clinical Institute, Moscow, Russia4 aut
700a Hernandez, V.u Complexo Hospital University of Vigo, Spain,Gastroenterology Department, Complexo Hospitalario Universitario de Vigo, Vigo, Spain4 aut
700a Martinez-Ares, D.u Complexo Hospital University of Vigo, Spain4 aut
700a Almer, Svenu Karolinska Institutet,Östergötlands Läns Landsting,Linköpings universitet,Avdelningen för inflammationsmedicin,Hälsouniversitetet,Magtarmmedicinska kliniken,Division of Gastroenterology and Hepatology, Department of Clinical and Experimental Medicine, Linköping University, Linköping, Sweden; Department of Gastroenterology/UHL, County Council of Östergötland, Linköping, Sweden4 aut0 (Swepub:liu)sveal38
700a Zhulina, Yaroslava,d 1973-u Region Örebro län,Department of Medicine, Division of Gastroenterology, Örebro University Hospital, Örebro, Sweden4 aut0 (Swepub:oru)yza
700a Halfvarson, Jonas,d 1970-u Region Örebro län,Örebro universitet, Institutionen för hälsovetenskap och medicin,Department of Medicine, Division of Gastroenterology, Örebro University Hospital, Örebro, Sweden4 aut0 (Swepub:oru)jshn
700a Arebi, N.u University of London Imperial Coll Science Technology and Med, England,Sir Alan Park's Physiology Unit, St Mark's Hospital, Imperial College London, London, UK4 aut
700a Sebastian, S.u Hull and E Yorkshire NHS Trust and Hull and York, England4 aut
700a Lakatos, P.L.u Semmelweis University, Budapest, Hungary4 aut
700a Langholz, E.u Gentofte University Hospital, Denmark,Department of Medical Gastroenterology, Gentofte Hospital, Copenhagen, Denmark4 aut
700a Munkholm, P.u Digestive Disease Centre, Medical Section, Herlev University Hospital, Copenhagen, Denmark4 aut
710a Digestive Disease Centre, Medical Section, Herlev University Hospital, Copenhagen, Denmarkb Division of Gastroenterology and Hepatology, University Hospital Centre Zagreb, University of Zagreb School of Medicine, Zagreb, Croatia4 org
773t Gutd : BMJ Publishing Groupg 63:4, s. 588-597q 63:4<588-597x 0017-5749x 1468-3288
856u https://www.hirsla.lsh.is/bitstream/2336/325171/1/Gut-2014-Burisch-588-97.pdf
8564 8u https://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-107459
8564 8u https://doi.org/10.1136/gutjnl-2013-304636
8564 8u https://urn.kb.se/resolve?urn=urn:nbn:se:oru:diva-36004
8564 8u http://kipublications.ki.se/Default.aspx?queryparsed=id:128984961

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