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Postural orthostatic tachycardia syndrome (POTS) : State of the science and clinical care from a 2019 National Institutes of Health Expert Consensus Meeting - Part 1

Vernino, Steven (författare)
University of Texas Southwestern Medical Center
Bourne, Kate M. (författare)
University of Calgary
Stiles, Lauren E. (författare)
Dysautonomia International,Stony Brook University
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Grubb, Blair P. (författare)
The University of Toledo Medical Center
Fedorowski, Artur (författare)
Lund University,Lunds universitet,Kardiovaskulär forskning - hypertoni,Forskargrupper vid Lunds universitet,Cardiovascular Research - Hypertension,Lund University Research Groups,Skåne University Hospital
Stewart, Julian M. (författare)
New York Medical College
Arnold, Amy C. (författare)
Vanderbilt University,Pennsylvania State University
Pace, Laura A. (författare)
University of Utah
Axelsson, Jonas (författare)
Karolinska University Hospital
Boris, Jeffrey R. (författare)
Jeffrey R Boris MD LLC
Moak, Jeffrey P. (författare)
George Washington University
Goodman, Brent P. (författare)
Mayo Clinic Scottsdale-Phoenix, Arizona
Chémali, Kamal R. (författare)
Sentara Healthcare
Chung, Tae H. (författare)
Johns Hopkins University School of Medicine
Goldstein, David S. (författare)
National Institutes of Health, United States
Diedrich, Andre (författare)
Vanderbilt University
Miglis, Mitchell G. (författare)
Stanford University
Cortez, Melissa M. (författare)
University of Utah
Miller, Amanda J. (författare)
Pennsylvania State University
Freeman, Roy (författare)
Beth Israel Deaconess Medical Center,Harvard Medical School
Biaggioni, Italo (författare)
Vanderbilt University
Rowe, Peter C. (författare)
Johns Hopkins University
Sheldon, Robert S. (författare)
University of Calgary
Shibao, Cyndya A. (författare)
Vanderbilt University
Systrom, David M. (författare)
Harvard Medical School
Cook, Glen A. (författare)
Uniformed Services University of the Health Sciences
Doherty, Taylor A. (författare)
University of California, San Diego
Abdallah, Hasan I. (författare)
Children's Heart Institute
Darbari, Anil (författare)
George Washington University
Raj, Satish R. (författare)
University of Calgary
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 (creator_code:org_t)
Elsevier BV, 2021
2021
Engelska.
Ingår i: Autonomic Neuroscience: Basic and Clinical. - : Elsevier BV. - 1566-0702. ; 235
Relaterad länk:
http://dx.doi.org/10... (free)
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http://www.autonomic...
https://lup.lub.lu.s...
https://doi.org/10.1...
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  • Tidskriftsartikel (refereegranskat)
Abstract Ämnesord
Stäng  
  • Postural orthostatic tachycardia syndrome (POTS) is a chronic and often disabling disorder characterized by orthostatic intolerance with excessive heart rate increase without hypotension during upright posture. Patients often experience a constellation of other typical symptoms including fatigue, exercise intolerance and gastrointestinal distress. A typical patient with POTS is a female of child-bearing age, who often first displays symptoms in adolescence. The onset of POTS may be precipitated by immunological stressors such as a viral infection. A variety of pathophysiologies are involved in the abnormal postural tachycardia response; however, the pathophysiology of the syndrome is incompletely understood and undoubtedly multifaceted. Clinicians and researchers focused on POTS convened at the National Institutes of Health in July 2019 to discuss the current state of understanding of the pathophysiology of POTS and to identify priorities for POTS research. This article, the first of two articles summarizing the information discussed at this meeting, summarizes the current understanding of this disorder and best practices for clinical care. The evaluation of a patient with suspected POTS should seek to establish the diagnosis, identify co-morbid conditions, and exclude conditions that could cause or mimic the syndrome. Once diagnosed, management typically begins with patient education and non-pharmacologic treatment options. Various medications are often used to address specific symptoms, but there are currently no FDA-approved medications for the treatment of POTS, and evidence for many of the medications used to treat POTS is not robust.

Ämnesord

MEDICIN OCH HÄLSOVETENSKAP  -- Klinisk medicin -- Kardiologi (hsv//swe)
MEDICAL AND HEALTH SCIENCES  -- Clinical Medicine -- Cardiac and Cardiovascular Systems (hsv//eng)

Nyckelord

Expert consensus
Pathophysiology
Postural orthostatic tachycardia syndrome
Treatment
Workshop

Publikations- och innehållstyp

art (ämneskategori)
ref (ämneskategori)

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