WFRF:(Liu XN)
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| Fältnamn | Indikatorer | Metadata |
|---|---|---|
| 000 | 03834naa a2200973 4500 | |
| 001 | oai:prod.swepub.kib.ki.se:148325402 | |
| 003 | SwePub | |
| 008 | 240701s2021 | |||||||||||000 ||eng| | |
| 024 | 7 | a http://kipublications.ki.se/Default.aspx?queryparsed=id:1483254022 URI |
| 024 | 7 | a https://doi.org/10.1038/s41467-021-27162-22 DOI |
| 040 | a (SwePub)ki | |
| 041 | a engb eng | |
| 042 | 9 SwePub | |
| 072 | 7 | a ref2 swepub-contenttype |
| 072 | 7 | a art2 swepub-publicationtype |
| 100 | 1 | a Chen, DS4 aut |
| 245 | 1 0 | a Single cell atlas for 11 non-model mammals, reptiles and birds |
| 264 | c 2021-12-06 | |
| 264 | 1 | b Springer Science and Business Media LLC,c 2021 |
| 520 | a The availability of viral entry factors is a prerequisite for the cross-species transmission of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Large-scale single-cell screening of animal cells could reveal the expression patterns of viral entry genes in different hosts. However, such exploration for SARS-CoV-2 remains limited. Here, we perform single-nucleus RNA sequencing for 11 non-model species, including pets (cat, dog, hamster, and lizard), livestock (goat and rabbit), poultry (duck and pigeon), and wildlife (pangolin, tiger, and deer), and investigated the co-expression of ACE2 and TMPRSS2. Furthermore, cross-species analysis of the lung cell atlas of the studied mammals, reptiles, and birds reveals core developmental programs, critical connectomes, and conserved regulatory circuits among these evolutionarily distant species. Overall, our work provides a compendium of gene expression profiles for non-model animals, which could be employed to identify potential SARS-CoV-2 target cells and putative zoonotic reservoirs. | |
| 700 | 1 | a Sun, J4 aut |
| 700 | 1 | a Zhu, JCu Karolinska Institutet4 aut |
| 700 | 1 | a Ding, XN4 aut |
| 700 | 1 | a Lan, TM4 aut |
| 700 | 1 | a Wang, XR4 aut |
| 700 | 1 | a Wu, WY4 aut |
| 700 | 1 | a Ou, ZH4 aut |
| 700 | 1 | a Zhu, LN4 aut |
| 700 | 1 | a Ding, PW4 aut |
| 700 | 1 | a Wang, HY4 aut |
| 700 | 1 | a Luo, LH4 aut |
| 700 | 1 | a Xiang, R4 aut |
| 700 | 1 | a Wang, XL4 aut |
| 700 | 1 | a Qiu, JY4 aut |
| 700 | 1 | a Wang, SY4 aut |
| 700 | 1 | a Li, HM4 aut |
| 700 | 1 | a Chai, CC4 aut |
| 700 | 1 | a Liang, LC4 aut |
| 700 | 1 | a An, FY4 aut |
| 700 | 1 | a Zhang, L4 aut |
| 700 | 1 | a Han, L4 aut |
| 700 | 1 | a Zhu, YX4 aut |
| 700 | 1 | a Wang, FY4 aut |
| 700 | 1 | a Yuan, YT4 aut |
| 700 | 1 | a Wu, WD4 aut |
| 700 | 1 | a Sun, CC4 aut |
| 700 | 1 | a Lu, HR4 aut |
| 700 | 1 | a Wu, JH4 aut |
| 700 | 1 | a Sun, XH4 aut |
| 700 | 1 | a Zhang, SH4 aut |
| 700 | 1 | a Sahu, SK4 aut |
| 700 | 1 | a Liu, P4 aut |
| 700 | 1 | a Xia, J4 aut |
| 700 | 1 | a Zhang, LJ4 aut |
| 700 | 1 | a Chen, HX4 aut |
| 700 | 1 | a Fang, DM4 aut |
| 700 | 1 | a Zeng, YY4 aut |
| 700 | 1 | a Wu, YQ4 aut |
| 700 | 1 | a Cui, ZH4 aut |
| 700 | 1 | a He, Q4 aut |
| 700 | 1 | a Jiang, SJ4 aut |
| 700 | 1 | a Ma, XY4 aut |
| 700 | 1 | a Feng, WM4 aut |
| 700 | 1 | a Xu, Y4 aut |
| 700 | 1 | a Li, F4 aut |
| 700 | 1 | a Liu, ZM4 aut |
| 700 | 1 | a Chen, L4 aut |
| 700 | 1 | a Chen, F4 aut |
| 700 | 1 | a Jin, X4 aut |
| 700 | 1 | a Qiu, W4 aut |
| 700 | 1 | a Wang, TJ4 aut |
| 700 | 1 | a Li, Y4 aut |
| 700 | 1 | a Xing, XM4 aut |
| 700 | 1 | a Yang, HM4 aut |
| 700 | 1 | a Xu, YC4 aut |
| 700 | 1 | a Hua, Y4 aut |
| 700 | 1 | a Liu, YH4 aut |
| 700 | 1 | a Liu, H4 aut |
| 700 | 1 | a Xu, X4 aut |
| 710 | 2 | a Karolinska Institutet4 org |
| 773 | 0 | t Nature communicationsd : Springer Science and Business Media LLCg 12:1, s. 7083-q 12:1<7083-x 2041-1723 |
| 856 | 4 | u https://www.nature.com/articles/s41467-021-27162-2.pdf |
| 856 | 4 8 | u http://kipublications.ki.se/Default.aspx?queryparsed=id:148325402 |
| 856 | 4 8 | u https://doi.org/10.1038/s41467-021-27162-2 |
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- Sun, J
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- Ou, ZH
- Zhu, LN
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- Wang, SY
- Li, HM
- Chai, CC
- Liang, LC
- An, FY
- Zhang, L
- Han, L
- Zhu, YX
- Wang, FY
- Yuan, YT
- Wu, WD
- Sun, CC
- Lu, HR
- Wu, JH
- Sun, XH
- Zhang, SH
- Sahu, SK
- Liu, P
- Xia, J
- Zhang, LJ
- Chen, HX
- Fang, DM
- Zeng, YY
- Wu, YQ
- Cui, ZH
- He, Q
- Jiang, SJ
- Ma, XY
- Feng, WM
- Xu, Y
- Li, F
- Liu, ZM
- Chen, L
- Chen, F
- Jin, X
- Qiu, W
- Wang, TJ
- Li, Y
- Xing, XM
- Yang, HM
- Xu, YC
- Hua, Y
- Liu, YH
- Liu, H
- Xu, X
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