WFRF:(Penninger J)
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| Fältnamn | Indikatorer | Metadata |
|---|---|---|
| 000 | 06498naa a2201441 4500 | |
| 001 | oai:gup.ub.gu.se/116971 | |
| 003 | SwePub | |
| 008 | 240528s2009 | |||||||||||000 ||eng| | |
| 009 | oai:prod.swepub.kib.ki.se:119038882 | |
| 024 | 7 | a https://gup.ub.gu.se/publication/1169712 URI |
| 024 | 7 | a https://doi.org/10.1038/cdd.2009.442 DOI |
| 024 | 7 | a http://kipublications.ki.se/Default.aspx?queryparsed=id:1190388822 URI |
| 040 | a (SwePub)gud (SwePub)ki | |
| 041 | a eng | |
| 042 | 9 SwePub | |
| 072 | 7 | a ref2 swepub-contenttype |
| 072 | 7 | a for2 swepub-publicationtype |
| 100 | 1 | a Galluzzi, L4 aut |
| 245 | 1 0 | a Guidelines for the use and interpretation of assays for monitoring cell death in higher eukaryotes. |
| 264 | c 2009-04-17 | |
| 264 | 1 | b Springer Science and Business Media LLC,c 2009 |
| 520 | a Cell death is essential for a plethora of physiological processes, and its deregulation characterizes numerous human diseases. Thus, the in-depth investigation of cell death and its mechanisms constitutes a formidable challenge for fundamental and applied biomedical research, and has tremendous implications for the development of novel therapeutic strategies. It is, therefore, of utmost importance to standardize the experimental procedures that identify dying and dead cells in cell cultures and/or in tissues, from model organisms and/or humans, in healthy and/or pathological scenarios. Thus far, dozens of methods have been proposed to quantify cell death-related parameters. However, no guidelines exist regarding their use and interpretation, and nobody has thoroughly annotated the experimental settings for which each of these techniques is most appropriate. Here, we provide a nonexhaustive comparison of methods to detect cell death with apoptotic or nonapoptotic morphologies, their advantages and pitfalls. These guidelines are intended for investigators who study cell death, as well as for reviewers who need to constructively critique scientific reports that deal with cellular demise. Given the difficulties in determining the exact number of cells that have passed the point-of-no-return of the signaling cascades leading to cell death, we emphasize the importance of performing multiple, methodologically unrelated assays to quantify dying and dead cells. | |
| 650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Medicinska och farmaceutiska grundvetenskaperx Mikrobiologi inom det medicinska området0 (SwePub)301092 hsv//swe |
| 650 | 7 | a MEDICAL AND HEALTH SCIENCESx Basic Medicinex Microbiology in the medical area0 (SwePub)301092 hsv//eng |
| 653 | a Apoptosis | |
| 653 | a Cell Death | |
| 653 | a Eukaryotic Cells | |
| 653 | a cytology | |
| 653 | a Flow Cytometry | |
| 653 | a Guidelines as Topic | |
| 653 | a Humans | |
| 653 | a Immunoblotting | |
| 653 | a Microscopy | |
| 653 | a Electron | |
| 653 | a Scanning | |
| 653 | a Microscopy | |
| 653 | a Fluorescence | |
| 653 | a Spectrometry | |
| 653 | a Fluorescence | |
| 700 | 1 | a Aaronson, S A4 aut |
| 700 | 1 | a Abrams, J4 aut |
| 700 | 1 | a Alnemri, E S4 aut |
| 700 | 1 | a Andrews, D W4 aut |
| 700 | 1 | a Baehrecke, E H4 aut |
| 700 | 1 | a Bazan, N G4 aut |
| 700 | 1 | a Blagosklonny, M V4 aut |
| 700 | 1 | a Blomgren, Klas,d 1963u Gothenburg University,Göteborgs universitet,Institutionen för neurovetenskap och fysiologi, sektionen för klinisk neurovetenskap och rehabilitering,Institutionen för kliniska vetenskaper,Institute of Neuroscience and Physiology, Department of Clinical Neuroscience and Rehabilitation,Institute of Clinical Sciences4 aut0 (Swepub:gu)xblokl |
| 700 | 1 | a Borner, C4 aut |
| 700 | 1 | a Bredesen, D E4 aut |
| 700 | 1 | a Brenner, C4 aut |
| 700 | 1 | a Castedo, M4 aut |
| 700 | 1 | a Cidlowski, J A4 aut |
| 700 | 1 | a Ciechanover, A4 aut |
| 700 | 1 | a Cohen, G M4 aut |
| 700 | 1 | a De Laurenzi, V4 aut |
| 700 | 1 | a De Maria, R4 aut |
| 700 | 1 | a Deshmukh, M4 aut |
| 700 | 1 | a Dynlacht, B D4 aut |
| 700 | 1 | a El-Deiry, W S4 aut |
| 700 | 1 | a Flavell, R A4 aut |
| 700 | 1 | a Fulda, S4 aut |
| 700 | 1 | a Garrido, C4 aut |
| 700 | 1 | a Golstein, P4 aut |
| 700 | 1 | a Gougeon, M-L4 aut |
| 700 | 1 | a Green, D R4 aut |
| 700 | 1 | a Gronemeyer, H4 aut |
| 700 | 1 | a Hajnóczky, G4 aut |
| 700 | 1 | a Hardwick, J M4 aut |
| 700 | 1 | a Hengartner, M O4 aut |
| 700 | 1 | a Ichijo, H4 aut |
| 700 | 1 | a Jäättelä, M4 aut |
| 700 | 1 | a Kepp, O4 aut |
| 700 | 1 | a Kimchi, A4 aut |
| 700 | 1 | a Klionsky, D J4 aut |
| 700 | 1 | a Knight, R A4 aut |
| 700 | 1 | a Kornbluth, S4 aut |
| 700 | 1 | a Kumar, S4 aut |
| 700 | 1 | a Levine, B4 aut |
| 700 | 1 | a Lipton, S A4 aut |
| 700 | 1 | a Lugli, E4 aut |
| 700 | 1 | a Madeo, F4 aut |
| 700 | 1 | a Malomi, W4 aut |
| 700 | 1 | a Marine, J-C W4 aut |
| 700 | 1 | a Martin, S J4 aut |
| 700 | 1 | a Medema, J P4 aut |
| 700 | 1 | a Mehlen, P4 aut |
| 700 | 1 | a Melino, G4 aut |
| 700 | 1 | a Moll, U M4 aut |
| 700 | 1 | a Morselli, E4 aut |
| 700 | 1 | a Nagata, S4 aut |
| 700 | 1 | a Nicholson, D W4 aut |
| 700 | 1 | a Nicotera, P4 aut |
| 700 | 1 | a Nuñez, G4 aut |
| 700 | 1 | a Oren, M4 aut |
| 700 | 1 | a Penninger, J4 aut |
| 700 | 1 | a Pervaiz, S4 aut |
| 700 | 1 | a Peter, M E4 aut |
| 700 | 1 | a Piacentini, M4 aut |
| 700 | 1 | a Prehn, J H M4 aut |
| 700 | 1 | a Puthalakath, H4 aut |
| 700 | 1 | a Rabinovich, G A4 aut |
| 700 | 1 | a Rizzuto, R4 aut |
| 700 | 1 | a Rodrigues, C M P4 aut |
| 700 | 1 | a Rubinsztein, D C4 aut |
| 700 | 1 | a Rudel, T4 aut |
| 700 | 1 | a Scorrano, L4 aut |
| 700 | 1 | a Simon, H-U4 aut |
| 700 | 1 | a Steller, H4 aut |
| 700 | 1 | a Tschopp, J4 aut |
| 700 | 1 | a Tsujimoto, Y4 aut |
| 700 | 1 | a Vandenabeele, P4 aut |
| 700 | 1 | a Vitale, I4 aut |
| 700 | 1 | a Vousden, K H4 aut |
| 700 | 1 | a Youle, R J4 aut |
| 700 | 1 | a Yuan, J4 aut |
| 700 | 1 | a Zhivotovsky, Bu Karolinska Institutet4 aut |
| 700 | 1 | a Kroemer, G4 aut |
| 710 | 2 | a Göteborgs universitetb Institutionen för neurovetenskap och fysiologi, sektionen för klinisk neurovetenskap och rehabilitering4 org |
| 773 | 0 | t Cell death and differentiationd : Springer Science and Business Media LLCg 16:8, s. 1093-107q 16:8<1093-107x 1476-5403x 1350-9047 |
| 856 | 4 | u https://www.nature.com/articles/cdd200944.pdf |
| 856 | 4 8 | u https://gup.ub.gu.se/publication/116971 |
| 856 | 4 8 | u https://doi.org/10.1038/cdd.2009.44 |
| 856 | 4 8 | u http://kipublications.ki.se/Default.aspx?queryparsed=id:119038882 |
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- Galluzzi, L
- Aaronson, S A
- Abrams, J
- Alnemri, E S
- Andrews, D W
- Baehrecke, E H
- visa fler...
- Bazan, N G
- Blagosklonny, M ...
- Blomgren, Klas, ...
- Borner, C
- Bredesen, D E
- Brenner, C
- Castedo, M
- Cidlowski, J A
- Ciechanover, A
- Cohen, G M
- De Laurenzi, V
- De Maria, R
- Deshmukh, M
- Dynlacht, B D
- El-Deiry, W S
- Flavell, R A
- Fulda, S
- Garrido, C
- Golstein, P
- Gougeon, M-L
- Green, D R
- Gronemeyer, H
- Hajnóczky, G
- Hardwick, J M
- Hengartner, M O
- Ichijo, H
- Jäättelä, M
- Kepp, O
- Kimchi, A
- Klionsky, D J
- Knight, R A
- Kornbluth, S
- Kumar, S
- Levine, B
- Lipton, S A
- Lugli, E
- Madeo, F
- Malomi, W
- Marine, J-C W
- Martin, S J
- Medema, J P
- Mehlen, P
- Melino, G
- Moll, U M
- Morselli, E
- Nagata, S
- Nicholson, D W
- Nicotera, P
- Nuñez, G
- Oren, M
- Penninger, J
- Pervaiz, S
- Peter, M E
- Piacentini, M
- Prehn, J H M
- Puthalakath, H
- Rabinovich, G A
- Rizzuto, R
- Rodrigues, C M P
- Rubinsztein, D C
- Rudel, T
- Scorrano, L
- Simon, H-U
- Steller, H
- Tschopp, J
- Tsujimoto, Y
- Vandenabeele, P
- Vitale, I
- Vousden, K H
- Youle, R J
- Yuan, J
- Zhivotovsky, B
- Kroemer, G
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