Multicenter Study of Cronobacter sakazakii Infections in Humans, Europe, 2017

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Fältnamn	Indikatorer	Metadata
000		05052naa a2200661 4500
001		oai:DiVA.org:uu-379029
003		SwePub
008		190311s2019 \| \|\|\|\|\|\|\|\|\|\|\|000 \|\|eng\|
024	7	a https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-3790292 URI
024	7	a https://doi.org/10.3201/eid2503.1816522 DOI
040		a (SwePub)uu
041		a engb eng
042		9 SwePub
072	7	a ref2 swepub-contenttype
072	7	a art2 swepub-publicationtype
100	1	a Lepuschitz, Sarahu Austrian Agcy Hlth & Food Safety, Vienna, Austria;Vienna Univ Technol, Vienna, Austria4 aut
245	1 0	a Multicenter Study of Cronobacter sakazakii Infections in Humans, Europe, 2017
264	1	b Centers for Disease Control and Prevention (CDC),c 2019
338		a print2 rdacarrier
520		a Cronobacter sakazakii has been documented as a cause of life-threating infections, predominantly in neonates. We conducted a multicenter study to assess the occurrence of C. sakazakii across Europe and the extent of clonality for outbreak detection. National coordinators representing 24 countries in Europe were requested to submit all human C. sakazakii isolates collected during 2017 to a study center in Austria. Testing at the center included species identification by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry, subtyping by whole-genome sequencing (WGS), and determination of antimicrobial resistance. Eleven countries sent 77 isolates, including 36 isolates from 2017 and 41 historical isolates. Fifty-nine isolates were confirmed as C. sakazakii by WGS, highlighting the challenge of correctly identifying Cronobacter spp. WGS-based typing revealed high strain diversity, indicating absence of multi-national outbreaks in 2017, but identified 4 previously unpublished historical outbreaks. WGS is the recommended method for accurate identification, typing, and detection of this pathogen.
650	7	a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Infektionsmedicin0 (SwePub)302092 hsv//swe
650	7	a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Infectious Medicine0 (SwePub)302092 hsv//eng
700	1	a Ruppitsch, Werneru Austrian Agcy Hlth & Food Safety, Vienna, Austria4 aut
700	1	a Pekard-Amenitsch, Shivau Austrian Agcy Hlth & Food Safety, Vienna, Austria4 aut
700	1	a Forsythe, Stephen J.u foodmicrobe.com, Keyworth, United Kingdom4 aut
700	1	a Cormican, Martinu Natl Univ Ireland, Galway, Ireland4 aut
700	1	a Mach, Robert L.u Vienna Univ Technol, Vienna, Austria4 aut
700	1	a Pierard, Denisu Univ Ziekenhuis Brussel, Brussels, Belgium4 aut
700	1	a Allerberger, Franzu Austrian Agcy Hlth & Food Safety, Vienna, Austria4 aut
700	1	a Allerberger, F.u Austrian Agcy Hlth & Food Safety, Vienna, Austria4 aut
700	1	a Andrasevic, A. Tambicu Univ Hosp Infect Dis, Zagreb, Croatia4 aut
700	1	a Balode, A.u Pauls Stradins Clin Univ Hosp, Riga, Latvia4 aut
700	1	a Barbut, F.u Hop St Antoine, Paris, France4 aut
700	1	a Codita, Irinau Carol Davila Univ Med & Pharm, Bucharest, Romania4 aut
700	1	a Connican, M.u Natl Univ Ireland Galway, Sch Med, Galway, Ireland4 aut
700	1	a Ferguson, C.u Victoria Hosp, Kirkcaldy, Scotland4 aut
700	1	a Heczko, P.u Jagiellonian Univ, Med Coll, Krakow, Poland4 aut
700	1	a Holy, O.u Palacky Univ, Dept Prevent Med, Olomouc, Czech Republic4 aut
700	1	a Kantardjiev, T.u Natl Ctr Infect & Parasit Dis, Sofia, Bulgaria4 aut
700	1	a Kuijper, E. J.u Leiden Univ, Med Ctr, Leiden, Netherlands4 aut
700	1	a Leegaard, T. M.u Akershus Univ Hosp, Lorenskog, Norway4 aut
700	1	a Peixe, L. M. , V4 aut
700	1	a Pierard, D.u Univ Ziekenhuis Brussel, Dept Lab Med, Brussels, Belgium4 aut
700	1	a Rautelin, Hilpiu Uppsala universitet,Klinisk mikrobiologi4 aut0 (Swepub:uu)hilra999
700	1	a Rupnik, M.u Nacl Lab Zdravje Okolje & Hrano, Maribor, Slovenia4 aut
700	1	a Schonning, K.u Hvidovre Univ Hosp, Hvidovre, Denmark4 aut
700	1	a Stephan, R.u Univ Zurich, Inst Food Safety & Hyg, Zurich, Switzerland4 aut
700	1	a Toniolo, A.u Univ Insubria, Varese, Italy4 aut
700	1	a Tosic, T.u Clin Ctr Serbia, Belgrade, Serbia4 aut
700	1	a Valdezate, S.u Inst Salud Carlos III, Madrid, Spain4 aut
700	1	a von Mueller, L.u Christophorus Kliniken GmbH, Coesfeld, Germany4 aut
700	1	a Zerva, L.u Attikon Hosp, Athens, Greece4 aut
700	1	a Zinieri-Panayide, B.u Gen Hosp, Paphos, Greece4 aut
710	2	a Austrian Agcy Hlth & Food Safety, Vienna, Austria;Vienna Univ Technol, Vienna, Austriab Austrian Agcy Hlth & Food Safety, Vienna, Austria4 org
773	0	t Emerging Infectious Diseasesd : Centers for Disease Control and Prevention (CDC)g 25:3, s. 515-522q 25:3<515-522x 1080-6040x 1080-6059
856	4	u https://doi.org/10.3201/eid2503.181652
856	4 8	u https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-379029
856	4 8	u https://doi.org/10.3201/eid2503.181652

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