Sökning: WFRF:(Rydberg Lennart 1944) > (2015-2019) > A positive pre-tran...
Fältnamn | Indikatorer | Metadata |
---|---|---|
000 | 04041naa a2200397 4500 | |
001 | oai:gup.ub.gu.se/221269 | |
003 | SwePub | |
008 | 240528s2015 | |||||||||||000 ||eng| | |
024 | 7 | a https://gup.ub.gu.se/publication/2212692 URI |
024 | 7 | a https://doi.org/10.15226/soji/3/3/001302 DOI |
040 | a (SwePub)gu | |
041 | a eng | |
042 | 9 SwePub | |
072 | 7 | a ref2 swepub-contenttype |
072 | 7 | a art2 swepub-publicationtype |
100 | 1 | a Gäbel, Markusu Gothenburg University,Göteborgs universitet,Institutionen för kliniska vetenskaper, Avdelningen för kirurgi,Institute of Clinical Sciences, Department of Surgery4 aut0 (Swepub:gu)xgabem |
245 | 1 0 | a A positive pre-transplant endothelial precursor cell crossmatch does not imply reduced long-term kindney graft function |
264 | c 2015-08-04 | |
264 | 1 | b Symbiosis Group,c 2015 |
520 | a A flow cytometric crossmatch test detecting antibodies specific for donor Endothelial Precursor Cells (EPC) was evaluated in a multicenter study in 2005-06. A Positive Pre-Transplant EPC Crossmatch (EPCXM) was associated with a higher frequency of early rejections and reduced renal function at three and six months. The long-term follow-up of all patients (n = 53/147) recruited at our center is reported. Patients were retrospectively evaluated regarding rejections, patient/ graft survival and renal function over a four-year follow-up. As for the whole multicenter study patient population, significantly more early rejections occurred in EPCXM positive compared to EPCXM negative patients (5/7 vs. 5/46, p = 0.002). The EPCXM positive group had higher SCr at three (183 vs. 118 μmol/l, p = 0.01) and six (172 vs. 124 μmol/l, p = 0.02) months compared to the EPCXM negative group, and measured Glomerular Filtration Rate (mGFR) was decreased in the EPCXM positive group at 6 months (50 vs. 29 ml/min, p = 0.01). SCr decreased and mGFR increased over time in the EPCXM negative group, while SCr increased slightly and mGFR decreased slightly in the EPCXM positive group eliminating the difference in renal function between the groups. A positive EPCXM pre-transplantation is associated with higher frequency of early graft rejections, but does not influence long (4 year) term renal function. | |
650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Kirurgi0 (SwePub)302122 hsv//swe |
650 | 7 | a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Surgery0 (SwePub)302122 hsv//eng |
653 | a antibody-mediated rejection | |
653 | a anti-endothelial cell antibodies | |
653 | a crossmatch | |
653 | a kidney graft function | |
653 | a non-HLA | |
700 | 1 | a AlMahri, Ayedau Gothenburg University,Göteborgs universitet,Institutionen för biomedicin, avdelningen för klinisk kemi och transfusionsmedicin,Institute of Biomedicine, Department of Clinical Chemistry and Transfusion Medicine4 aut |
700 | 1 | a Rydberg, Lennart,d 1944u Gothenburg University,Göteborgs universitet,Institutionen för biomedicin, avdelningen för klinisk kemi och transfusionsmedicin,Institute of Biomedicine, Department of Clinical Chemistry and Transfusion Medicine4 aut0 (Swepub:gu)xrydle |
700 | 1 | a Holgersson, Janu Gothenburg University,Göteborgs universitet,Institutionen för biomedicin, avdelningen för klinisk kemi och transfusionsmedicin,Institute of Biomedicine, Department of Clinical Chemistry and Transfusion Medicine4 aut0 (Swepub:gu)xholgj |
700 | 1 | a Breimer, Michael,d 1951u Gothenburg University,Göteborgs universitet,Institutionen för kliniska vetenskaper, Avdelningen för kirurgi,Institute of Clinical Sciences, Department of Surgery4 aut0 (Swepub:gu)xbremi |
710 | 2 | a Göteborgs universitetb Institutionen för kliniska vetenskaper, Avdelningen för kirurgi4 org |
773 | 0 | t SOJ Immunologyd : Symbiosis Groupg 3:3, s. 1-6q 3:3<1-6x 2372-0948 |
856 | 4 | u https://symbiosisonlinepublishing.com/immunology/immunology30.pdf |
856 | 4 8 | u https://gup.ub.gu.se/publication/221269 |
856 | 4 8 | u https://doi.org/10.15226/soji/3/3/00130 |
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