Sökning: WFRF:(Schwalbe H) > (2021) > 1H, 13C and 15N che...
Fältnamn | Indikatorer | Metadata |
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000 | 02870naa a2200577 4500 | |
001 | oai:prod.swepub.kib.ki.se:145712860 | |
003 | SwePub | |
008 | 240913s2021 | |||||||||||000 ||eng| | |
024 | 7 | a http://kipublications.ki.se/Default.aspx?queryparsed=id:1457128602 URI |
024 | 7 | a https://doi.org/10.1007/s12104-021-10007-w2 DOI |
040 | a (SwePub)ki | |
041 | a engb eng | |
042 | 9 SwePub | |
072 | 7 | a ref2 swepub-contenttype |
072 | 7 | a art2 swepub-publicationtype |
100 | 1 | a Schnieders, R4 aut |
245 | 1 0 | a 1H, 13C and 15N chemical shift assignment of the stem-loop 5a from the 5'-UTR of SARS-CoV-2 |
264 | c 2021-01-23 | |
264 | 1 | b Springer Science and Business Media LLC,c 2021 |
520 | a The SARS-CoV-2 (SCoV-2) virus is the causative agent of the ongoing COVID-19 pandemic. It contains a positive sense single-stranded RNA genome and belongs to the genus of Betacoronaviruses. The 5′- and 3′-genomic ends of the 30 kb SCoV-2 genome are potential antiviral drug targets. Major parts of these sequences are highly conserved among Betacoronaviruses and contain cis-acting RNA elements that affect RNA translation and replication. The 31 nucleotide (nt) long highly conserved stem-loop 5a (SL5a) is located within the 5′-untranslated region (5′-UTR) important for viral replication. SL5a features a U-rich asymmetric bulge and is capped with a 5′-UUUCGU-3′ hexaloop, which is also found in stem-loop 5b (SL5b). We herein report the extensive 1H, 13C and 15N resonance assignment of SL5a as basis for in-depth structural studies by solution NMR spectroscopy. | |
700 | 1 | a Peter, SA4 aut |
700 | 1 | a Banijamali, E4 aut |
700 | 1 | a Riad, M4 aut |
700 | 1 | a Altincekic, N4 aut |
700 | 1 | a Bains, JK4 aut |
700 | 1 | a Ceylan, B4 aut |
700 | 1 | a Furtig, B4 aut |
700 | 1 | a Grun, JT4 aut |
700 | 1 | a Hengesbach, M4 aut |
700 | 1 | a Hohmann, KF4 aut |
700 | 1 | a Hymon, D4 aut |
700 | 1 | a Knezic, B4 aut |
700 | 1 | a Oxenfarth, A4 aut |
700 | 1 | a Petzold, Ku Karolinska Institutet4 aut |
700 | 1 | a Qureshi, NS4 aut |
700 | 1 | a Richter, C4 aut |
700 | 1 | a Schlagnitweit, J4 aut |
700 | 1 | a Schlundt, A4 aut |
700 | 1 | a Schwalbe, H4 aut |
700 | 1 | a Stirnal, E4 aut |
700 | 1 | a Sudakov, A4 aut |
700 | 1 | a Vogele, J4 aut |
700 | 1 | a Wacker, A4 aut |
700 | 1 | a Weigand, JE4 aut |
700 | 1 | a Wirmer-Bartoschek, J4 aut |
700 | 1 | a Wohnert, J4 aut |
710 | 2 | a Karolinska Institutet4 org |
773 | 0 | t Biomolecular NMR assignmentsd : Springer Science and Business Media LLCg 15:1, s. 203-211q 15:1<203-211x 1874-270Xx 1874-2718 |
856 | 4 | u https://link.springer.com/content/pdf/10.1007/s12104-021-10007-w.pdf |
856 | 4 8 | u http://kipublications.ki.se/Default.aspx?queryparsed=id:145712860 |
856 | 4 8 | u https://doi.org/10.1007/s12104-021-10007-w |
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