Sökning: WFRF:(Seidelin Jakob B) > GM6001 Increases An...
Fältnamn | Indikatorer | Metadata |
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000 | 02422naa a2200361 4500 | |
001 | oai:lup.lub.lu.se:57f868cc-4c35-489b-b705-91f746c1f445 | |
003 | SwePub | |
008 | 160401s2015 | |||||||||||000 ||eng| | |
024 | 7 | a https://lup.lub.lu.se/record/77445572 URI |
024 | 7 | a https://doi.org/10.1089/sur.2014.2482 DOI |
040 | a (SwePub)lu | |
041 | a engb eng | |
042 | 9 SwePub | |
072 | 7 | a art2 swepub-publicationtype |
072 | 7 | a ref2 swepub-contenttype |
100 | 1 | a Rehn, Martinu Lund University,Lunds universitet,Kirurgi,Forskargrupper vid Lunds universitet,Surgery,Lund University Research Groups4 aut0 (Swepub:lu)med-mrr |
245 | 1 0 | a GM6001 Increases Anastomotic Leakage following Colonic Obstruction Possibly by Impeding Epithelialization. |
264 | 1 | b Mary Ann Liebert Inc,c 2015 |
520 | a Emergency operations performed on an obstructed colon are accompanied by an increased risk of anastomotic insufficiency. Tissue-destructive matrix metalloproteinase (MMP) activity is elevated in the obstructed colon and contributes to a loss of suture-holding submucosal collagen, which may be mediated by tumor necrosis factor (TNF)-α. Our aim was to study the effect of the non-selective MMP and TNF-α converting enzyme (TACE) inhibitor GM6001 (30 mg/kg) on anastomosis repair in obstructed left colon. GM6001 has been proved to be highly efficacious in elective anastomosis rodent models. | |
650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Kirurgi0 (SwePub)302122 hsv//swe |
650 | 7 | a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Surgery0 (SwePub)302122 hsv//eng |
700 | 1 | a Krarup, Peter-Martin4 aut |
700 | 1 | a Christensen, Lise H4 aut |
700 | 1 | a Seidelin, Jakob B4 aut |
700 | 1 | a Ågren, Magnus S4 aut |
700 | 1 | a Syk, Ingvaru Lund University,Lunds universitet,Kirurgi,Forskargrupper vid Lunds universitet,Surgery,Lund University Research Groups4 aut0 (Swepub:lu)kir-isy |
710 | 2 | a Kirurgib Forskargrupper vid Lunds universitet4 org |
773 | 0 | t Surgical Infectionsd : Mary Ann Liebert Incg 16:6, s. 702-708q 16:6<702-708x 1557-8674x 1096-2964 |
856 | 4 | u http://www.ncbi.nlm.nih.gov/pubmed/26171681?dopt=Abstracty FULLTEXT |
856 | 4 | u http://dx.doi.org/10.1089/sur.2014.248y FULLTEXT |
856 | 4 | u https://europepmc.org/articles/pmc4663637?pdf=render |
856 | 4 8 | u https://lup.lub.lu.se/record/7744557 |
856 | 4 8 | u https://doi.org/10.1089/sur.2014.248 |
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