Monitoring Adult Subglottic Stenosis With Spirometry and Dyspnea Index: A Novel Approach

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Ntouniadakis, Eleftherios,1983-Örebro universitet,Institutionen för medicinska vetenskaper,Department of Ear Nose and Throat (författare)

Monitoring Adult Subglottic Stenosis With Spirometry and Dyspnea Index : A Novel Approach

Artikel/kapitelEngelska2022

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2021-11-23
Sage Publications,2022
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LIBRIS-ID:oai:DiVA.org:oru-95568
https://urn.kb.se/resolve?urn=urn:nbn:se:oru:diva-95568URI
https://doi.org/10.1177/01945998211060817DOI
http://kipublications.ki.se/Default.aspx?queryparsed=id:148304620URI

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Språk:engelska
Sammanfattning på:engelska

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Ämneskategori:ref swepub-contenttype
Ämneskategori:art swepub-publicationtype

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Funding agency:Örebro County Council
OBJECTIVE: The aim was to examine the correlations among the anatomic Cotton-Myer classification, pulmonary function tests (PFTs), and patient-perceived dyspnea or dysphonia in patients with subglottic stenosis and identify measurements accurately reflecting treatment effects.STUDY DESIGN: Prospective cohort study.SETTING: Tertiary referral center.METHOD: Fifty-two adults receiving endoscopic treatment for isolated subglottic stenosis were consecutively included. Correlations were calculated among the preoperative Cotton-Myer scale, PFTs, the Dyspnea Index (DI), and the Voice Handicap Index. Receiver operating characteristic curves were determined for PFT, DI, and Voice Handicap Index pre- and postoperative measurements.RESULTS: The Cotton-Myer classification correlated weakly with peak expiratory flow (r = -0.35, P = .012), expiratory disproportion index (r = 0.32, P = .022), peak inspiratory flow (r = -0.32, P = .022), and total peak flow (r = -0.36, P = .01). The DI showed an excellent area under the curve (0.99, P < .001), and among PFTs, the expiratory disproportion index demonstrated the best area under the curve (0.89, P < .001), followed by total peak flow (0.88, P < .001), peak expiratory flow (0.87, P < .001), and peak inspiratory flow (0.84, P < .001). Patients treated endoscopically with balloon dilatation showed a 53% decrease in expiratory disproportion index (95% CI, 41%-66%; P < .001) and a 37% improvement in peak expiratory flow (95% CI, 31%-43%; P < .001).CONCLUSION: Expiratory disproportion index or peak expiratory flow combined with DI was a feasible measurement for the monitoring of adult subglottic stenosis. The percentage deterioration of peak expiratory flow and increase in expiratory disproportion index correlated significantly with a proportional percentage increase in DI.

Ämnesord och genrebeteckningar

MEDICIN OCH HÄLSOVETENSKAP Klinisk medicin Lungmedicin och allergi hsv//swe
MEDICAL AND HEALTH SCIENCES Clinical Medicine Respiratory Medicine and Allergy hsv//eng
Dyspnea index
expiratory disproportion index
functional assessment
peak expiratory flow
subglottic stenosis

Biuppslag (personer, institutioner, konferenser, titlar ...)

Sundh, Josefin,1972-Örebro universitet,Institutionen för medicinska vetenskaper,Department of Respiratory Medicine(Swepub:oru)jnsh (författare)
Von Beckerath, Mathias,1966-Department of Ear Nose and Throat, Faculty of Medicine and Health, Örebro University, Örebro, Sweden; Department of Clinical Sciences, Intervention and Technology, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden(Swepub:oru)msvt (författare)
Örebro universitetInstitutionen för medicinska vetenskaper (creator_code:org_t)

Sammanhörande titlar

Ingår i:Otolaryngology and head and neck surgery: Sage Publications167:3, s. 517-5230194-59981097-6817

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Av författaren/redakt...: Ntouniadakis, El ...; Sundh, Josefin, ...; Von Beckerath, M ...

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MEDICIN OCH HÄLSOVETENSKAP: MEDICIN OCH HÄLS ...; och Klinisk medicin; och Lungmedicin och ...

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Av lärosätet: Örebro universitet; Karolinska Institutet

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