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Very long-term follow-up of cognitive function in adults treated in infancy for hydrocephalus.

Lindquist, Barbro, 1950 (författare)
Persson, Eva-Karin, 1956 (författare)
Fernell, Elisabeth, 1948 (författare)
Gothenburg University,Göteborgs universitet,Institutionen för neurovetenskap och fysiologi, sektionen för psykiatri och neurokemi,Institute of Neuroscience and Physiology, Department of Psychiatry and Neurochemistry
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Uvebrant, Paul, 1951 (författare)
Gothenburg University,Göteborgs universitet,Institutionen för kliniska vetenskaper, Avdelningen för pediatrik,Institute of Clinical Sciences, Department of Pediatrics
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 (creator_code:org_t)
2010-10-23
2011
Engelska.
Ingår i: Child'S Nervous System. - : Springer Science and Business Media LLC. - 1433-0350 .- 0256-7040. ; 27:4, s. 597-601
  • Tidskriftsartikel (refereegranskat)
Abstract Ämnesord
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  • PURPOSE: The aim was to investigate the very long-term cognitive outcome in adults who had been shunt treated for hydrocephalus during their first year of life. METHODS: In a population-based series of 72 children born in 1967-1978 and shunt treated for infantile hydrocephalus, 43 were found to have a normal cognitive function when assessed at 6-17years of age. Twenty-five of them agreed to participate in a follow-up study of cognition at a mean age of 35years (range, 30-41years). The Wechsler Adult Intelligence Scale (WAIS-III) was used. RESULTS: The median full-scale IQ was 101 (range, 83-120), median verbal IQ was 104 (81-115) and performance IQ was 99 (80-127). The corresponding IQs in childhood in the 16 subjects who had been tested previously with the WISC were 101 (84-124), 108 (86-135), and 101 (73-124). Specific cognitive deficits were found for working memory and processing speed. Shunt complications did not affect IQ. CONCLUSION: This very long-term follow-up study of normally gifted children with hydrocephalus revealed that, as adults, they still had preserved cognitive functions despite recurrent shunt dysfunction. The results are encouraging and represent a tribute to neurosurgical intervention. Continued follow-up studies are needed since the etiological panorama and treatment procedures of children with hydrocephalus are changing over time.

Ämnesord

MEDICIN OCH HÄLSOVETENSKAP  -- Klinisk medicin -- Psykiatri (hsv//swe)
MEDICAL AND HEALTH SCIENCES  -- Clinical Medicine -- Psychiatry (hsv//eng)

Nyckelord

Adolescent
Adult
Cerebrospinal Fluid Shunts
Adverse effects
Child
Child
Preschool
Cognition
Follow-Up Studies
Humans
Hydrocephalus
Complications
Surgery
Infant
Wechsler Scales

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Lindquist, Barbr ...
Persson, Eva-Kar ...
Fernell, Elisabe ...
Uvebrant, Paul, ...
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MEDICIN OCH HÄLSOVETENSKAP
MEDICIN OCH HÄLS ...
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Child'S Nervous ...
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Göteborgs universitet

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