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LIBRIS Formathandbok  (Information om MARC21)
FältnamnIndikatorerMetadata
00003736naa a2200421 4500
001oai:gup.ub.gu.se/301915
003SwePub
008240528s2021 | |||||||||||000 ||eng|
0247 a https://gup.ub.gu.se/publication/3019152 URI
0247 a https://doi.org/10.1038/s41430-020-00849-32 DOI
040 a (SwePub)gu
041 a eng
042 9 SwePub
072 7a ref2 swepub-contenttype
072 7a art2 swepub-publicationtype
1001 a Kaesler, N.4 aut
2451 0a Low adherence to CKD-specific dietary recommendations associates with impaired kidney function, dyslipidemia, and inflammation
264 c 2021-02-02
264 1b Springer Science and Business Media LLC,c 2021
520 a Background/Objectives A diet following chronic kidney disease (CKD)-specific recommendations is considered essential for optimal management of patients with CKD. However, data on the adherence to these recommendations and its implications for health-relevant biomarkers are lacking. The objectives were to estimate adherence to CKD-specific dietary recommendations, to identify characteristics and lifestyle variables associated with poor adherence, and to investigate the relationship of adherence with biomarkers. Methods In this cross-sectional analysis, average dietary intake was estimated in 3193 participants with moderately severe CKD enrolled into the observational multicenter German CKD study using a food frequency questionnaire. A CKD diet score was developed to assess adherence to CKD-specific dietary recommendations based on intake of sodium, potassium, fiber, protein, sugar, and cholesterol. The associations of dietary adherence with characteristics, lifestyle variables, and biomarker levels were determined. Results Logistic regression analysis revealed younger age, higher body mass index, male gender, lower educational attainment, various lifestyle variables (cigarette smoking, infrequent alcohol consumption, low physical activity), and lower estimated glomerular filtrate rate associated with lower adherence to dietary recommendations. Low adherence to dietary recommendations was further associated with dyslipidemia, higher uric acid, and C-reactive protein levels. Associations between low dietary adherence and biomarkers were mostly driven by low intake of fiber and potassium, and high intake of sugar and cholesterol. Conclusions This study revealed differential characteristics and biomarkers associated with lower adherence to CKD-specific dietary recommendations. Promotion of CKD-specific dietary recommendations may help to mitigate the adverse prognosis in CKD patients.
650 7a MEDICIN OCH HÄLSOVETENSKAPx Hälsovetenskapx Näringslära0 (SwePub)303042 hsv//swe
650 7a MEDICAL AND HEALTH SCIENCESx Health Sciencesx Nutrition and Dietetics0 (SwePub)303042 hsv//eng
653 a Nutrition & Dietetics
7001 a Baid-Agrawal, Seema,d 1966u Gothenburg University,Göteborgs universitet,Institutionen för medicin,Institute of Medicine4 aut0 (Swepub:gu)xbaise
7001 a Grams, S.4 aut
7001 a Nadal, J.4 aut
7001 a Schmid, M.4 aut
7001 a Schneider, M. P.4 aut
7001 a Eckardt, K. U.4 aut
7001 a Floege, J.4 aut
7001 a Bergmann, M. M.4 aut
7001 a Schlieper, G.4 aut
7001 a Saritas, T.4 aut
7102 a Göteborgs universitetb Institutionen för medicin4 org
7730 t European Journal of Clinical Nutritiond : Springer Science and Business Media LLCg 75, s. 1389-1397q 75<1389-1397x 0954-3007x 1476-5640
8564 u https://www.nature.com/articles/s41430-020-00849-3.pdf
8564 8u https://gup.ub.gu.se/publication/301915
8564 8u https://doi.org/10.1038/s41430-020-00849-3

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