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Structural changes ...
Structural changes in the developing retina maintained in vitro.
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- Johansson, Kjell (författare)
- Lund University,Lunds universitet,Oftalmologi, Lund,Sektion IV,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Ophthalmology, Lund,Section IV,Department of Clinical Sciences, Lund,Faculty of Medicine
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- Ehinger, Berndt (författare)
- Lund University,Lunds universitet,Oftalmologi, Lund,Sektion IV,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Ophthalmology, Lund,Section IV,Department of Clinical Sciences, Lund,Faculty of Medicine
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(creator_code:org_t)
- Elsevier BV, 2005
- 2005
- Engelska.
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Ingår i: Vision Research. - : Elsevier BV. - 1878-5646 .- 0042-6989. ; 45:25-26, s. 3235-3243
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Abstract
Ämnesord
Stäng
- The present study examined the emergence of structural remodeling in explanted neonatal rat retina. Immunohistochemical analysis demonstrated signs of glial and neuronal remodeling after I I days in vitro and included the activation of Muller cells, the formation of ectopic neuropil areas and sprouting of photoreceptor terminals. We also observed that cholinergic and GABA-ergic amacrine cells displayed signs of disorganized laminations. These results demonstrate that retinal culturing initiates structural changes that show morphological similarities to glial and neuronal remodeling identified in retinitis pigmentosa retinas and experimentally detached retinas.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Oftalmologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Ophthalmology (hsv//eng)
Nyckelord
- Muller cells
- photoreceptor sprouting
- in vitro
- retina
- remodeling
Publikations- och innehållstyp
- art (ämneskategori)
- ref (ämneskategori)
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