SwePub
Sök i LIBRIS databas

  Utökad sökning

WFRF:(Jansson Sven Arne)
 

Sökning: WFRF:(Jansson Sven Arne) > Cost-Effectiveness ...

LIBRIS Formathandbok  (Information om MARC21)
FältnamnIndikatorerMetadata
00004254naa a2200505 4500
001oai:lup.lub.lu.se:4cf2662d-c2e8-4e7d-b83e-1b1a82019b73
003SwePub
008160401s2014 | |||||||||||000 ||eng|
0247 a https://lup.lub.lu.se/record/46145182 URI
0247 a https://doi.org/10.1016/j.jval.2014.03.17212 DOI
040 a (SwePub)lu
041 a engb eng
042 9 SwePub
072 7a art2 swepub-publicationtype
072 7a ref2 swepub-contenttype
1001 a Hoogendoorn, Martine4 aut
2451 0a Cost-Effectiveness Models for Chronic Obstructive Pulmonary Disease: Cross-Model Comparison of Hypothetical Treatment Scenarios
264 1b Elsevier BV,c 2014
338 a electronic2 rdacarrier
520 a Objectives To compare different chronic obstructive pulmonary disease (COPD) cost-effectiveness models with respect to structure and input parameters and to cross-validate the models by running the same hypothetical treatment scenarios. Methods COPD modeling groups simulated four hypothetical interventions with their model and compared the results with a reference scenario of no intervention. The four interventions modeled assumed 1) 20% reduction in decline in lung function, 2) 25% reduction in exacerbation frequency, 3) 10% reduction in all-cause mortality, and 4) all these effects combined. The interventions were simulated for a 5-year and lifetime horizon with standardization, if possible, for sex, age, COPD severity, smoking status, exacerbation frequencies, mortality due to other causes, utilities, costs, and discount rates. Furthermore, uncertainty around the outcomes of intervention four was compared. Results Seven out of nine contacted COPD modeling groups agreed to participate. The 5-year incremental cost-effectiveness ratios (ICERs) for the most comprehensive intervention, intervention four, was €17,000/quality-adjusted life-year (QALY) for two models, €25,000 to €28,000/QALY for three models, and €47,000/QALY for the remaining two models. Differences in the ICERs could mainly be explained by differences in input values for disease progression, exacerbation-related mortality, and all-cause mortality, with high input values resulting in low ICERs and vice versa. Lifetime results were mainly affected by the input values for mortality. The probability of intervention four to be cost-effective at a willingness-to-pay value of €50,000/QALY was 90% to 100% for five models and about 70% and 50% for the other two models, respectively. Conclusions Mortality was the most important factor determining the differences in cost-effectiveness outcomes between models.
650 7a MEDICIN OCH HÄLSOVETENSKAPx Hälsovetenskapx Hälso- och sjukvårdsorganisation, hälsopolitik och hälsoekonomi0 (SwePub)303012 hsv//swe
650 7a MEDICAL AND HEALTH SCIENCESx Health Sciencesx Health Care Service and Management, Health Policy and Services and Health Economy0 (SwePub)303012 hsv//eng
653 a COPD
653 a cost-effectiveness
653 a model
653 a validation
7001 a Feenstra, Talitha L4 aut
7001 a Asukai, Yumi4 aut
7001 a Borg, Sixtenu Lund University,Lunds universitet,Hälsoekonomi,Forskargrupper vid Lunds universitet,Health Economics,Lund University Research Groups4 aut0 (Swepub:lu)med-sxb
7001 a Hansen, Ryan N4 aut
7001 a Jansson, Sven-Arne4 aut
7001 a Samyshkin, Yevgeniy4 aut
7001 a Wacker, Margarethe4 aut
7001 a Briggs, Andrew H4 aut
7001 a Lloyd, Adam4 aut
7001 a Sullivan, Sean D4 aut
7001 a Rutten-van Mölken, Maureen P M H4 aut
7102 a Hälsoekonomib Forskargrupper vid Lunds universitet4 org
7730 t Value in Healthd : Elsevier BVg 17:5, s. 525-536q 17:5<525-536x 1098-3015
8564 u https://portal.research.lu.se/files/1591123/4729884.pdfx primaryx freey FULLTEXT
8564 u http://www.ncbi.nlm.nih.gov/pubmed/25128045?dopt=Abstracty FULLTEXT
8564 u http://dx.doi.org/10.1016/j.jval.2014.03.1721y FULLTEXT
8564 u http://www.valueinhealthjournal.com/article/S1098301514017823/pdf
8564 8u https://lup.lub.lu.se/record/4614518
8564 8u https://doi.org/10.1016/j.jval.2014.03.1721

Hitta via bibliotek

Till lärosätets databas

Kungliga biblioteket hanterar dina personuppgifter i enlighet med EU:s dataskyddsförordning (2018), GDPR. Läs mer om hur det funkar här.
Så här hanterar KB dina uppgifter vid användning av denna tjänst.

 
pil uppåt Stäng

Kopiera och spara länken för att återkomma till aktuell vy