Sökning: WFRF:(Lindahl Elisabeth) > Inverse relationshi...
Fältnamn | Indikatorer | Metadata |
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000 | 03669naa a2200373 4500 | |
001 | oai:DiVA.org:liu-74256 | |
003 | SwePub | |
008 | 120122s2001 | |||||||||||000 ||eng| | |
024 | 7 | a https://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-742562 URI |
024 | 7 | a https://doi.org/10.1159/0000480452 DOI |
040 | a (SwePub)liu | |
041 | a engb eng | |
042 | 9 SwePub | |
072 | 7 | a ref2 swepub-contenttype |
072 | 7 | a art2 swepub-publicationtype |
100 | 1 | a Järemo, Petteru Linköpings universitet,Kardiologi,Hälsouniversitetet4 aut0 (Swepub:liu)petja70 |
245 | 1 0 | a Inverse relationship between platelet density and reactivity alterations at coronary angiography |
264 | c 2001-06-15 | |
264 | 1 | a Basel :b S. Karger,c 2001 |
338 | a print2 rdacarrier | |
520 | a This work investigates relationships between platelet density and reactivity. 21 individuals subject to coronary angiography were studied. Peak platelet density was analyzed using a newly developed electronic device. The apparatus measures light transmission through test tubes containing density-separated platelets, thus allowing an estimation of the platelet distribution in the gradient. A flow cytometry technique was used for determining platelet reactivity after stimulating with ADP. Platelet counts, mean platelet volumes, peak platelet density and platelet reactivity were determined immediately before (day 1) and 24 h after cardiac catheterization (day 2). For all parameters changes during the day of angiography were compared with platelet density alterations. The subjects were divided into two groups according to density changes at angiography. Group 1 individuals showed density alterations (i.e. day 2 – day 1 value) ≥–8 × 10–5 kg/l. In contrast, group 2 subjects either displayed density changes <–8 × 10–5 kg/l or grossly disturbed platelet density patterns on day 2. Before angiography both groups had similar platelet counts and volumes. Then platelet reactivity when stimulating with ADP did not differ significantly between the two groups. After angiography, the number of fibrinogen-positive cells when stimulating with ADP rose by 6 ± 8% for group 2 patients. The corresponding figure for group 1 was –1 ± 6%. The difference was significant (p = 0.01). No such relationships were found when comparing density alterations and changes of platelet counts and volumes. We conclude that in this study platelet density alterations at coronary angiography are inversely related to variations of platelet reactivity. | |
653 | a MEDICINE | |
653 | a MEDICIN | |
700 | 1 | a Lindahl, Tomasu Linköpings universitet,Klinisk kemi,Hälsouniversitetet4 aut0 (Swepub:liu)tomli13 |
700 | 1 | a Fransson, Sven Göranu Linköpings universitet,Östergötlands Läns Landsting,Kardiologiska kliniken Thoraxradiologi,Hälsouniversitetet4 aut0 (Swepub:liu)svefr70 |
700 | 1 | a Milovanovic, Micha,d 1966-u Linköpings universitet,Kardiologi,Hälsouniversitetet4 aut0 (Swepub:liu)micmi83 |
700 | 1 | a Logander, Elisabethu Linköpings universitet,Kardiologi,Hälsouniversitetet4 aut |
700 | 1 | a Richter, Arinau Linköpings universitet,Kardiologi,Hälsouniversitetet4 aut0 (Swepub:liu)ariri12 |
710 | 2 | a Linköpings universitetb Kardiologi4 org |
773 | 0 | t Haemostasisd Basel : S. Kargerg 31:1, s. 55-60q 31:1<55-60x 0301-0147x 1423-0038 |
773 | 0 | t Pathophysiology of Haemostasis and Thrombosisd Basel : S. Kargerg 31:1, s. 55-60q 31:1<55-60x 1424-8832x 1424-8840 |
856 | 4 | u https://www.karger.com/Article/Pdf/48045 |
856 | 4 8 | u https://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-74256 |
856 | 4 8 | u https://doi.org/10.1159/000048045 |
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