SwePub
Sök i LIBRIS databas

  Utökad sökning

WFRF:(Lopez Jose Manuel)
 

Sökning: WFRF:(Lopez Jose Manuel) > Individualised, per...

LIBRIS Formathandbok  (Information om MARC21)
FältnamnIndikatorerMetadata
00011631naa a2200949 4500
001oai:DiVA.org:uu-533311
003SwePub
008240626s2024 | |||||||||||000 ||eng|
0247 a https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-5333112 URI
0247 a https://doi.org/10.1016/S2213-2600(23)00346-62 DOI
040 a (SwePub)uu
041 a engb eng
042 9 SwePub
072 7a ref2 swepub-contenttype
072 7a art2 swepub-publicationtype
1001 a Ferrando, Carlosu Inst Invest Biomed August Pi & Sunyer, Barcelona, Spain.;Inst Salud Carlos III, CIBER Enfermedades Resp, Madrid, Spain.;Inst Invest August Pi & Sunyer, Hosp Clin, Dept Anesthesiol & Crit Care, Barcelona 08036, Spain.4 aut
2451 0a Individualised, perioperative open-lung ventilation strategy during one-lung ventilation (iPROVE-OLV) :b a multicentre, randomised, controlled clinical trial
264 1b Elsevier,c 2024
338 a print2 rdacarrier
520 a Background It is uncertain whether individualisation of the perioperative open-lung approach (OLA) to ventilation reduces postoperative pulmonary complications in patients undergoing lung resection. We compared a perioperative individualised OLA (iOLA) ventilation strategy with standard lung-protective ventilation in patients undergoing thoracic surgery with one-lung ventilation. Methods This multicentre, randomised controlled trial enrolled patients scheduled for open or video-assisted thoracic surgery using one-lung ventilation in 25 participating hospitals in Spain, Italy, Turkey, Egypt, and Ecuador. Eligible adult patients (age >= 18 years) were randomly assigned to receive iOLA or standard lung-protective ventilation. Eligible patients (stratified by centre) were randomly assigned online by local principal investigators, with an allocation ratio of 1:1. Treatment with iOLA included an alveolar recruitment manoeuvre to 40 cm H2O of end-inspiratory pressure followed by individualised positive end-expiratory pressure (PEEP) titrated to best respiratory system compliance, and individualised postoperative respiratory support with high-flow oxygen therapy. Participants allocated to standard lungprotective ventilation received combined intraoperative 4 cm H2O of PEEP and postoperative conventional oxygen therapy. The primary outcome was a composite of severe postoperative pulmonary complications within the first 7 postoperative days, including atelectasis requiring bronchoscopy, severe respiratory failure, contralateral pneumothorax, early extubation failure (rescue with continuous positive airway pressure, non-invasive ventilation, invasive mechanical ventilation, or reintubation), acute respiratory distress syndrome, pulmonary infection, bronchopleural fistula, and pleural empyema. Due to trial setting, data obtained in the operating and postoperative rooms for routine monitoring were not blinded. At 24 h, data were acquired by an investigator blinded to group allocation. All analyses were performed on an intention-to-treat basis. This trial is registered with ClinicalTrials.gov, NCT03182062, and is complete. Findings Between Sept 11, 2018, and June 14, 2022, we enrolled 1380 patients, of whom 1308 eligible patients (670 [434 male, 233 female, and three with missing data] assigned to iOLA and 638 [395 male, 237 female, and six with missing data] to standard lung-protective ventilation) were included in the final analysis. The proportion of patients with the composite outcome of severe postoperative pulmonary complications within the first 7 postoperative days was lower in the iOLA group compared with the standard lung-protective ventilation group (40 [6%] vs 97 [15%], relative risk 0 center dot 39 [95% CI 0 center dot 28 to 0 center dot 56]), with an absolute risk difference of -9 center dot 23 (95% CI -12 center dot 55 to -5 center dot 92). Recruitment manoeuvre-related adverse events were reported in five patients. Interpretation Among patients subjected to lung resection under one-lung ventilation, iOLA was associated with a reduced risk of severe postoperative pulmonary complications when compared with conventional lung-protective ventilation. Funding Instituto de Salud Carlos III and the European Regional Development Funds. Copyright (c) 2023 Elsevier Ltd. All rights reserved.
650 7a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Anestesi och intensivvård0 (SwePub)302012 hsv//swe
650 7a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Anesthesiology and Intensive Care0 (SwePub)302012 hsv//eng
650 7a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Pediatrik0 (SwePub)302212 hsv//swe
650 7a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Pediatrics0 (SwePub)302212 hsv//eng
7001 a Carraminana, Albertu Hosp Clin Barcelona, Dept Anesthesiol & Crit Care, Barcelona, Spain.4 aut
7001 a Pineiro, Patricia4 aut
7001 a Mirabella, Luciau Univ Foggia, Dept Med & Surg Sci, Foggia, Italy.4 aut
7001 a Spadaro, Savinou Azienda Osped Univ Ferrara, Dept Anesthesiol & Crit Care, I-44100 Ferrara, Italy.4 aut
7001 a Libero, Julianu Navarrabiomed CHN UPNA, Red Invest Serv Sanitarios & Cronicidad REDISSEC, IdiSNA, Pamplona, Spain.4 aut
7001 a Ramasco, Fernandou Hosp Univ Princesa, Dept Anesthesiol & Crit Care, Madrid, Spain.4 aut
7001 a Scaramuzzo, Gaetanou Azienda Osped Univ Ferrara, Dept Anesthesiol & Crit Care, I-44100 Ferrara, Italy.4 aut
7001 a Cervantes, Oriolu Hosp Badalona Germans Trias & Pujol, Dept Anesthesiol & Crit Care, Barcelona, Spain.4 aut
7001 a Garutti, Ignaciou Hosp Univ Gregorio Maranon, Dept Anesthesiol & Crit Care, Madrid, Spain.4 aut
7001 a Parera, Anau Hosp Univ St Creu & St Pau, Dept Anesthesiol & Crit Care, Barcelona, Spain.4 aut
7001 a Argilaga, Martau Hosp Univ St Creu & St Pau, Dept Anesthesiol & Crit Care, Barcelona, Spain.4 aut
7001 a Herranz, Graciau Hosp Univ St Creu & St Pau, Dept Anesthesiol & Crit Care, Barcelona, Spain.4 aut
7001 a Unzueta, Carmenu Hosp Univ St Creu & St Pau, Dept Anesthesiol & Crit Care, Barcelona, Spain.4 aut
7001 a Vives, Marcu Hosp Univ Josep Trueta, Dept Anesthesiol & Crit Care, Girona, Spain.4 aut
7001 a Regi, Kevinu Hosp Univ Josep Trueta, Dept Anesthesiol & Crit Care, Girona, Spain.4 aut
7001 a Costa-Reverte, Martau Hosp Univ Bellvitge, Dept Anesthesiol & Crit Care, Barcelona, Spain.4 aut
7001 a Leal, Maria Sonsolesu Hosp Rivera Povisa, Vigo, Spain.4 aut
7001 a Garcia, Esther4 aut
7001 a Rodriguez-Perez, Aureliou Hosp Univ Gran Canaria Dr Negrin, Dept Anesthesiol & Crit Care, Gran Canarias, Spain.4 aut
7001 a Farina, Robertou Hosp Univ Gran Canaria Dr Negrin, Dept Anesthesiol & Crit Care, Gran Canarias, Spain.4 aut
7001 a Cabrera, Sergiou Hosp Univ Gran Canaria Dr Negrin, Dept Anesthesiol & Crit Care, Gran Canarias, Spain.4 aut
7001 a Guerra, Elisabethu Hosp Univ Princesa, Dept Anesthesiol & Crit Care, Madrid, Spain.;Hosp Univ Gran Canaria Dr Negrin, Dept Anesthesiol & Crit Care, Gran Canarias, Spain.4 aut
7001 a Gallego-Ligorit, Luciau Hosp Univ Miguel Servet, Dept Anesthesiol & Crit Care, Zaragoza, Spain.;Inst Invest Sanitaria Aragon IIS Aragon, Zaragoza, Spain.4 aut
7001 a Herrero-Izquierdo, Albau Hosp Univ Miguel Servet, Dept Anesthesiol & Crit Care, Zaragoza, Spain.;Inst Invest Sanitaria Aragon IIS Aragon, Zaragoza, Spain.4 aut
7001 a Valles-Torres, J.u Hosp Univ Miguel Servet, Dept Anesthesiol & Crit Care, Zaragoza, Spain.;Inst Invest Sanitaria Aragon IIS Aragon, Zaragoza, Spain.4 aut
7001 a Ramos, Silviau Hosp Univ Gregorio Maranon, Dept Anesthesiol & Crit Care, Madrid, Spain.4 aut
7001 a Lopez-Herrera, Danielu Hosp Univ Virgen Rocio, Dept Anesthesiol & Crit Care, Seville, Spain.4 aut
7001 a Matta, Manuel De Lau Hosp Univ Virgen Rocio, Dept Anesthesiol & Crit Care, Seville, Spain.4 aut
7001 a Gokhan, Sertcakacilaru Bakirkoy Dr Sadi Konuk Training & Res Hosp, Dept Anesthesiol & Crit Care, Istanbul, Turkiye.;Outcomes Res Consortium, Cleveland, OH USA.4 aut
7001 a Kucur, Evrimu Bakirkoy Dr Sadi Konuk Training & Res Hosp, Dept Anesthesiol & Crit Care, Istanbul, Turkiye.4 aut
7001 a Mugarra, Anau Hosp Clin Univ Valencia, Dept Anesthesiol & Crit Care, Valencia, Spain.4 aut
7001 a Soro, Marinau Hosp Clin Univ Valencia, Dept Anesthesiol & Crit Care, Valencia, Spain.4 aut
7001 a Garcia, Laurau Hosp Clin Univ Valencia, Dept Anesthesiol & Crit Care, Valencia, Spain.4 aut
7001 a Sastre, Jose Alfonsou Hosp Univ Salamanca, Dept Anesthesiol & Crit Care, Salamanca 37007, Spain.4 aut
7001 a Aguirre, Pilaru Hosp Alvaro Cunqueiro, Dept Anesthesiol & Crit Care, Vigo, Spain.4 aut
7001 a Salazar, Claudia Jimenau Hosp Univ Ntra Sra Candelaria, Dept Syst Anesthesiol & Crit Care, Santa Cruz De Tenerife, Spain.4 aut
7001 a Ramos, Maria Carolinau Hosp Univ Ntra Sra Candelaria, Dept Syst Anesthesiol & Crit Care, Santa Cruz De Tenerife, Spain.4 aut
7001 a Morocho, Diego Rolandou Hosp Eugenio Espejo, Dept Anesthesiol, Quito, Ecuador.4 aut
7001 a Trespalacios, Ramonu Hosp Univ Cent Asturias, Dept Anesthesiol & Crit Care, Oviedo, Spain.4 aut
7001 a Ezequiel-Fernandez, Felixu Hosp Univ Cent Asturias, Dept Anesthesiol & Crit Care, Oviedo, Spain.4 aut
7001 a Lamanna, Angellau Univ Foggia, Dept Med & Surg Sci, Foggia, Italy.4 aut
7001 a Cantatore, Leonarda Piau Univ Foggia, Dept Med & Surg Sci, Foggia, Italy.4 aut
7001 a Laforgia, Donatou Univ Foggia, Dept Med & Surg Sci, Foggia, Italy.4 aut
7001 a Bellas, Soledadu Hosp Univ Fdn Jimenez Diaz, Dept Anesthesiol & Crit Care, Madrid, Spain.4 aut
7001 a Lopez, Carlosu Hosp Univ Marques de Valdecilla, Dept Anesthesiol & Crit Care, Santander, Spain.4 aut
7001 a Navarro-Ripoll, Ricardu Hosp Clin Barcelona, Dept Anesthesiol & Crit Care, Barcelona, Spain.4 aut
7001 a Martinez, Samirau Hosp Clin Barcelona, Dept Anesthesiol & Crit Care, Barcelona, Spain.4 aut
7001 a Vallverdu, Jordiu Hosp Clin Barcelona, Dept Anesthesiol & Crit Care, Barcelona, Spain.4 aut
7001 a Jacas, Adrianau Hosp Clin Barcelona, Dept Anesthesiol & Crit Care, Barcelona, Spain.4 aut
7001 a Yepes-Temino, Maria Joseu Clin Univ Navarra, Dept Anesthesiol & Crit Care, Pamplona, Spain.4 aut
7001 a Belda, Francisco Javier4 aut
7001 a Tusman, Gerardou Hosp Privado Comunidad Mar Del Plata, Dept Anestesiol, Mar Del Plata, Buenos Aires, Argentina.4 aut
7001 a Suarez-Sipmann, Fernandou Uppsala universitet,Hedenstiernalaboratoriet,Inst Salud Carlos III, CIBER Enfermedades Resp CIBERES, Madrid, Spain.4 aut0 (Swepub:uu)fersi946
7001 a Villar, Jesusu CIBER Enfermedades Resp, Madrid, Spain.;Hosp Univ Dr Negrin, Las Palmas Gran Canaria, Spain.;St Michaels Hosp, Li Ka Shing Knowledge Inst Med Sci, Toronto, ON, Canada.4 aut
7102 a Inst Invest Biomed August Pi & Sunyer, Barcelona, Spain.;Inst Salud Carlos III, CIBER Enfermedades Resp, Madrid, Spain.;Inst Invest August Pi & Sunyer, Hosp Clin, Dept Anesthesiol & Crit Care, Barcelona 08036, Spain.b Hosp Clin Barcelona, Dept Anesthesiol & Crit Care, Barcelona, Spain.4 org
7730 t The Lancet Respiratory Medicined : Elsevierg 12:3, s. 195-206q 12:3<195-206x 2213-2600x 2213-2619
8564 8u https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-533311
8564 8u https://doi.org/10.1016/S2213-2600(23)00346-6

Hitta via bibliotek

Till lärosätets databas

Kungliga biblioteket hanterar dina personuppgifter i enlighet med EU:s dataskyddsförordning (2018), GDPR. Läs mer om hur det funkar här.
Så här hanterar KB dina uppgifter vid användning av denna tjänst.

 
pil uppåt Stäng

Kopiera och spara länken för att återkomma till aktuell vy