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Effects of Zinc, Ma...
Effects of Zinc, Magnesium, and Iron Ions on Bone Tissue Engineering
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- Chen, Zhixuan (författare)
- School of Medicine, Southeast University, Nanjing, China; Center for Stem Cell and Regenerative Medicine, Southeast University, Nanjing, China
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- Zhang, Wei (författare)
- School of Medicine, Southeast University, Nanjing, China; Center for Stem Cell and Regenerative Medicine, Southeast University, Nanjing, China; Jiangsu Key Laboratory for Biomaterials and Devices, Southeast University, Nanjing, China; China Orthopedic Regenerative Medicine Group (CORMed), Hangzhou, China
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- Wang, Mingyue (författare)
- School of Medicine, Southeast University, Nanjing, China; Center for Stem Cell and Regenerative Medicine, Southeast University, Nanjing, China
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- Backman, Ludvig J. (författare)
- Umeå universitet,Anatomi,Avdelningen för fysioterapi
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- Chen, Jialin (författare)
- School of Medicine, Southeast University, Nanjing, China; Center for Stem Cell and Regenerative Medicine, Southeast University, Nanjing, China; Jiangsu Key Laboratory for Biomaterials and Devices, Southeast University, Nanjing, China; China Orthopedic Regenerative Medicine Group (CORMed), Hangzhou, China
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(creator_code:org_t)
- 2022-05-31
- 2022
- Engelska.
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Ingår i: ACS Biomaterials Science & Engineering. - : American Chemical Society (ACS). - 2373-9878. ; 8:6, s. 2321-2335
- Relaterad länk:
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https://urn.kb.se/re...
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https://doi.org/10.1...
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Abstract
Ämnesord
Stäng
- Large-sized bone defects are a great challenge in clinics and considerably impair the quality of patients' daily life. Tissue engineering strategies using cells, scaffolds, and bioactive molecules to regulate the microenvironment in bone regeneration is a promising approach. Zinc, magnesium, and iron ions are natural elements in bone tissue and participate in many physiological processes of bone metabolism and therefore have great potential for bone tissue engineering and regeneration. In this review, we performed a systematic analysis on the effects of zinc, magnesium, and iron ions in bone tissue engineering. We focus on the role of these ions in properties of scaffolds (mechanical strength, degradation, osteogenesis, antibacterial properties, etc.). We hope that our summary of the current research achievements and our notifications of potential strategies to improve the effects of zinc, magnesium, and iron ions in scaffolds for bone repair and regeneration will find new inspiration and breakthroughs to inspire future research.
Ämnesord
- TEKNIK OCH TEKNOLOGIER -- Medicinteknik -- Medicinsk material- och protesteknik (hsv//swe)
- ENGINEERING AND TECHNOLOGY -- Medical Engineering -- Medical Materials (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Medicinsk bioteknologi -- Biomaterialvetenskap (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Medical Biotechnology -- Biomaterials Science (hsv//eng)
Nyckelord
- bone
- bone regeneration
- iron ions
- magnesium ions
- scaffolds
- tissue engineering
- zinc ions
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