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WFRF:(Nagy Zoltan)
 

Sökning: WFRF:(Nagy Zoltan) > Structural Correlat...

LIBRIS Formathandbok  (Information om MARC21)
FältnamnIndikatorerMetadata
00003804naa a2200541 4500
001oai:DiVA.org:su-34528
003SwePub
008100109s2009 | |||||||||||000 ||eng|
009oai:prod.swepub.kib.ki.se:119530010
0247 a https://urn.kb.se/resolve?urn=urn:nbn:se:su:diva-345282 URI
0247 a https://doi.org/10.1542/peds.2008-38012 DOI
0247 a http://kipublications.ki.se/Default.aspx?queryparsed=id:1195300102 URI
040 a (SwePub)sud (SwePub)ki
041 a engb eng
042 9 SwePub
072 7a ref2 swepub-contenttype
072 7a art2 swepub-publicationtype
1001 a Nagy, Zoltan4 aut
2451 0a Structural Correlates of Preterm Birth in the Adolescent Brain
264 c 2009-11-01
264 1b American Academy of Pediatrics,c 2009
338 a print2 rdacarrier
520 a OBJECTIVE: The Stockholm Neonatal Project involves a prospective,cross-sectional, population-based, cohort monitored for 12 to17 years after birth; it was started with the aim of investigatingthe long-term structural correlates of preterm birth and comparingfindings with reports on similar cohorts.METHODS: High-resolution anatomic and diffusion tensor imagingdata measuring diffusion in 30 directions were collected byusing a 1.5-T MRI scanner. A total of 143 adolescents (12.18–17.7years of age) participated in the study, including 74 formerlypreterm infants with birth weights of 1500 g (range: 645–1486g) and 69 term control subjects. The 2 groups were well matchedwith respect to demographic and socioeconomic data. The anatomicMRI data were used for calculation of total brain volumes andvoxelwise comparison of gray matter (GM) volumes. The diffusiontensor imaging data were used for voxelwise comparison of whitematter (WM) microstructural integrity.RESULTS: The formerly preterm individuals possessed 8.8% smallerGM volume and 9.4% smaller WM volume. The GM and WM volumesof individuals depended on gestational age and birth weight.The reduction in GM could be attributed bilaterally to the temporallobes, central, prefrontal, orbitofrontal, and parietal cortices,caudate nuclei, hippocampi, and thalami. Lower fractional anisotropywas observed in the posterior corpus callosum, fornix, and externalcapsules.CONCLUSIONS: Although preterm birth was found to be a risk factorregarding long-term structural brain development, the outcomewas milder than in previous reports. This may be attributableto differences in social structure and neonatal care practices.
650 7a SAMHÄLLSVETENSKAPx Psykologi0 (SwePub)5012 hsv//swe
650 7a SOCIAL SCIENCESx Psychology0 (SwePub)5012 hsv//eng
653 a preterm
653 a magnetic resonance imaging
653 a brain
653 a diffusion tensor imaging
653 a follow-up evaluation
653 a Psychology
653 a Psykologi
653 a Psychology
653 a psykologi
7001 a Ashburner, John4 aut
7001 a Andersson, Jesper4 aut
7001 a Jbabdi, Saad4 aut
7001 a Draganski, Bogdan4 aut
7001 a Skare, Stefanu Karolinska Institutet4 aut
7001 a Böhm, Birgittau Karolinska Institutet4 aut
7001 a Smedler, Ann-Charlotteu Stockholms universitet,Psykologiska institutionen4 aut0 (Swepub:su)acsr
7001 a Forssberg, Hansu Karolinska Institutet4 aut
7001 a Lagercrantz, Hugou Karolinska Institutet4 aut
7102 a Karolinska Institutetb Psykologiska institutionen4 org
7730 t Pediatricsd : American Academy of Pediatricsg 124:5, s. e964-e972q 124:5<e964-e972x 0031-4005x 1098-4275
8564 8u https://urn.kb.se/resolve?urn=urn:nbn:se:su:diva-34528
8564 8u https://doi.org/10.1542/peds.2008-3801
8564 8u http://kipublications.ki.se/Default.aspx?queryparsed=id:119530010

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