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Sökning: WFRF:(de la Cruz Lorena Fernández) > (2020-2024) > The association bet...

LIBRIS Formathandbok  (Information om MARC21)
FältnamnIndikatorerMetadata
00005874naa a2200457 4500
001oai:DiVA.org:oru-87643
003SwePub
008201127s2020 | |||||||||||000 ||eng|
0247 a https://urn.kb.se/resolve?urn=urn:nbn:se:oru:diva-876432 URI
040 a (SwePub)oru
041 a engb eng
042 9 SwePub
072 7a vet2 swepub-contenttype
072 7a art2 swepub-publicationtype
1001 a Krebs, Georginau MRC Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology & Neuroscience, King’s College London, London, United Kingdom; National and Specialist OCD and Related Disorders Clinic for Young People, South London and Maudsley NHS Foundation Trust, London, UK4 aut
2451 0a The association between body dysmorphic symptoms and suicidality among adolescents and young adults :b a genetically-informative study
264 1b Springer,c 2020
338 a print2 rdacarrier
500 a Funding Agencies:Swedish Council for Working Life, funds under ALF Agreement 2014-0322 ALFGBG-776031 340-2013-5867 2014-3831Swedish Research Council - MRC Clinical Research Training Fellowship MR/N001400/1Medical Research Council UK (MRC) MR/M021475/1
520 a Previous research indicates that body dysmorphic disorder (BDD) is associated with risk of suicidality. However, studies have relied on small and/or specialist samples and largely focused on adults, despite these difficulties commonly emerging in youth. Furthermore, the aetiology of the relationship remains unknown.Two independent twin samples were identified through the Child and Adolescent Twin Study in Sweden, at ages 18 (N = 6027) and 24 (N = 3454). Participants completed a self-report measure of BDD symptom severity. Young people and parents completed items assessing suicidal ideation and suicide attempts. Logistic regression models tested the association between continuous scores of BDD symptoms and suicidality outcomes. Bivariate genetic models examined the aetiology of the association between BDD symptoms and a suicidality composite at both ages.BDD symptoms were positively associated with suicidal ideation and suicide attempts at age 18 and 24. These associations generally remained significant after adjusting for depressive and anxiety symptoms. Genetic factors accounted for most of the covariance between BDD symptoms and suicidality (74.1% and 79.4% at ages 18 and 24, respectively), but with significant non-shared environmental influences (25.9% and 20.6% at ages 18 and 24, respectively).BDD symptoms are associated with substantial risk of suicidal ideation and behaviours in late adolescence and early adulthood. This relationship is largely explained by common genetic liability, but non-shared environmental effects are also significant and could provide opportunities for prevention among those at high-risk.
650 7a MEDICIN OCH HÄLSOVETENSKAPx Medicinska och farmaceutiska grundvetenskaperx Medicinsk genetik0 (SwePub)301072 hsv//swe
650 7a MEDICAL AND HEALTH SCIENCESx Basic Medicinex Medical Genetics0 (SwePub)301072 hsv//eng
653 a BDD
653 a Suicidal Ideation
653 a Suicide Attempts
653 a Twin Design
653 a Genetic
653 a Adolescence
7001 a de la Cruz, Lorena Fernandezu Centre for Psychiatry Research, Department of Clinical Neuro-science, Karolinska Institutet, & Stockholm Health Care Services, Stockholm County Council, Stockholm, Sweden4 aut
7001 a Rijsdijk, Fruhlingu MRC Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology & Neuroscience, King’s College London, London, United Kingdom4 aut
7001 a Rautio, Danielu Centre for Psychiatry Research, Department of Clinical Neuro-science, Karolinska Institutet, & Stockholm Health Care Services, Stockholm County Council, Stockholm, Sweden4 aut
7001 a Enander, Jesperu Centre for Psychiatry Research, Department of Clinical Neuro-science, Karolinska Institutet, & Stockholm Health Care Services, Stockholm County Council, Stockholm, Sweden4 aut
7001 a Rück, Christianu Centre for Psychiatry Research, Department of Clinical Neuro-science, Karolinska Institutet, & Stockholm Health Care Services, Stockholm County Council, Stockholm, Sweden4 aut
7001 a Lichtenstein, Paulu Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden4 aut
7001 a Lundström, Sebastianu Gillberg Neuropsychiatry Centre, Centre for Ethics, Law and Mental Health, University of Gothenburg, Sweden4 aut
7001 a Larsson, Henrik,d 1975-u Örebro universitet,Institutionen för medicinska vetenskaper,Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden4 aut0 (Swepub:oru)hiln
7001 a Eley, Thalia C.u MRC Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology & Neuroscience, King’s College London, London, United Kingdom4 aut
7001 a Mataix-Cols, Davidu Centre for Psychiatry Research, Department of Clinical Neuro-science, Karolinska Institutet, & Stockholm Health Care Services, Stockholm County Council, Stockholm, Sweden4 aut
7102 a MRC Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology & Neuroscience, King’s College London, London, United Kingdom; National and Specialist OCD and Related Disorders Clinic for Young People, South London and Maudsley NHS Foundation Trust, London, UKb Centre for Psychiatry Research, Department of Clinical Neuro-science, Karolinska Institutet, & Stockholm Health Care Services, Stockholm County Council, Stockholm, Sweden4 org
7730 t Behavior Geneticsd : Springerg 50:6, s. 462-462q 50:6<462-462x 0001-8244x 1573-3297
8564 8u https://urn.kb.se/resolve?urn=urn:nbn:se:oru:diva-87643

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