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| Fältnamn | Indikatorer | Metadata |
|---|---|---|
| 000 | 04388naa a2200457 4500 | |
| 001 | oai:DiVA.org:oru-85980 | |
| 003 | SwePub | |
| 008 | 200925s2020 | |||||||||||000 ||eng| | |
| 009 | oai:prod.swepub.kib.ki.se:145225923 | |
| 024 | 7 | a https://urn.kb.se/resolve?urn=urn:nbn:se:oru:diva-859802 URI |
| 024 | 7 | a https://doi.org/10.1136/thoraxjnl-2020-2146552 DOI |
| 024 | 7 | a http://kipublications.ki.se/Default.aspx?queryparsed=id:1452259232 URI |
| 040 | a (SwePub)orud (SwePub)ki | |
| 041 | a engb eng | |
| 042 | 9 SwePub | |
| 072 | 7 | a ref2 swepub-contenttype |
| 072 | 7 | a art2 swepub-publicationtype |
| 100 | 1 | a Caffrey Osvald, Emmau Paediatric Allergy and Pulmonology Unit, Astrid Lindgren Children's Hospital, Stockholm, Sweden; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden4 aut |
| 245 | 1 0 | a Asthma and all-cause mortality in children and young adults :b a population-based study |
| 264 | c 2020-09-22 | |
| 264 | 1 | b BMJ Publishing Group Ltd,c 2020 |
| 338 | a print2 rdacarrier | |
| 500 | a Funding Agency:Swedish Initiative for Research on Microdata in the Social and Medical Sciences (SIMSAM) 340-20135867 | |
| 520 | a BACKGROUND: Studies suggest an increased all-cause mortality among adults with asthma. We aimed to study the relationship between asthma in children and young adults and all-cause mortality, and investigate differences in mortality rate by also having a life-limiting condition (LLC) or by parental socioeconomic status (SES).METHODS: Included in this register-based study are 2 775 430 individuals born in Sweden between January 1986 and December 2012. We identified asthma cases using the National Patient Register (NPR) and the Prescribed Drug Register. Those with LLC were identified using the NPR. Parental SES at birth (income and education) was retrieved from Statistics Sweden. We estimated the association between asthma and all-cause mortality using a Cox proportional hazards regression model. Effect modification by LLC or parental SES was studied using interaction terms in the adjusted model.RESULTS: The adjusted hazard rate (adjHR) for all-cause mortality in asthma cases versus non-asthma cases was 1.46 (95% CI 1.33 to 1.62). The highest increased rate appeared to be for those aged 5-15 years. In persons with asthma and without LLC, the adjHR remained increased at 1.33 (95% CI 1.18 to 1.50), but differed (p=0.002) from those with asthma and LLC, with an adjHR of 1.87 (95% CI 1.57 to 2.22). Parental SES did not alter the association (income, p=0.55; education, p=0.83).CONCLUSION: This study shows that asthma is associated with an increased mortality in children and young adults regardless of LLC or parental SES. Further research is warranted to investigate the possible mechanisms for this association. | |
| 650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Hälsovetenskapx Folkhälsovetenskap, global hälsa, socialmedicin och epidemiologi0 (SwePub)303022 hsv//swe |
| 650 | 7 | a MEDICAL AND HEALTH SCIENCESx Health Sciencesx Public Health, Global Health, Social Medicine and Epidemiology0 (SwePub)303022 hsv//eng |
| 653 | a Asthma | |
| 653 | a asthma epidemiology | |
| 653 | a paediatric asthma | |
| 700 | 1 | a Bower, Hannahu Karolinska Institutet4 aut |
| 700 | 1 | a Lundholm, Ceciliau Karolinska Institutet4 aut |
| 700 | 1 | a Larsson, Henrik,d 1975-u Örebro universitet,Institutionen för medicinska vetenskaper,Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden4 aut0 (Swepub:oru)hiln |
| 700 | 1 | a Brew, Bronwyn K.u Karolinska Institutet4 aut |
| 700 | 1 | a Almqvist, Catarinau Karolinska Institutet4 aut |
| 710 | 2 | a Karolinska Institutetb Paediatric Allergy and Pulmonology Unit, Astrid Lindgren Children's Hospital, Stockholm, Sweden; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden4 org |
| 773 | 0 | t Thoraxd : BMJ Publishing Group Ltdg 75:12, s. 1040-1046q 75:12<1040-1046x 0040-6376x 1468-3296 |
| 856 | 4 | u https://doi.org/10.1136/thoraxjnl-2020-214655y Fulltext |
| 856 | 4 | u https://thorax.bmj.com/content/thoraxjnl/75/12/1040.full.pdf |
| 856 | 4 8 | u https://urn.kb.se/resolve?urn=urn:nbn:se:oru:diva-85980 |
| 856 | 4 8 | u https://doi.org/10.1136/thoraxjnl-2020-214655 |
| 856 | 4 8 | u http://kipublications.ki.se/Default.aspx?queryparsed=id:145225923 |
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