Sökning: WFRF:(Chapman John) > Single mimivirus pa...
Fältnamn | Indikatorer | Metadata |
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000 | 07718naa a2201501 4500 | |
001 | oai:DiVA.org:uu-146069 | |
003 | SwePub | |
008 | 110215s2011 | |||||||||||000 ||eng| | |
009 | oai:slubar.slu.se:33573 | |
024 | 7 | a https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-1460692 URI |
024 | 7 | a https://doi.org/10.1038/nature097482 DOI |
024 | 7 | a https://res.slu.se/id/publ/335732 URI |
040 | a (SwePub)uud (SwePub)slu | |
041 | a engb eng | |
042 | 9 SwePub | |
072 | 7 | a ref2 swepub-contenttype |
072 | 7 | a art2 swepub-publicationtype |
100 | 1 | a Seibert, M. Marvinu Uppsala universitet,Molekylär biofysik4 aut0 (Swepub:uu)masei255 |
245 | 1 0 | a Single mimivirus particles intercepted and imaged with an X-ray laser |
264 | c 2011-02-02 | |
264 | 1 | b Springer Science and Business Media LLC,c 2011 |
338 | a print2 rdacarrier | |
520 | a X-ray lasers offer new capabilities in understanding the structure of biological systems, complex materials and matter under extreme conditions(1-4). Very short and extremely bright, coherent X-ray pulses can be used to outrun key damage processes and obtain a single diffraction pattern from a large macromolecule, a virus or a cell before the sample explodes and turns into plasma(1). The continuous diffraction pattern of non-crystalline objects permits oversampling and direct phase retrieval(2). Here we show that high-quality diffraction data can be obtained with a single X-ray pulse from a noncrystalline biological sample, a single mimivirus particle, which was injected into the pulsed beam of a hard-X-ray free-electron laser, the Linac Coherent Light Source(5). Calculations indicate that the energy deposited into the virus by the pulse heated the particle to over 100,000 K after the pulse had left the sample. The reconstructed exit wavefront (image) yielded 32-nm full-period resolution in a single exposure and showed no measurable damage. The reconstruction indicates inhomogeneous arrangement of dense material inside the virion. We expect that significantly higher resolutions will be achieved in such experiments with shorter and brighter photon pulses focused to a smaller area. The resolution in such experiments can be further extended for samples available in multiple identical copies. | |
650 | 7 | a NATURVETENSKAPx Biologi0 (SwePub)1062 hsv//swe |
650 | 7 | a NATURAL SCIENCESx Biological Sciences0 (SwePub)1062 hsv//eng |
650 | 7 | a NATURVETENSKAPx Biologix Biofysik0 (SwePub)106032 hsv//swe |
650 | 7 | a NATURAL SCIENCESx Biological Sciencesx Biophysics0 (SwePub)106032 hsv//eng |
650 | 7 | a NATURVETENSKAPx Fysikx Atom- och molekylfysik och optik0 (SwePub)103022 hsv//swe |
650 | 7 | a NATURAL SCIENCESx Physical Sciencesx Atom and Molecular Physics and Optics0 (SwePub)103022 hsv//eng |
650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Medicinska och farmaceutiska grundvetenskaperx Cell- och molekylärbiologi0 (SwePub)301082 hsv//swe |
650 | 7 | a MEDICAL AND HEALTH SCIENCESx Basic Medicinex Cell and Molecular Biology0 (SwePub)301082 hsv//eng |
653 | a Biology | |
653 | a Biologi | |
700 | 1 | a Ekeberg, Tomasu Uppsala universitet,Molekylär biofysik4 aut0 (Swepub:uu)tomek611 |
700 | 1 | a Maia, Filipe R. N. C.u Uppsala universitet,Molekylär biofysik4 aut0 (Swepub:uu)cajca839 |
700 | 1 | a Svenda, Martinu Uppsala universitet,Molekylär biofysik4 aut0 (Swepub:uu)msv31659 |
700 | 1 | a Andreasson, Jakobu Uppsala universitet,Molekylär biofysik4 aut0 (Swepub:uu)jakan998 |
700 | 1 | a Joensson, Olofu Uppsala universitet,Molekylär biofysik4 aut |
700 | 1 | a Odic, Duskou Uppsala universitet,Molekylär biofysik4 aut |
700 | 1 | a Iwan, Biancau Uppsala universitet,Molekylär biofysik4 aut0 (Swepub:uu)biaiw419 |
700 | 1 | a Rocker, Andreau Uppsala universitet,Molekylär biofysik4 aut |
700 | 1 | a Westphal, Danielu Uppsala universitet,Molekylär biofysik4 aut0 (Swepub:uu)danwe345 |
700 | 1 | a Hantke, Maxu Uppsala universitet,Molekylär biofysik4 aut0 (Swepub:uu)maxha207 |
700 | 1 | a DePonte, Daniel P.4 aut |
700 | 1 | a Barty, Anton4 aut |
700 | 1 | a Schulz, Joachim4 aut |
700 | 1 | a Gumprecht, Lars4 aut |
700 | 1 | a Coppola, Nicola4 aut |
700 | 1 | a Aquila, Andrew4 aut |
700 | 1 | a Liang, Mengning4 aut |
700 | 1 | a White, Thomas A.4 aut |
700 | 1 | a Martin, Andrew4 aut |
700 | 1 | a Caleman, Carlu Uppsala universitet,Molekylär biofysik4 aut0 (Swepub:uu)cajca839 |
700 | 1 | a Stern, Stephan4 aut |
700 | 1 | a Abergel, Chantal4 aut |
700 | 1 | a Seltzer, Virginie4 aut |
700 | 1 | a Claverie, Jean-Michel4 aut |
700 | 1 | a Bostedt, Christoph4 aut |
700 | 1 | a Bozek, John D.4 aut |
700 | 1 | a Boutet, Sebastien4 aut |
700 | 1 | a Miahnahri, A. Alan4 aut |
700 | 1 | a Messerschmidt, Marc4 aut |
700 | 1 | a Krzywinski, Jacek4 aut |
700 | 1 | a Williams, Garth4 aut |
700 | 1 | a Hodgson, Keith O.4 aut |
700 | 1 | a Bogan, Michael J.4 aut |
700 | 1 | a Hampton, Christina Y.4 aut |
700 | 1 | a Sierra, Raymond G.4 aut |
700 | 1 | a Starodub, Dmitri4 aut |
700 | 1 | a Andersson, Ingeru Swedish University of Agricultural Sciences,Sveriges lantbruksuniversitet,Institutionen för molekylärbiologi,Department of Molecular Biology4 aut0 (Swepub:slu)47211 |
700 | 1 | a Bajt, Sasa4 aut |
700 | 1 | a Barthelmess, Miriam4 aut |
700 | 1 | a Spence, John C. H.4 aut |
700 | 1 | a Fromme, Petra4 aut |
700 | 1 | a Weierstall, Uwe4 aut |
700 | 1 | a Kirian, Richard4 aut |
700 | 1 | a Hunter, Mark4 aut |
700 | 1 | a Doak, R. Bruce4 aut |
700 | 1 | a Marchesini, Stefano4 aut |
700 | 1 | a Hau-Riege, Stefan P.4 aut |
700 | 1 | a Frank, Matthias4 aut |
700 | 1 | a Shoeman, Robert L.4 aut |
700 | 1 | a Lomb, Lukas4 aut |
700 | 1 | a Epp, Sascha W.4 aut |
700 | 1 | a Hartmann, Robert4 aut |
700 | 1 | a Rolles, Daniel4 aut |
700 | 1 | a Rudenko, Artem4 aut |
700 | 1 | a Schmidt, Carlo4 aut |
700 | 1 | a Foucar, Lutz4 aut |
700 | 1 | a Kimmel, Nils4 aut |
700 | 1 | a Holl, Peter4 aut |
700 | 1 | a Rudek, Benedikt4 aut |
700 | 1 | a Erk, Benjamin4 aut |
700 | 1 | a Hoemke, Andre4 aut |
700 | 1 | a Reich, Christian4 aut |
700 | 1 | a Pietschner, Daniel4 aut |
700 | 1 | a Weidenspointner, Georg4 aut |
700 | 1 | a Strueder, Lothar4 aut |
700 | 1 | a Hauser, Guenter4 aut |
700 | 1 | a Gorke, Hubert4 aut |
700 | 1 | a Ullrich, Joachim4 aut |
700 | 1 | a Schlichting, Ilme4 aut |
700 | 1 | a Herrmann, Sven4 aut |
700 | 1 | a Schaller, Gerhard4 aut |
700 | 1 | a Schopper, Florian4 aut |
700 | 1 | a Soltau, Heike4 aut |
700 | 1 | a Kuehnel, Kai-Uwe4 aut |
700 | 1 | a Andritschke, Robert4 aut |
700 | 1 | a Schroeter, Claus-Dieter4 aut |
700 | 1 | a Krasniqi, Faton4 aut |
700 | 1 | a Bott, Mario4 aut |
700 | 1 | a Schorb, Sebastian4 aut |
700 | 1 | a Rupp, Daniela4 aut |
700 | 1 | a Adolph, Marcus4 aut |
700 | 1 | a Gorkhover, Tais4 aut |
700 | 1 | a Hirsemann, Helmut4 aut |
700 | 1 | a Potdevin, Guillaume4 aut |
700 | 1 | a Graafsma, Heinz4 aut |
700 | 1 | a Nilsson, Björn4 aut |
700 | 1 | a Chapman, Henry N.4 aut |
700 | 1 | a Hajdu, Janosu Uppsala universitet,Molekylär biofysik4 aut0 (Swepub:uu)janohajd |
710 | 2 | a Uppsala universitetb Molekylär biofysik4 org |
710 | 2 | a Sveriges lantbruksuniversitet |
773 | 0 | t Natured : Springer Science and Business Media LLCg 470:7332, s. 78-81q 470:7332<78-81x 0028-0836x 1476-4687 |
856 | 4 | u https://bib-pubdb1.desy.de/record/92559/files/Mimi-final.pdf |
856 | 4 8 | u https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-146069 |
856 | 4 8 | u https://doi.org/10.1038/nature09748 |
856 | 4 8 | u https://res.slu.se/id/publ/33573 |
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