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LIBRIS Formathandbok  (Information om MARC21)
FältnamnIndikatorerMetadata
00005055naa a2200565 4500
001oai:gup.ub.gu.se/264483
003SwePub
008240910s2018 | |||||||||||000 ||eng|
0247 a https://gup.ub.gu.se/publication/2644832 URI
0247 a https://doi.org/10.1002/bjs.106802 DOI
040 a (SwePub)gu
041 a eng
042 9 SwePub
072 7a ref2 swepub-contenttype
072 7a art2 swepub-publicationtype
1001 a Park, Jenniferu Gothenburg University,Göteborgs universitet,Institutionen för kliniska vetenskaper, Avdelningen för kirurgi,Institute of Clinical Sciences, Department of Surgery4 aut0 (Swepub:gu)xparje
2451 0a Quality of life in a randomized trial of early closure of temporary ileostomy after rectal resection for cancer (EASY trial)
264 c 2017-11-23
264 1b Oxford University Press (OUP),c 2018
338 a electronic2 rdacarrier
520 a Background: A temporary ileostomy may reduce symptoms from anastomotic leakage after rectal cancer resection. Earlier results of the EASY trial showed that early closure of the temporary ileostomy was associated with significantly fewer postoperative complications. The aim of the present study was to compare health-related quality of life (HRQOL) following early versus late closure of a temporary ileostomy. Methods: Early closure of a temporary ileostomy (at 8-13 days) was compared with late closure (at more than 12 weeks) in a multicentre RCT (EASY) that included patients who underwent rectal resection for cancer. Inclusion of participants was made after index surgery. Exclusion criteria were signs of anastomotic leakage, diabetes mellitus, steroid treatment, and signs of postoperative complications at clinical evaluation 1-4 days after rectal resection. HRQOL was evaluated at 3, 6 and 12 months after resection using the European Organisation for Research and Treatment of Cancer (EORTC) questionnaires QLQ-C30 and QLQ-CR29 and Short Form 36 (SF-36 (R)). Results: There were 112 patients available for analysis. Response rates of the questionnaires were 82-95 per cent, except for EORTC QLQ-C30 at 12 months, to which only 54-55 per cent of the patients responded owing to an error in questionnaire distribution. There were no clinically significant differences in any questionnaire scores between the groups at 3, 6 or 12 months. Conclusion: Although the randomized study found that early closure of the temporary ileostomy was associated with significantly fewer complications, this clinical advantage had no effect on the patients' HRQOL.
650 7a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Cancer och onkologi0 (SwePub)302032 hsv//swe
650 7a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Cancer and Oncology0 (SwePub)302032 hsv//eng
650 7a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Kirurgi0 (SwePub)302122 hsv//swe
650 7a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Surgery0 (SwePub)302122 hsv//eng
653 a total mesorectal excision
653 a low anterior resection
653 a loop ileostomy
653 a defunctioning stoma
653 a colorectal-cancer
653 a eortc qlq-c30
653 a surgery
653 a questionnaire
653 a population
653 a sf-36
7001 a Danielsen, A. K.4 aut
7001 a Angenete, Eva,d 1972u Gothenburg University,Göteborgs universitet,Institutionen för kliniska vetenskaper, Avdelningen för kirurgi,Institute of Clinical Sciences, Department of Surgery4 aut0 (Swepub:gu)xangee
7001 a Bock, David,d 1976u Gothenburg University,Göteborgs universitet,Institutionen för kliniska vetenskaper, Avdelningen för kirurgi,Institute of Clinical Sciences, Department of Surgery4 aut0 (Swepub:gu)xbocda
7001 a Correa-Marinez, Adielau Gothenburg University,Göteborgs universitet,Institutionen för kliniska vetenskaper, Avdelningen för kirurgi,Institute of Clinical Sciences, Department of Surgery4 aut
7001 a Haglind, Eva,d 1947u Gothenburg University,Göteborgs universitet,Institutionen för kliniska vetenskaper, Avdelningen för kirurgi,Institute of Clinical Sciences, Department of Surgery4 aut0 (Swepub:gu)xhagev
7001 a Jansen, J. E.4 aut
7001 a Skullman, S.4 aut
7001 a Wedin, Anetteu Gothenburg University,Göteborgs universitet,Institutionen för kliniska vetenskaper, Avdelningen för kirurgi,Institute of Clinical Sciences, Department of Surgery4 aut0 (Swepub:gu)xwedan
7001 a Rosenberg, J.4 aut
7102 a Göteborgs universitetb Institutionen för kliniska vetenskaper, Avdelningen för kirurgi4 org
7730 t British Journal of Surgeryd : Oxford University Press (OUP)g 105:3, s. 244-251q 105:3<244-251x 0007-1323x 1365-2168
8564 u https://gup.ub.gu.se/publication/264483x primaryx freey FULLTEXT
8564 u https://bjssjournals.onlinelibrary.wiley.com/doi/pdfdirect/10.1002/bjs.10680
8564 8u https://gup.ub.gu.se/publication/264483
8564 8u https://doi.org/10.1002/bjs.10680

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