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CBD2 : A functional biomarker database for colorectal cancer

Zhang, Xueli (författare)
Linköpings universitet,Avdelningen för kirurgi, ortopedi och onkologi,Medicinska fakulteten,Region Östergötland, Onkologiska kliniken US,Southern Med Univ, Peoples R China; Southern Med Univ, Peoples R China; Guangdong Prov Key Lab Artificial Intelligence Med, Peoples R China
Li, Min (författare)
Medical Research Institute, Guangdong Provincial People's Hospital (Guangdong Academy of Medical Sciences), Southern Medical University, Guangzhou, China; MOE Key Laboratory of Geriatric Diseases and Immunology, Suzhou Key Laboratory of Pathogen Bioscience and Anti-infective Medicine, Department of Bioinformatics, Center for Systems Biology, School of Biology and Basic Medical Sciences, Suzhou Medical College of Soochow University, Suzhou, China,Southern Med Univ, Guangdong Prov Peoples Hosp, Med Res Inst, Guangdong Acad Med Sci, Guangzhou, Peoples R China.;Soochow Univ, Ctr Syst Biol, Sch Biol & Basic Med Sci, Suzhou Key Lab Pathogen Biosci & Antiinfect Med,De, Suzhou, Peoples R China.
Ye, S. (författare)
Department of Ultrasound, The Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, China; Department of Orthopaedics, The Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, China,Guangzhou Univ Chinese Med, Affiliated Hosp 2, Dept Ultrasound, Guangzhou, Peoples R China.;Guangzhou Univ Chinese Med, Affiliated Hosp 2, Dept Orthopaed, Guangzhou, Peoples R China.
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Shen, K. (författare)
Department of Critical Care Medicine and Institutes for Systems Genetics, Frontiers Science Center for Disease-related Molecular Network, West China Hospital, Sichuan University, Chengdu, China,Sichuan Univ, West China Hosp, Frontiers Sci Ctr Dis Related Mol Network, Dept Crit Care Med, Chengdu 610212, Peoples R China.;Sichuan Univ, West China Hosp, Inst Syst Genet, Frontiers Sci Ctr Dis related Mol Network, Chengdu, Peoples R China.
Yuan, H. (författare)
School of Laboratory Medicine and Bioengineering, Hangzhou Medical College, Hangzhou, China,Hangzhou Med Coll, Sch Lab Med & Bioengn, Hangzhou, Peoples R China.
Bakhtyar, S. (författare)
School of Medicine, Institute of Medical Sciences, Örebro University, Örebro, Sweden,Örebro Univ, Inst Med Sci, Sch Med, Örebro, Sweden.
Peng, Q. (författare)
Department of Radiotherapy and Oncology, The Second Affiliated Hospital of Soochow University, Suzhou, China,Soochow Univ, Affiliated Hosp 2, Dept Radiotherapy & Oncol, Suzhou, Peoples R China.
Liu, Yongsheng (författare)
Uppsala universitet,Cancerprecisionsmedicin,Uppsala Univ, Sweden
Wang, Yingying (författare)
Key Laboratory of Public Health Safety, School of Public Health, Fudan University, Shanghai, China,Fudan Univ, Sch Publ Hlth, Key Lab Publ Hlth Safety, Shanghai, Peoples R China.
Li, Manshi (författare)
Key Laboratory of Public Health Safety, School of Public Health, Fudan University, Shanghai, China,Fudan Univ, Sch Publ Hlth, Key Lab Publ Hlth Safety, Shanghai, Peoples R China.
Zhang, C. (författare)
Department of Otolaryngology, Guangzhou Women and Children's Medical Centre, Guangzhou, China,Guangzhou Women & Childrens Med Ctr, Dept Otolaryngol, Guangzhou, Peoples R China.
Wang, Yixin (författare)
MOE Key Laboratory of Geriatric Diseases and Immunology, Suzhou Key Laboratory of Pathogen Bioscience and Anti-infective Medicine, Department of Bioinformatics, Center for Systems Biology, School of Biology and Basic Medical Sciences, Suzhou Medical College of Soochow University, Suzhou, China; School of Medicine, The Chinese University of Hong Kong, Shenzhen, Shenzhen, China,Soochow Univ, Ctr Syst Biol, Sch Biol & Basic Med Sci, Suzhou Key Lab Pathogen Biosci & Antiinfect Med,De, Suzhou, Peoples R China.;Chinese Univ Hong Kong, Sch Med, Shenzhen, Shenzhen, Peoples R China.
Bai, X. (författare)
Department of Mathematics, University of California, San Diego, CA, United States,Univ Calif San Diego, Dept Math, San Diego, CA USA.
Liu, S. (författare)
Department of Ophthalmology, Guangdong Provincial People's Hospital (Guangdong Academy of Medical Sciences), Guangdong Eye Institute, Southern Medical University, Guangzhou, China,Southern Med Univ, Guangdong Prov Peoples Hosp, Guangdong Acad Med Sci, Guangdong Eye Inst,Dept Ophthalmol, Guangzhou, Peoples R China.
Zhao, Ke (författare)
Linköpings universitet,Avdelningen för kirurgi, ortopedi och onkologi,Medicinska fakulteten,Region Östergötland, Onkologiska kliniken US,Southern Med Univ, Peoples R China; Guangdong Prov Key Lab Artificial Intelligence Med, Peoples R China; Guangdong Prov Peoples Hosp, Peoples R China
Shen, B. (författare)
Institutes for Systems Genetics, Frontiers Science Center for Disease-Related Molecular Network, West China Hospital, Sichuan University, Chengdu, China,Sichuan Univ, West China Hosp, Inst Syst Genet, Frontiers Sci Ctr Dis Related Mol Network, Chengdu, Peoples R China.
Repsilber, Dirk, 1971- (författare)
Örebro universitet,Institutionen för medicinska vetenskaper,Örebro Univ, Inst Med Sci, Sch Med, Örebro, Sweden.
Hu, G. (författare)
MOE Key Laboratory of Geriatric Diseases and Immunology, Suzhou Key Laboratory of Pathogen Bioscience and Anti-infective Medicine, Department of Bioinformatics, Center for Systems Biology, School of Biology and Basic Medical Sciences, Suzhou Medical College of Soochow University, Suzhou, China,Soochow Univ, Ctr Syst Biol, Sch Biol & Basic Med Sci, Suzhou Key Lab Pathogen Biosci & Antiinfect Med,De, Suzhou, Peoples R China.
Zhang, Hong, 1957- (författare)
Örebro universitet,Institutionen för medicinska vetenskaper,Örebro Univ, Inst Med Sci, Sch Med, Örebro, Sweden.
Sun, Xiao-Feng (författare)
Linköpings universitet,Avdelningen för kirurgi, ortopedi och onkologi,Medicinska fakulteten,Region Östergötland, Onkologiska kliniken US
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 (creator_code:org_t)
John Wiley & Sons, 2024
2024
Engelska.
Ingår i: iMeta. - : John Wiley & Sons. - 2770-5986 .- 2770-596X. ; 3:1
Relaterad länk:
https://doi.org/10.1...
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https://uu.diva-port... (primary) (Raw object)
https://urn.kb.se/re...
https://doi.org/10.1...
https://urn.kb.se/re...
https://urn.kb.se/re...
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  • Tidskriftsartikel (refereegranskat)
Abstract Ämnesord
Stäng  
  • The rapidly evolving landscape of biomarkers for colorectal cancer (CRC) necessitates an integrative, updated repository. In response, we constructed the Colorectal Cancer Biomarker Database (CBD), which collected and displayed the curated biomedicine information for 870 CRC biomarkers in the previous study. Building on CBD, we have now developed CBD2, which includes information on 1569 newly reported biomarkers derived from different biological sources (DNA, RNA, protein, and others) and clinical applications (diagnosis, treatment, and prognosis). CBD2 also incorporates information on nonbiomarkers that have been identified as unsuitable for use as biomarkers in CRC. A key new feature of CBD2 is its network analysis function, by which users can investigate the visible and topological network between biomarkers and identify their relevant pathways. CBD2 also allows users to query a series of chemicals, drug combinations, or multiple targets, to enable multidrug, multitarget, multipathway analyses, toward facilitating the design of polypharmacological treatments for CRC. CBD2 is freely available at http://www.eyeseeworld.com/cbd.

Ämnesord

MEDICIN OCH HÄLSOVETENSKAP  -- Klinisk medicin -- Cancer och onkologi (hsv//swe)
MEDICAL AND HEALTH SCIENCES  -- Clinical Medicine -- Cancer and Oncology (hsv//eng)
NATURVETENSKAP  -- Biologi -- Bioinformatik och systembiologi (hsv//swe)
NATURAL SCIENCES  -- Biological Sciences -- Bioinformatics and Systems Biology (hsv//eng)

Nyckelord

biomarker
colorectal cancer
database
network analysis

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