Risk factors for suicide among patients with schizophrenia: a cohort study focused on cerebrospinal fluid levels of homovanillic acid and 5-hydroxyindoleacetic acid

Search: L773:1176 6328 > Risk factors for su...

Risk factors for suicide among patients with schizophrenia : a cohort study focused on cerebrospinal fluid levels of homovanillic acid and 5-hydroxyindoleacetic acid

Neider, Daniel (author): Uppsala universitet,Psykiatri, Akademiska sjukhuset

Lindström, Leif H. (author): Uppsala universitet,Psykiatri, Akademiska sjukhuset

(creator_code:org_t)

2016
2016
English.
In: Neuropsychiatric Disease and Treatment. - 1176-6328 .- 1178-2021. ; 12, s. 1711-1714

Related links:: https://uu.diva-port... (primary) (Raw object); show more...; https://urn.kb.se/re...; https://doi.org/10.2...; show less...

Abstract Subject headings

Background: The objective of this study was to investigate the association between 5-hydroxyindoleacetic acid (5-HIAA) and homovanillic acid (HVA) in cerebrospinal fluid (CSF), bullying, and later suicide among patients with schizophrenia. Methods: Ninety-nine patients with schizophrenia were included. Correlations of clinical factors, 5-HIAA and HVA, and later suicide were investigated. Results: Twelve patients committed suicide (12%) during a 28-year follow-up period. Later suicide was correlated to bullying in childhood (P=0.02) and a lower quotient of HVA/5-HIAA in CSF (P<0.05). Conclusion: Suicide in schizophrenia is related to childhood exposedness and CSF neurotransmitter levels.

About the subject

MEDICAL AND HEALTH SCIENCES: MEDICAL AND HEAL ...; and Clinical Medicin ...; and Neurology

MEDICAL AND HEALTH SCIENCES: MEDICAL AND HEAL ...; and Clinical Medicin ...; and Psychiatry

Kungliga biblioteket hanterar dina personuppgifter i enlighet med EU:s dataskyddsförordning (2018), GDPR. Läs mer om hur det funkar här.
Så här hanterar KB dina uppgifter vid användning av denna tjänst.