A unique virus release mechanism in the Archaea

↓ Direkt till sidans innehåll
↓ Direkt till sidans sekundära innehåll (sidomenyn)

Sökning: WFRF:(Karlsson Patrick) > A unique virus rele...

LIBRIS Formathandbok (Information om MARC21)

Fältnamn	Indikatorer	Metadata
000		03018naa a2200481 4500
001		oai:DiVA.org:uu-128369
003		SwePub
008		100720s2009 \| \|\|\|\|\|\|\|\|\|\|\|000 \|\|eng\|
024	7	a https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-1283692 URI
024	7	a https://doi.org/10.1073/pnas.09012381062 DOI
040		a (SwePub)uu
041		a engb eng
042		9 SwePub
072	7	a ref2 swepub-contenttype
072	7	a art2 swepub-publicationtype
100	1	a Bize, Ariane4 aut
245	1 0	a A unique virus release mechanism in the Archaea
264		c 2009-07-07
264	1	b Proceedings of the National Academy of Sciences,c 2009
338		a print2 rdacarrier
520		a Little is known about the infection cycles of viruses infecting cells from Archaea, the third domain of life. Here, we demonstrate that the virions of the archaeal Sulfolobus islandicus rod-shaped virus 2 (SIRV2) are released from the host cell through a mechanism, involving the formation of specific cellular structures. Large pyramidal virus-induced protrusions transect the cell envelope at several positions, rupturing the S-layer; they eventually open out, thus creating large apertures through which virions escape the cell. We also demonstrate that massive degradation of the host chromosomes occurs because of virus infection, and that virion assembly occurs in the cytoplasm. Furthermore, intracellular viral DNA is visualized by flow cytometry. The results show that SIRV2 is a lytic virus, and that the host cell dies as a consequence of elaborated mechanisms orchestrated by the virus. The generation of specific cellular structures for a distinct step of virus life cycle is known in eukaryal virus-host systems but is unprecedented in cells from other domains.
650	7	a NATURVETENSKAPx Biologi0 (SwePub)1062 hsv//swe
650	7	a NATURAL SCIENCESx Biological Sciences0 (SwePub)1062 hsv//eng
653		a lysis
653		a virus factory
653		a hyperthermophile
653		a infection cycle
653		a Biology
653		a Biologi
700	1	a Karlsson, Erik A.u Uppsala universitet,Molekylär evolution4 aut
700	1	a Ekefjärd, Karinu Uppsala universitet,Molekylär evolution4 aut
700	1	a Quax, F.4 aut
700	1	a Pina, Mery4 aut
700	1	a Prevost, Marie-Christine4 aut
700	1	a Forterre, Patrick4 aut
700	1	a Tenaillon, Olivier4 aut
700	1	a Bernander, Rolfu Uppsala universitet,Molekylär evolution4 aut0 (Swepub:uu)rbe03860
700	1	a Prangishvili, David4 aut
710	2	a Uppsala universitetb Molekylär evolution4 org
773	0	t Proceedings of the National Academy of Sciences of the United States of Americad : Proceedings of the National Academy of Sciencesg 106:27, s. 11306-11311q 106:27<11306-11311x 0027-8424x 1091-6490
856	4	u http://www.pnas.org/content/106/27/11306.full.pdf
856	4 8	u https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-128369
856	4 8	u https://doi.org/10.1073/pnas.0901238106

Hitta via bibliotek

Proceedings of the National Academy of Sciences of the United States of America (Sök värdpublikationen i LIBRIS)

Till lärosätets databas

Hitta mer i SwePub

Av författaren/redakt...: Bize, Ariane; Karlsson, Erik A ...; Ekefjärd, Karin; Quax, F.; Pina, Mery; Prevost, Marie-C ...; visa fler...; Forterre, Patric ...; Tenaillon, Olivi ...; Bernander, Rolf; Prangishvili, Da ...; visa färre...

Om ämnet

NATURVETENSKAP: NATURVETENSKAP; och Biologi

Artiklar i publikationen: Proceedings of t ...

Av lärosätet: Uppsala universitet

Sök utanför SwePub

Sök vidare i:: Google; Google Book Search; Google Scholar

Kungliga biblioteket hanterar dina personuppgifter i enlighet med EU:s dataskyddsförordning (2018), GDPR. Läs mer om hur det funkar här.
Så här hanterar KB dina uppgifter vid användning av denna tjänst.

LIBRIS.kb.se