Reference Intervals for Fecal Calprotectin in Adults Using Two Different Extraction Methods in the Uppsala-SCAPIS Cohort

↓ Direkt till sidans innehåll
↓ Direkt till sidans sekundära innehåll (sidomenyn)

Search: WFRF:(Larsson Johan 1979 ) > (2015-2019) > Reference Intervals...

LIBRIS Formathandbok (Information om MARC21)

Details
MARC

Fältnamn	Indikatorer	Metadata
000		04092naa a2200445 4500
001		oai:DiVA.org:uu-329204
003		SwePub
008		170914s2017 \| \|\|\|\|\|\|\|\|\|\|\|000 \|\|eng\|
009		oai:prod.swepub.kib.ki.se:136617591
024	7	a https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-3292042 URI
024	7	a https://doi.org/10.7754/Clin.Lab.2017.1704122 DOI
024	7	a http://kipublications.ki.se/Default.aspx?queryparsed=id:1366175912 URI
040		a (SwePub)uud (SwePub)ki
041		a engb eng
042		9 SwePub
072	7	a ref2 swepub-contenttype
072	7	a art2 swepub-publicationtype
100	1	a Fall, Tove,d 1979-u Uppsala universitet,Molekylär epidemiologi4 aut0 (Swepub:uu)tovfa878
245	1 0	a Reference Intervals for Fecal Calprotectin in Adults Using Two Different Extraction Methods in the Uppsala-SCAPIS Cohort
264	1	c 2017
338		a print2 rdacarrier
520		a Background: Fecal calprotectin measurement is generally recommended to exclude inflammatory bowel disease (IBD) in patients with suspected IBD. A problem with the fecal calprotectin assays so far has been the rather long test-turnaround times. Recently a particle enhanced turbidimetric immunoassay (PETIA) for fecal calprotectin with assay times of approximately 10 minutes has been introduced on the European market. The aim of this study was to define reference intervals for adults with this new fecal calprotectin PETIA using two different extraction methods. Methods: Samples were collected from 382 healthy individuals from the Swedish CArdioPulmonary bioImage Study (SCAPIS) Uppsala cohort in the age range 50 - 65 years. 202 samples were processed with CALEX® Cap extraction device (BÜHLMANN, Schönenbuch, Switzerland) and 180 samples were extracted using weighed samples. The extracted samples were analyzed on a Mindray BS-380 using the fCal Turbo PETIA reagent (BÜHLMANN). Results: The calculated reference values for the Calex device were < 199 µg/g for the whole cohort, < 184 µg/g for females, and < 215 µg/g for males, while the corresponding values for weighed samples were < 153 µg/g for the whole cohort, < 141 µg/g for females, and < 215 µg/g for males. There were no significant statistical differences for calprotectin levels in males and females. Conclusions: The CALEX device yielded slightly higher calprotectin values. As there were no significant gender differences, the study indicates gender independent reference intervals of < 199 µg/g feces for the CALEX device and < 153 µg/g feces for weighed samples in patients in the 50 - 65 year age range.
650	7	a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Gastroenterologi0 (SwePub)302132 hsv//swe
650	7	a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Gastroenterology and Hepatology0 (SwePub)302132 hsv//eng
650	7	a MEDICIN OCH HÄLSOVETENSKAPx Medicinsk bioteknologix Biomedicinsk laboratorievetenskap/teknologi0 (SwePub)304022 hsv//swe
650	7	a MEDICAL AND HEALTH SCIENCESx Medical Biotechnologyx Biomedical Laboratory Science/Technology0 (SwePub)304022 hsv//eng
653		a biological markers
653		a calprotectin
653		a feces
653		a inflammatory bowel diseases
653		a method validation
700	1	a Mandic-Havelka, Aleksandrau Karolinska Univ Hosp, Karolinska Inst & Clin Chem, Dept Mol Med & Surg4 aut
700	1	a Helmersson Karlqvist, Johannau Uppsala universitet,Klinisk kemi4 aut0 (Swepub:uu)johahelm
700	1	a Sundström, Johan,c Professor,d 1971-u Uppsala universitet,Uppsala kliniska forskningscentrum (UCR),Klinisk epidemiologi4 aut0 (Swepub:uu)johasund
700	1	a Larsson, Andersu Uppsala universitet,Klinisk kemi4 aut0 (Swepub:uu)andlarss
710	2	a Uppsala universitetb Molekylär epidemiologi4 org
773	0	t Clinical Laboratoryg 63:9, s. 1493-1496q 63:9<1493-1496x 1433-6510
856	4 8	u https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-329204
856	4 8	u https://doi.org/10.7754/Clin.Lab.2017.170412
856	4 8	u http://kipublications.ki.se/Default.aspx?queryparsed=id:136617591

Find in a library

Clinical Laboratory (Search for host publication in LIBRIS)

To the university's database

Find more in SwePub

By the author/editor: Fall, Tove, 1979 ...; Mandic-Havelka, ...; Helmersson Karlq ...; Sundström, Johan ...; Larsson, Anders

About the subject

MEDICAL AND HEALTH SCIENCES: MEDICAL AND HEAL ...; and Clinical Medicin ...; and Gastroenterology ...

MEDICAL AND HEALTH SCIENCES: MEDICAL AND HEAL ...; and Medical Biotechn ...; and Biomedical Labor ...

Articles in the publication: Clinical Laborat ...

By the university: Uppsala University; Karolinska Institutet

Search outside SwePub

Extend your search to:: Google; Google Book Search; Google Scholar

Kungliga biblioteket hanterar dina personuppgifter i enlighet med EU:s dataskyddsförordning (2018), GDPR. Läs mer om hur det funkar här.
Så här hanterar KB dina uppgifter vid användning av denna tjänst.

LIBRIS.kb.se