Search: WFRF:(de la Cruz Lorena Fernández) > Insomnia in Tourett...
Fältnamn | Indikatorer | Metadata |
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000 | 04814naa a2200493 4500 | |
001 | oai:DiVA.org:oru-95179 | |
003 | SwePub | |
008 | 211027s2022 | |||||||||||000 ||eng| | |
009 | oai:prod.swepub.kib.ki.se:147930859 | |
024 | 7 | a https://urn.kb.se/resolve?urn=urn:nbn:se:oru:diva-951792 URI |
024 | 7 | a https://doi.org/10.1002/mds.288422 DOI |
024 | 7 | a http://kipublications.ki.se/Default.aspx?queryparsed=id:1479308592 URI |
040 | a (SwePub)orud (SwePub)ki | |
041 | a engb eng | |
042 | 9 SwePub | |
072 | 7 | a ref2 swepub-contenttype |
072 | 7 | a art2 swepub-publicationtype |
100 | 1 | a Isomura, Kayokou Karolinska Institutet4 aut |
245 | 1 0 | a Insomnia in Tourette Syndrome and Chronic Tic Disorder |
264 | c 2021-10-24 | |
264 | 1 | b John Wiley & Sons,c 2022 |
338 | a print2 rdacarrier | |
520 | a BACKGROUND: Insomnia is common in Tourette syndrome (TS) and chronic tic disorder (CTD), but precise prevalence estimates are lacking.OBJECTIVE: In this Swedish register-based cohort study, we estimated the prevalence of insomnia in TS/CTD and quantified the magnitude of this association, accounting for familial confounders and relevant somatic and psychiatric comorbidities.METHODS: Of 10,444,702 individuals living in Sweden during the period from 1997 to 2013, 5877 had a diagnosis of TS/CTD and were compared to unexposed individuals from the general population on the presence of insomnia using logistic regression models.RESULTS: Individuals with TS/CTD had a period prevalence of insomnia of 32.16%, compared to 13.70% of the unexposed population. This translated into a 6.7-fold increased likelihood of insomnia in TS/CTD (odds ratio adjusted [aOR] for sex, birth year, birth country, and somatic disorders = 6.74; 95% confidence interval [CI], 6.37-7.15). A full sibling comparison, designed to adjust for shared familial factors, attenuated the estimates (aOR = 5.41; 95% CI, 4.65-6.30). When individuals with attention-deficit/hyperactivity disorder (ADHD) and pervasive developmental disorders were excluded, the association was also attenuated, whereas exclusion of other psychiatric comorbidities had minimal impact. Having persistent TS/CTD, comorbid ADHD, and taking ADHD medication greatly increased the likelihood of insomnia.CONCLUSIONS: Insomnia is significantly associated with TS/CTD, independently from somatic disorders, familial factors or psychiatric comorbidities, although familial factors, neurodevelopmental comorbidities, and ADHD/ADHD medication may explain part of the association. Insomnia should be routinely assessed and managed in TS/CTD, particularly in chronic patients and in those with comorbid ADHD. Other sleep disorders require further study. © 2021 The Authors. Movement Disorders published by Wiley Periodicals LLC on behalf of International Parkinson and Movement Disorder Society. | |
650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Psykiatri0 (SwePub)302152 hsv//swe |
650 | 7 | a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Psychiatry0 (SwePub)302152 hsv//eng |
653 | a Tourette syndrome | |
653 | a attention-deficit/hyperactivity disorder | |
653 | a chronic tic disorder | |
653 | a insomnia | |
653 | a sleep problems | |
700 | 1 | a Sidorchuk, Annau Karolinska Institutet4 aut |
700 | 1 | a Sevilla-Cermeño, Laurau Department of Child and Adolescent Psychiatry, Institute of Psychiatry and Mental Health, Hospital General Universitario Gregorio Marañón, School of Medicine, Universidad Complutense, IiSGM, CIBERSAM, Madrid, Spain4 aut |
700 | 1 | a Åkerstedt, Torbjörnu Karolinska Institutet4 aut |
700 | 1 | a Silverberg-Morse, Mariau Stockholm Health Care Services, Region Stockholm, Stockholm, Sweden4 aut |
700 | 1 | a Larsson, Henrik,d 1975-u Örebro universitet,Institutionen för medicinska vetenskaper,Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden4 aut0 (Swepub:oru)hiln |
700 | 1 | a Mataix-Cols, Davidu Karolinska Institutet4 aut |
700 | 1 | a Fernández de la Cruz, Lorenau Karolinska Institutet4 aut |
710 | 2 | a Karolinska Institutetb Department of Child and Adolescent Psychiatry, Institute of Psychiatry and Mental Health, Hospital General Universitario Gregorio Marañón, School of Medicine, Universidad Complutense, IiSGM, CIBERSAM, Madrid, Spain4 org |
773 | 0 | t Movement Disordersd : John Wiley & Sonsg 37:2, s. 392-400q 37:2<392-400x 0885-3185x 1531-8257 |
856 | 4 | u https://doi.org/10.1002/mds.28842y Fulltext |
856 | 4 | u https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/mds.28842 |
856 | 4 8 | u https://urn.kb.se/resolve?urn=urn:nbn:se:oru:diva-95179 |
856 | 4 8 | u https://doi.org/10.1002/mds.28842 |
856 | 4 8 | u http://kipublications.ki.se/Default.aspx?queryparsed=id:147930859 |
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