Sökning: L773:1475 0961 > (2015-2019) > Associations of lef...
Fältnamn | Indikatorer | Metadata |
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000 | 03709naa a2200409 4500 | |
001 | oai:DiVA.org:uu-372367 | |
003 | SwePub | |
008 | 190108s2019 | |||||||||||000 ||eng| | |
024 | 7 | a https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-3723672 URI |
024 | 7 | a https://doi.org/10.1111/cpf.125332 DOI |
040 | a (SwePub)uu | |
041 | a engb eng | |
042 | 9 SwePub | |
072 | 7 | a ref2 swepub-contenttype |
072 | 7 | a art2 swepub-publicationtype |
100 | 1 | a Henriksen, Egilu Vastmanland Cty Hosp, Dept Clin Physiol, SE-72189 Vasteras, Sweden4 aut |
245 | 1 0 | a Associations of left atrial volumes and Doppler filling indices with left atrial function in acute myocardial infarction |
264 | c 2018-07-01 | |
264 | 1 | b WILEY,c 2019 |
338 | a electronic2 rdacarrier | |
520 | a Recent findings suggest that left atrial (LA) function is more strongly related to adverse prognosis than LA volumes. We aimed to evaluate the associations between LA volumes and Doppler filling indices with LA function. Echocardiographic LA volumes (LAVs), mitral valve early (MV-E) and late (MV-A) peak flow velocities, and mitral atrioventricular plane tissue-Doppler early (TD-e ') and late (TD-a ') peak velocities were obtained in 320 patients with acute myocardial infarction (AMI) free from atrial fibrillation and more than moderate valvular disease. LA function was estimated as the LA emptying fraction (LAEF), that is 100x (LAVmax-LAVmin)/LAVmax. LA reservoir volume was calculated as LAVmax-LAVmin and LA transit volume as LV stroke volume-reservoir volume. In restricted cubic spline regression analyses with multivariable adjustment, a reduced LAEF was strongly associated with smaller reservoir volume, larger transit volume, LAVmax, LAVpreA and especially LAVmin. MV-E linearly increased with a lower LAEF, whereas MV-A decreased but only below LAEF levels of approximately 45%. The resulting E/A ratio showed a sudden increase in LAEF levels below similar to 45%. Lower TD-a ' was linearly associated with a lower LAEF. In conclusion, a reduced atrial function was associated with smaller LA reservoir volume, larger LA transit volume, lower TD-a ', a non-linear decrease in MV-A and a non-linear increase in E/A. Our findings are likely a reflection of the adaptation to sustain LV filling volume and counteracting a rise in pulmonary venous pressure in face of an enhanced LV end-diastolic pressure. | |
650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Kardiologi0 (SwePub)302062 hsv//swe |
650 | 7 | a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Cardiac and Cardiovascular Systems0 (SwePub)302062 hsv//eng |
653 | a diastolic function | |
653 | a Doppler indices | |
653 | a echocardiography | |
653 | a left atrium | |
653 | a myocardial infarction | |
700 | 1 | a Selmeryd, Jonasu Vastmanland Cty Hosp, Dept Clin Physiol, SE-72189 Vasteras, Sweden4 aut |
700 | 1 | a Hedberg, Päru Uppsala universitet,Centrum för klinisk forskning, Västerås,Vastmanland Cty Hosp, Dept Clin Physiol, SE-72189 Vasteras, Sweden4 aut0 (Swepub:uu)parhe939 |
710 | 2 | a Vastmanland Cty Hosp, Dept Clin Physiol, SE-72189 Vasteras, Swedenb Centrum för klinisk forskning, Västerås4 org |
773 | 0 | t Clinical Physiology and Functional Imagingd : WILEYg 39:1, s. 85-92q 39:1<85-92x 1475-0961x 1475-097X |
856 | 4 | u https://doi.org/10.1111/cpf.12533y Fulltext |
856 | 4 | u https://uu.diva-portal.org/smash/get/diva2:1276700/FULLTEXT01.pdfx primaryx Raw objecty fulltext:print |
856 | 4 | u https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/cpf.12533 |
856 | 4 8 | u https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-372367 |
856 | 4 8 | u https://doi.org/10.1111/cpf.12533 |
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