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Sökning: WFRF:(Ekberg Karin) > Late effects in pat...

LIBRIS Formathandbok  (Information om MARC21)
FältnamnIndikatorerMetadata
00005700naa a2200457 4500
001oai:DiVA.org:uu-500584
003SwePub
008230421s2023 | |||||||||||000 ||eng|
009oai:prod.swepub.kib.ki.se:152320669
009oai:lup.lub.lu.se:89e942d4-c623-4d6e-b305-cb4b502320dd
024a https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-5005842 URI
024a https://doi.org/10.1182/bloodadvances.20220072412 DOI
024a http://kipublications.ki.se/Default.aspx?queryparsed=id:1523206692 URI
024a https://lup.lub.lu.se/record/89e942d4-c623-4d6e-b305-cb4b502320dd2 URI
040 a (SwePub)uud (SwePub)kid (SwePub)lu
041 a engb eng
042 9 SwePub
072 7a ref2 swepub-contenttype
072 7a art2 swepub-publicationtype
100a Ekberg, Sarau Karolinska Institute,Karolinska Institutet,Uppsala universitet,Cancerprecisionsmedicin,Uppsala Akad Hosp, Uppsala, Sweden.;Karolinska Inst, Dept Med Solna, Clin Epidemiol Div, Stockholm, Sweden.,Uppsala University Hospital4 aut0 (Swepub:uu)sarek249
2451 0a Late effects in patients with mantle cell lymphoma treated with or without autologous stem cell transplantation
264 c 2023-03-14
264 1b Elsevier,c 2023
338 a electronic2 rdacarrier
520 a Studies on late effects in patients with mantle cell lymphoma (MCL) are becoming increasingly important as survival is improving, and novel targeted drugs are being introduced. However, knowledge about late effects is limited. The aim of this population-based study was to describe the magnitude and panorama of late effects among patients treated with or without high-dose chemotherapy with autologous stem cell transplantation (HD-ASCT). The study cohort included all patients with MCL, recorded in the Swedish Lymphoma Register, aged 18 to 69 years, diagnosed between 2000 and 2014 (N = 620; treated with HD-ASCT, n = 247) and 1:10 matched healthy comparators. Patients and comparators were followed up via the National Patient Register and Cause of Death Register, from 12 months after diagnosis or matching to December 2017. Incidence rate ratios of the numbers of outpatient visits, hospitalizations, and bed days were estimated using negative binomial regression models. In relation to the matched comparators, the rate of specialist and hospital visits was significantly higher among patients with MCL. Patients with MCL had especially high relative risks of infectious, respiratory, and blood disorders. Within this observation period, no difference in the rate of these complications, including secondary neoplasms, was observed between patients treated with and without HD-ASCT. Most of the patients died from their lymphoma and not from another cause or treatment complication. Taken together, our results imply that most of the posttreatment health care needs are related to the lymphoma disease itself, thus, indicating the need for more efficient treatment options.
650 7a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Hematologi0 (SwePub)302022 hsv//swe
650 7a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Hematology0 (SwePub)302022 hsv//eng
700a Smedby, Karin E.u Karolinska Institute,Karolinska Institutet,Karolinska University Hospital4 aut
700a Albertsson-Lindblad, Alexandrau Lund University,Lunds universitet,Medicinsk onkologi,Sektion I,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Lymfom - Klinisk forskning,Forskargrupper vid Lunds universitet,LUCC: Lunds universitets cancercentrum,Övriga starka forskningsmiljöer,Medical oncology,Section I,Department of Clinical Sciences, Lund,Faculty of Medicine,Lymphoma - Clinical Research,Lund University Research Groups,LUCC: Lund University Cancer Centre,Other Strong Research Environments,Skåne University Hospital4 aut0 (Swepub:lu)med-aab
700a Jerkeman, Matsu Lund University,Lunds universitet,Medicinsk onkologi,Sektion I,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Lymfom - Klinisk forskning,Forskargrupper vid Lunds universitet,LUCC: Lunds universitets cancercentrum,Övriga starka forskningsmiljöer,Onkologi övergripande,Institutionen för kliniska vetenskaper, Lund,Medical oncology,Section I,Department of Clinical Sciences, Lund,Faculty of Medicine,Lymphoma - Clinical Research,Lund University Research Groups,LUCC: Lund University Cancer Centre,Other Strong Research Environments,Oncology corporate,Department of Clinical Sciences, Lund,Skåne University Hospital4 aut0 (Swepub:lu)onk-mje
700a Weibull, Caroline E.u Karolinska Institute,Karolinska Institutet4 aut
700a Glimelius, Ingrid,d 1975-u Karolinska Institute,Karolinska Institutet,Uppsala universitet,Cancerprecisionsmedicin,Karolinska Inst, Dept Med Solna, Clin Epidemiol Div, Stockholm, Sweden.;Lund Univ, Skane Univ Hosp, Dept Clin Sci Lund, Div Oncol, Lund, Sweden.,Uppsala University Hospital4 aut0 (Swepub:uu)inggl846
710a Uppsala universitetb Cancerprecisionsmedicin4 org
773t Blood Advancesd : Elsevierg 7:5, s. 866-874q 7:5<866-874x 2473-9529x 2473-9537
856u https://doi.org/10.1182/bloodadvances.2022007241y Fulltext
856u https://uu.diva-portal.org/smash/get/diva2:1752409/FULLTEXT01.pdfx primaryx Raw objecty fulltext:print
856u http://dx.doi.org/10.1182/bloodadvances.2022007241x freey FULLTEXT
8564 8u https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-500584
8564 8u https://doi.org/10.1182/bloodadvances.2022007241
8564 8u http://kipublications.ki.se/Default.aspx?queryparsed=id:152320669
8564 8u https://lup.lub.lu.se/record/89e942d4-c623-4d6e-b305-cb4b502320dd

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