Genetic counselling in psoriasis: empirical data on psoriasis among first-degree relatives of 3095 psoriatic probands

• The risk of getting psoriasis dependent on the occurrence of psoriasis in the family has been determined empirically. Altogether 3717 families with one or both parents who had psoriasis have been analysed with regard to the number of children with or without psoriasis. The lifetime risk of getting psoriasis if no parent, one parent or both parents have psoriasis is 0.04, 0.28 and 0.65, respectively. If there is already one affected child in the family, the corresponding risks are 0.24, 0.51 and 0.83, respectively. The risk of getting psoriasis before the age of 32 years is dependent on the age-of-onset of psoriasis in one affected parent.

Subject headings

MEDICIN OCH HÄLSOVETENSKAP  -- Annan medicin och hälsovetenskap (hsv//swe)

MEDICAL AND HEALTH SCIENCES  -- Other Medical and Health Sciences (hsv//eng)

Keyword

Adolescent

Adult

Age Factors

Aged

Child

Child

Preschool

Family Characteristics

*Genetic Counseling

Human

Infant

Middle Aged

Pedigree

Psoriasis/*genetics

Risk Assessment

Support

Non-U.S. Gov't

Publication and Content Type

ref (subject category)

art (subject category)