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LIBRIS Formathandbok  (Information om MARC21)
FältnamnIndikatorerMetadata
00003392naa a2200565 4500
001oai:gup.ub.gu.se/315240
003SwePub
008240528s2022 | |||||||||||000 ||eng|
024a https://gup.ub.gu.se/publication/3152402 URI
024a https://doi.org/10.1080/20002297.2022.20474912 DOI
040 a (SwePub)gu
041 a eng
042 9 SwePub
072 7a ref2 swepub-contenttype
072 7a art2 swepub-publicationtype
100a Schwab, G.4 aut
2451 0a Lack of direct association between oral mucosal lesions and SARS-CoV-2 in a cohort of patients hospitalised with COVID-19
264 c 2022-03-10
264 1b Informa UK Limited,c 2022
520 a Background COVID-19 is a disease affecting various human organs and systems, in which the virus seeks to interact with angiotensin-converting enzyme 2 receptors. These receptors are present in the oral cavity, but the direct relationship between such an interaction and possible oral manifestations of COVID-19 is still unclear. Aim The present study evaluated oral manifestations in a cohort of COVID-19 patients during the period of hospitalisation. Methods In total, 154 patients presenting moderate-to-severe forms of COVID-19 had their oral mucosa examined twice a week until the final outcome, either discharge or death. The oral alterations observed in the patients were grouped into Group 1 (pre-existing conditions and opportunistic oral lesions) and Group 2 (oral mucosal changes related to hospitalization). Results Oral lesions found in the patients of Group 1 are not suggestive of SARS-CoV-2 infection as they are mainly caused by opportunistic infections. On the other hand, oral alterations found in the patients of Group 2 were statistically (P < 0.001) related to intubation and longer period of hospitalisation. Conclusion It is unlikely that ulcerative lesions in the oral cavity are a direct manifestation of SARS-CoV-2 or a marker of COVID-19 progression.
650 7a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Odontologi0 (SwePub)302162 hsv//swe
650 7a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Dentistry0 (SwePub)302162 hsv//eng
653 a Oral ulcer
653 a opportunistic infections
653 a COVID-19
653 a HSV-1
653 a SARS-CoV-2
653 a simplex-virus infection
653 a ace2
653 a Microbiology
700a Palmieri, M.4 aut
700a Zerbinati, R. M.4 aut
700a Sarmento, D. J. S.4 aut
700a Reis, T.4 aut
700a Ortega, K. L.4 aut
700a Kano, I. T.4 aut
700a Caixeta, R. A. V.4 aut
700a Hasséus, Bengt,d 1955u Gothenburg University,Göteborgs universitet,Institutionen för odontologi, sektion 1,Institute of Odontology, Section 14 aut0 (Swepub:gu)xhasbe
700a Sapkota, D.4 aut
700a Junges, R.4 aut
700a Giannecchini, S.4 aut
700a Costa, A. L. F.4 aut
700a Jales, Smcp4 aut
700a Lindoso, J. A. L.4 aut
700a Gallo, C. B.4 aut
700a Braz-Silva, P. H.4 aut
710a Göteborgs universitetb Institutionen för odontologi, sektion 14 org
773t Journal of Oral Microbiologyd : Informa UK Limitedg 14:1q 14:1x 2000-2297
8564 8u https://gup.ub.gu.se/publication/315240
8564 8u https://doi.org/10.1080/20002297.2022.2047491

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